Differential health effects on inflammatory, immunological and stress parameters in professional soccer players and sedentary individuals after consuming a synbiotic. A triple blinded, randomized, placebo-controlled pilot study.

Daniela Quero, Carmen; Manonelles, Pedro; Fernández, Marta; Abellán Aynés, Oriol; López Plaza, Daniel; Andreu Caravaca, Luis; Hinchado, María Dolores; Gálvez, Isabel; Ortega, Eduardo

Differential health effects on inflammatory, immunological and stress parameters in professional soccer players and sedentary individuals after consuming a synbiotic. A triple blinded, randomized, placebo-controlled pilot study.

The main objective of this research was to carry out an experimental study, triple-blind, on the possible immunophysiological effects of a nutritional supplement (synbiotic, Gasteel Plus®, Heel España S.A.U.), containing a mixture of probiotic strains, such as Bifidobacterium lactis CBP-001010, Lact...

Descripción completa

Detalles Bibliográficos
Autores:	Daniela Quero, Carmen, Manonelles, Pedro, Fernández, Marta, Abellán Aynés, Oriol, López Plaza, Daniel, Andreu Caravaca, Luis, Hinchado, María Dolores, Gálvez, Isabel, Ortega, Eduardo
Tipo de recurso:	artículo
Fecha de publicación:	2021
País:	España
Institución:	Universidad Católica San Antonio de Murcia (UCAM)
Repositorio:	RIUCAM. Repositorio Institucional de la Universidad Católica San Antonio de Murcia
OAI Identifier:	oai:repositorio.ucam.edu:10952/7162
Acceso en línea:	http://hdl.handle.net/10952/7162
Access Level:	acceso abierto
Palabra clave:	Anxiety Immunity Inflammation Prebiotic Probiotics Sedentarism Soccer Stress Synbiotic

id	ES_dd923780177e89767014bdab4ffd23d2
oai_identifier_str	oai:repositorio.ucam.edu:10952/7162
network_acronym_str	ES
network_name_str	España
repository_id_str
spelling	Differential health effects on inflammatory, immunological and stress parameters in professional soccer players and sedentary individuals after consuming a synbiotic. A triple blinded, randomized, placebo-controlled pilot study.Daniela Quero, CarmenManonelles, PedroFernández, MartaAbellán Aynés, OriolLópez Plaza, DanielAndreu Caravaca, LuisHinchado, María DoloresGálvez, IsabelOrtega, EduardoAnxietyImmunityInflammationPrebioticProbioticsSedentarismSoccerStressSynbioticThe main objective of this research was to carry out an experimental study, triple-blind, on the possible immunophysiological effects of a nutritional supplement (synbiotic, Gasteel Plus®, Heel España S.A.U.), containing a mixture of probiotic strains, such as Bifidobacterium lactis CBP-001010, Lactobacillus rhamnosus CNCM I-4036, and Bifidobacterium longum ES1, as well as the prebiotic fructooligosaccharides, on both professional athletes and sedentary people. The effects on some inflammatory/immune (IL-1β, IL-10, and immunoglobulin A) and stress (epinephrine, norepinephrine, dopamine, serotonin, corticotropin-releasing hormone (CRH), Adrenocorticotropic hormone (ACTH), and cortisol) biomarkers were evaluated, determined by flow cytometer and ELISA. The effects on metabolic profile and physical activity, as well as on various parameters that could affect physical and mental health, were also evaluated via the use of accelerometry and validated questionnaires. The participants were professional soccer players in the Second Division B of the Spanish League and sedentary students of the same sex and age range. Both study groups were randomly divided into two groups: a control group-administered with placebo, and an experimental group-administered with the synbiotic. Each participant was evaluated at baseline, as well as after the intervention, which lasted one month. Only in the athlete group did the synbiotic intervention clearly improve objective physical activity and sleep quality, as well as perceived general health, stress, and anxiety levels. Furthermore, the synbiotic induced an immunophysiological bioregulatory effect, depending on the basal situation of each experimental group, particularly in the systemic levels of IL-1β (increased significantly only in the sedentary group), CRH (decreased significantly only in the sedentary group), and dopamine (increased significantly only in the athlete group). There were no significant differences between groups in the levels of immunoglobulin A or in the metabolic profile as a result of the intervention. It is concluded that synbiotic nutritional supplements can improve anxiety, stress, and sleep quality, particularly in sportspeople, which appears to be linked to an improved immuno-neuroendocrine response in which IL-1β, CRH, and dopamine are clearly involved.Actividad Física y Deporte2021info:eu-repo/semantics/articlehttp://hdl.handle.net/10952/7162reponame:RIUCAM. Repositorio Institucional de la Universidad Católica San Antonio de Murciainstname:Universidad Católica San Antonio de Murcia (UCAM)Inglésinfo:eu-repo/semantics/openAccessoai:repositorio.ucam.edu:10952/71622026-06-07T18:35:21Z
dc.title.none.fl_str_mv	Differential health effects on inflammatory, immunological and stress parameters in professional soccer players and sedentary individuals after consuming a synbiotic. A triple blinded, randomized, placebo-controlled pilot study.
title	Differential health effects on inflammatory, immunological and stress parameters in professional soccer players and sedentary individuals after consuming a synbiotic. A triple blinded, randomized, placebo-controlled pilot study.
spellingShingle	Differential health effects on inflammatory, immunological and stress parameters in professional soccer players and sedentary individuals after consuming a synbiotic. A triple blinded, randomized, placebo-controlled pilot study. Daniela Quero, Carmen Anxiety Immunity Inflammation Prebiotic Probiotics Sedentarism Soccer Stress Synbiotic
title_short	Differential health effects on inflammatory, immunological and stress parameters in professional soccer players and sedentary individuals after consuming a synbiotic. A triple blinded, randomized, placebo-controlled pilot study.
title_full	Differential health effects on inflammatory, immunological and stress parameters in professional soccer players and sedentary individuals after consuming a synbiotic. A triple blinded, randomized, placebo-controlled pilot study.
title_fullStr	Differential health effects on inflammatory, immunological and stress parameters in professional soccer players and sedentary individuals after consuming a synbiotic. A triple blinded, randomized, placebo-controlled pilot study.
title_full_unstemmed	Differential health effects on inflammatory, immunological and stress parameters in professional soccer players and sedentary individuals after consuming a synbiotic. A triple blinded, randomized, placebo-controlled pilot study.
title_sort	Differential health effects on inflammatory, immunological and stress parameters in professional soccer players and sedentary individuals after consuming a synbiotic. A triple blinded, randomized, placebo-controlled pilot study.
dc.creator.none.fl_str_mv	Daniela Quero, Carmen Manonelles, Pedro Fernández, Marta Abellán Aynés, Oriol López Plaza, Daniel Andreu Caravaca, Luis Hinchado, María Dolores Gálvez, Isabel Ortega, Eduardo
author	Daniela Quero, Carmen
author_facet	Daniela Quero, Carmen Manonelles, Pedro Fernández, Marta Abellán Aynés, Oriol López Plaza, Daniel Andreu Caravaca, Luis Hinchado, María Dolores Gálvez, Isabel Ortega, Eduardo
author_role	author
author2	Manonelles, Pedro Fernández, Marta Abellán Aynés, Oriol López Plaza, Daniel Andreu Caravaca, Luis Hinchado, María Dolores Gálvez, Isabel Ortega, Eduardo
author2_role	author author author author author author author author
dc.subject.none.fl_str_mv	Anxiety Immunity Inflammation Prebiotic Probiotics Sedentarism Soccer Stress Synbiotic
topic	Anxiety Immunity Inflammation Prebiotic Probiotics Sedentarism Soccer Stress Synbiotic
description	The main objective of this research was to carry out an experimental study, triple-blind, on the possible immunophysiological effects of a nutritional supplement (synbiotic, Gasteel Plus®, Heel España S.A.U.), containing a mixture of probiotic strains, such as Bifidobacterium lactis CBP-001010, Lactobacillus rhamnosus CNCM I-4036, and Bifidobacterium longum ES1, as well as the prebiotic fructooligosaccharides, on both professional athletes and sedentary people. The effects on some inflammatory/immune (IL-1β, IL-10, and immunoglobulin A) and stress (epinephrine, norepinephrine, dopamine, serotonin, corticotropin-releasing hormone (CRH), Adrenocorticotropic hormone (ACTH), and cortisol) biomarkers were evaluated, determined by flow cytometer and ELISA. The effects on metabolic profile and physical activity, as well as on various parameters that could affect physical and mental health, were also evaluated via the use of accelerometry and validated questionnaires. The participants were professional soccer players in the Second Division B of the Spanish League and sedentary students of the same sex and age range. Both study groups were randomly divided into two groups: a control group-administered with placebo, and an experimental group-administered with the synbiotic. Each participant was evaluated at baseline, as well as after the intervention, which lasted one month. Only in the athlete group did the synbiotic intervention clearly improve objective physical activity and sleep quality, as well as perceived general health, stress, and anxiety levels. Furthermore, the synbiotic induced an immunophysiological bioregulatory effect, depending on the basal situation of each experimental group, particularly in the systemic levels of IL-1β (increased significantly only in the sedentary group), CRH (decreased significantly only in the sedentary group), and dopamine (increased significantly only in the athlete group). There were no significant differences between groups in the levels of immunoglobulin A or in the metabolic profile as a result of the intervention. It is concluded that synbiotic nutritional supplements can improve anxiety, stress, and sleep quality, particularly in sportspeople, which appears to be linked to an improved immuno-neuroendocrine response in which IL-1β, CRH, and dopamine are clearly involved.
publishDate	2021
dc.date.none.fl_str_mv	2021
dc.type.none.fl_str_mv	info:eu-repo/semantics/article
format	article
dc.identifier.none.fl_str_mv	http://hdl.handle.net/10952/7162
url	http://hdl.handle.net/10952/7162
dc.language.none.fl_str_mv	Inglés
language_invalid_str_mv	Inglés
dc.rights.none.fl_str_mv	info:eu-repo/semantics/openAccess
eu_rights_str_mv	openAccess
dc.source.none.fl_str_mv	reponame:RIUCAM. Repositorio Institucional de la Universidad Católica San Antonio de Murcia instname:Universidad Católica San Antonio de Murcia (UCAM)
instname_str	Universidad Católica San Antonio de Murcia (UCAM)
reponame_str	RIUCAM. Repositorio Institucional de la Universidad Católica San Antonio de Murcia
collection	RIUCAM. Repositorio Institucional de la Universidad Católica San Antonio de Murcia
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_	1869421872089661440
score	15,298079

Differential health effects on inflammatory, immunological and stress parameters in professional soccer players and sedentary individuals after consuming a synbiotic. A triple blinded, randomized, placebo-controlled pilot study.

Similares en LA Referencia