Explicit criteria for Potentially Inappropriate Medications in Older Adults: A comprehensive systematic review.

Context: Potentially inappropriate medications (PIMs) refer to the use of a medication whose risks outweigh the potential benefits in older adults, especially when other effective alternatives are available.</p><p>Aims: To identify and analyze explicit criteria developed for detecting PI...

Descripción completa

Detalles Bibliográficos
Autores: Alemán Fernández, Eliezer, Siverio Mota, Dany, Vicet Muro, Liliana, Braza Reyes, Antonio J., Viñas Bastart, Montserrat, Modamio Charles, Pilar, Delgado-Hernández, René
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2025
País:España
Institución:Universidad de Barcelona
Repositorio:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/224776
Acceso en línea:https://hdl.handle.net/2445/224776
Access Level:acceso abierto
Palabra clave:Persones grans
Medicaments
Envelliment
Older people
Drugs
Aging
id ES_dcaa8bf3f711bb652ed560ac9138efc0
oai_identifier_str oai:diposit.ub.edu:2445/224776
network_acronym_str ES
network_name_str España
repository_id_str
spelling Explicit criteria for Potentially Inappropriate Medications in Older Adults: A comprehensive systematic review.Alemán Fernández, EliezerSiverio Mota, DanyVicet Muro, LilianaBraza Reyes, Antonio J.Viñas Bastart, MontserratModamio Charles, PilarDelgado-Hernández, RenéPersones gransMedicamentsEnvellimentOlder peopleDrugsAgingContext: Potentially inappropriate medications (PIMs) refer to the use of a medication whose risks outweigh the potential benefits in older adults, especially when other effective alternatives are available.</p><p>Aims: To identify and analyze explicit criteria developed for detecting PIMs in older adults, highlighting methodological approaches and pharmacological classifications.</p><p>Methods: A comprehensive literature search was conducted across seven databases from January 1990 to December 2024, following the PRISMA 2020 guidelines. Criteria developed using expert consensus or evidence-based processes were included.</p><p>Results: Out of 3,119 articles, 68 met the inclusion criteria. The Beers and STOPP/START tools were most frequently cited. The Delphi method was the predominant approach for validating the selected tools (73.53%). Commonly flagged medications included tricyclic antidepressants, NSAIDs, and benzodiazepines.</p><p>Conclusions: Numerous validated tools exist, although variations in validation methods and drug classification were observed. A global update and harmonization of explicit criteria are necessary for improved geriatric pharmacotherapy.</p><p>Keywords: Beers criteria; Delphi method; deprescribing tools; older adults; potentially inappropriate medications; STOPP START criteria.GarVal Editorial2025info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://hdl.handle.net/2445/224776Articles publicats en revistes (Farmàcia, Tecnologia Farmacèutica i Fisicoquímica)reponame:Dipòsit Digital de la UBinstname:Universidad de BarcelonaInglésReproducció del document publicat a: https://doi.org/10.56499/jppres25.2487_13.6.1797Journal of Pharmacy & Pharmacognosy Research, 2025, vol. 13, num.6, p. 1797-1818https://doi.org/10.56499/jppres25.2487_13.6.1797cc-by-nc (c) Alemán-Fernández E et al., 2025http://creativecommons.org/licenses/by-nc/4.0/info:eu-repo/semantics/openAccessoai:diposit.ub.edu:2445/2247762026-05-27T06:46:51Z
dc.title.none.fl_str_mv Explicit criteria for Potentially Inappropriate Medications in Older Adults: A comprehensive systematic review.
title Explicit criteria for Potentially Inappropriate Medications in Older Adults: A comprehensive systematic review.
spellingShingle Explicit criteria for Potentially Inappropriate Medications in Older Adults: A comprehensive systematic review.
Alemán Fernández, Eliezer
Persones grans
Medicaments
Envelliment
Older people
Drugs
Aging
title_short Explicit criteria for Potentially Inappropriate Medications in Older Adults: A comprehensive systematic review.
title_full Explicit criteria for Potentially Inappropriate Medications in Older Adults: A comprehensive systematic review.
title_fullStr Explicit criteria for Potentially Inappropriate Medications in Older Adults: A comprehensive systematic review.
title_full_unstemmed Explicit criteria for Potentially Inappropriate Medications in Older Adults: A comprehensive systematic review.
title_sort Explicit criteria for Potentially Inappropriate Medications in Older Adults: A comprehensive systematic review.
dc.creator.none.fl_str_mv Alemán Fernández, Eliezer
Siverio Mota, Dany
Vicet Muro, Liliana
Braza Reyes, Antonio J.
Viñas Bastart, Montserrat
Modamio Charles, Pilar
Delgado-Hernández, René
author Alemán Fernández, Eliezer
author_facet Alemán Fernández, Eliezer
Siverio Mota, Dany
Vicet Muro, Liliana
Braza Reyes, Antonio J.
Viñas Bastart, Montserrat
Modamio Charles, Pilar
Delgado-Hernández, René
author_role author
author2 Siverio Mota, Dany
Vicet Muro, Liliana
Braza Reyes, Antonio J.
Viñas Bastart, Montserrat
Modamio Charles, Pilar
Delgado-Hernández, René
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv Persones grans
Medicaments
Envelliment
Older people
Drugs
Aging
topic Persones grans
Medicaments
Envelliment
Older people
Drugs
Aging
description Context: Potentially inappropriate medications (PIMs) refer to the use of a medication whose risks outweigh the potential benefits in older adults, especially when other effective alternatives are available.</p><p>Aims: To identify and analyze explicit criteria developed for detecting PIMs in older adults, highlighting methodological approaches and pharmacological classifications.</p><p>Methods: A comprehensive literature search was conducted across seven databases from January 1990 to December 2024, following the PRISMA 2020 guidelines. Criteria developed using expert consensus or evidence-based processes were included.</p><p>Results: Out of 3,119 articles, 68 met the inclusion criteria. The Beers and STOPP/START tools were most frequently cited. The Delphi method was the predominant approach for validating the selected tools (73.53%). Commonly flagged medications included tricyclic antidepressants, NSAIDs, and benzodiazepines.</p><p>Conclusions: Numerous validated tools exist, although variations in validation methods and drug classification were observed. A global update and harmonization of explicit criteria are necessary for improved geriatric pharmacotherapy.</p><p>Keywords: Beers criteria; Delphi method; deprescribing tools; older adults; potentially inappropriate medications; STOPP START criteria.
publishDate 2025
dc.date.none.fl_str_mv 2025
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/224776
url https://hdl.handle.net/2445/224776
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Reproducció del document publicat a: https://doi.org/10.56499/jppres25.2487_13.6.1797
Journal of Pharmacy & Pharmacognosy Research, 2025, vol. 13, num.6, p. 1797-1818
https://doi.org/10.56499/jppres25.2487_13.6.1797
dc.rights.none.fl_str_mv cc-by-nc (c) Alemán-Fernández E et al., 2025
http://creativecommons.org/licenses/by-nc/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv cc-by-nc (c) Alemán-Fernández E et al., 2025
http://creativecommons.org/licenses/by-nc/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv GarVal Editorial
publisher.none.fl_str_mv GarVal Editorial
dc.source.none.fl_str_mv Articles publicats en revistes (Farmàcia, Tecnologia Farmacèutica i Fisicoquímica)
reponame:Dipòsit Digital de la UB
instname:Universidad de Barcelona
instname_str Universidad de Barcelona
reponame_str Dipòsit Digital de la UB
collection Dipòsit Digital de la UB
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869421789521641472
score 15.812429

Similares en LA Referencia