Detecting Postural Instability in Parkinson's Disease From IMU-Based Objective Measures
Parkinson’s Disease (PD) is a progressive neurological disorder that affects both motor and non-motor functions. A critical aspect of PD is postural instability, which is associated with a higher risk of falls and a significant decline in mobility. The onset of postural instability is frequently ide...
| Autores: | , , , , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2025 |
| País: | España |
| Institución: | Consejo Superior de Investigaciones Científicas (CSIC) |
| Repositorio: | DIGITAL.CSIC. Repositorio Institucional del CSIC |
| OAI Identifier: | oai:digital.csic.es:10261/417733 |
| Acceso en línea: | http://hdl.handle.net/10261/417733 |
| Access Level: | acceso abierto |
| Palabra clave: | Accelerometer H&Y Hoehn and Yahr IMU inertial measurement unit Parkinson’s disease postural instability postural reactions pull test |
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Detecting Postural Instability in Parkinson's Disease From IMU-Based Objective MeasuresSmith, KendalTorricelli, DiegoGonzalez Sanchez, MiguelPérez-Sánchez, Javier RicardoLuque Buzo, ElisaGrandas, FranciscoMarin, Juan MiguelGomez Garcia, Jorge AndrésAccelerometerH&YHoehn and YahrIMUinertial measurement unitParkinson’s diseasepostural instabilitypostural reactionspull testParkinson’s Disease (PD) is a progressive neurological disorder that affects both motor and non-motor functions. A critical aspect of PD is postural instability, which is associated with a higher risk of falls and a significant decline in mobility. The onset of postural instability is frequently identified through subjective clinical assessments such as the pull test, which aligns with the transition from Stage II to Stage III on the Hoehn and Yahr (H&Y) scale, a measure of general motor impairment. This study aims to pinpoint this transition by providing an objective quantification of the pull test, to prevent falls and manage severe motor symptoms via early detection. Sixty objective metrics were characterised from acceleration data using inertial measurement units (IMU) during pull tests conducted with 30 PD patients to differentiate between H&Y Stages II and III. Significant differences in feature distributions were identified, with two features achieving a ROC AUC of 0.95: chest to lumbar maximum acceleration ratio, and power ratio of 8-12 Hz versus total acceleration power. This paper demonstrates the ability of certain IMU-derived features to distinguish between H&Y Stages II and III, presenting more straightforward and objective measurements compared to conventional pull test metrics. Furthermore, the study explores the inconsistencies in the administration of the pull test by different examiners and shows that even with these inconsistencies, objective measures can still effectively differentiate between stages. To the best of our knowledge, this work represents the first extensive attempt to objectively quantify the pull test for this type of classification.This work was supported in part by the AI4HealthyAging through Spanish Ministry of Economy and Digital transformation under Grant MIA.2021.M02.0007, in part by European Union NextGenerationEU/Plan de Recuperación, Transformación y Resiliencia (PRTR), and in part by the Ministerio de Ciencia, Innovación y Universidades (MCIN)/Agencia Estatal de Investigaciones (AEI)/10.13039/501100011033 through NEUROMARK Project under Grant PID2020-120491RA-I00.Peer reviewedInstitute of Electrical and Electronics EngineersMinisterio de Economía y Competitividad (España)Ministerio de Ciencia e Innovación (España)Agencia Estatal de Investigación (España)Smith, Kendal [0009-0006-2178-6235]Torricelli, Diego [0000-0001-8767-3395]Gonzalez Sanchez, Miguel [0000-0001-5076-5077]Perez Sanchez, Javier Ricardo [0000-0001-9292-9471]Luque Buzo, Elisa [0000-0002-7983-9268]Grandas, Francisco [0000-0001-6547-7617]Marin, Juan Miguel [0000-0002-6744-6475]Gomez Garcia, Jorge Andrés [0000-0002-6060-387X]Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]202620262025info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Publisher's versioninfo:eu-repo/semantics/publishedVersionhttp://hdl.handle.net/10261/417733reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Inglés#PLACEHOLDER_PARENT_METADATA_VALUE#https://doi.org/10.1109/tnsre.2025.3573455Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/4177332026-05-22T06:33:51Z |
| dc.title.none.fl_str_mv |
Detecting Postural Instability in Parkinson's Disease From IMU-Based Objective Measures |
| title |
Detecting Postural Instability in Parkinson's Disease From IMU-Based Objective Measures |
| spellingShingle |
Detecting Postural Instability in Parkinson's Disease From IMU-Based Objective Measures Smith, Kendal Accelerometer H&Y Hoehn and Yahr IMU inertial measurement unit Parkinson’s disease postural instability postural reactions pull test |
| title_short |
Detecting Postural Instability in Parkinson's Disease From IMU-Based Objective Measures |
| title_full |
Detecting Postural Instability in Parkinson's Disease From IMU-Based Objective Measures |
| title_fullStr |
Detecting Postural Instability in Parkinson's Disease From IMU-Based Objective Measures |
| title_full_unstemmed |
Detecting Postural Instability in Parkinson's Disease From IMU-Based Objective Measures |
| title_sort |
Detecting Postural Instability in Parkinson's Disease From IMU-Based Objective Measures |
| dc.creator.none.fl_str_mv |
Smith, Kendal Torricelli, Diego Gonzalez Sanchez, Miguel Pérez-Sánchez, Javier Ricardo Luque Buzo, Elisa Grandas, Francisco Marin, Juan Miguel Gomez Garcia, Jorge Andrés |
| author |
Smith, Kendal |
| author_facet |
Smith, Kendal Torricelli, Diego Gonzalez Sanchez, Miguel Pérez-Sánchez, Javier Ricardo Luque Buzo, Elisa Grandas, Francisco Marin, Juan Miguel Gomez Garcia, Jorge Andrés |
| author_role |
author |
| author2 |
Torricelli, Diego Gonzalez Sanchez, Miguel Pérez-Sánchez, Javier Ricardo Luque Buzo, Elisa Grandas, Francisco Marin, Juan Miguel Gomez Garcia, Jorge Andrés |
| author2_role |
author author author author author author author |
| dc.contributor.none.fl_str_mv |
Ministerio de Economía y Competitividad (España) Ministerio de Ciencia e Innovación (España) Agencia Estatal de Investigación (España) Smith, Kendal [0009-0006-2178-6235] Torricelli, Diego [0000-0001-8767-3395] Gonzalez Sanchez, Miguel [0000-0001-5076-5077] Perez Sanchez, Javier Ricardo [0000-0001-9292-9471] Luque Buzo, Elisa [0000-0002-7983-9268] Grandas, Francisco [0000-0001-6547-7617] Marin, Juan Miguel [0000-0002-6744-6475] Gomez Garcia, Jorge Andrés [0000-0002-6060-387X] Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72] |
| dc.subject.none.fl_str_mv |
Accelerometer H&Y Hoehn and Yahr IMU inertial measurement unit Parkinson’s disease postural instability postural reactions pull test |
| topic |
Accelerometer H&Y Hoehn and Yahr IMU inertial measurement unit Parkinson’s disease postural instability postural reactions pull test |
| description |
Parkinson’s Disease (PD) is a progressive neurological disorder that affects both motor and non-motor functions. A critical aspect of PD is postural instability, which is associated with a higher risk of falls and a significant decline in mobility. The onset of postural instability is frequently identified through subjective clinical assessments such as the pull test, which aligns with the transition from Stage II to Stage III on the Hoehn and Yahr (H&Y) scale, a measure of general motor impairment. This study aims to pinpoint this transition by providing an objective quantification of the pull test, to prevent falls and manage severe motor symptoms via early detection. Sixty objective metrics were characterised from acceleration data using inertial measurement units (IMU) during pull tests conducted with 30 PD patients to differentiate between H&Y Stages II and III. Significant differences in feature distributions were identified, with two features achieving a ROC AUC of 0.95: chest to lumbar maximum acceleration ratio, and power ratio of 8-12 Hz versus total acceleration power. This paper demonstrates the ability of certain IMU-derived features to distinguish between H&Y Stages II and III, presenting more straightforward and objective measurements compared to conventional pull test metrics. Furthermore, the study explores the inconsistencies in the administration of the pull test by different examiners and shows that even with these inconsistencies, objective measures can still effectively differentiate between stages. To the best of our knowledge, this work represents the first extensive attempt to objectively quantify the pull test for this type of classification. |
| publishDate |
2025 |
| dc.date.none.fl_str_mv |
2025 2026 2026 |
| dc.type.none.fl_str_mv |
info:eu-repo/semantics/article http://purl.org/coar/resource_type/c_6501 Publisher's version info:eu-repo/semantics/publishedVersion |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.none.fl_str_mv |
http://hdl.handle.net/10261/417733 |
| url |
http://hdl.handle.net/10261/417733 |
| dc.language.none.fl_str_mv |
Inglés |
| language_invalid_str_mv |
Inglés |
| dc.relation.none.fl_str_mv |
#PLACEHOLDER_PARENT_METADATA_VALUE# https://doi.org/10.1109/tnsre.2025.3573455 Sí |
| dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess |
| eu_rights_str_mv |
openAccess |
| dc.publisher.none.fl_str_mv |
Institute of Electrical and Electronics Engineers |
| publisher.none.fl_str_mv |
Institute of Electrical and Electronics Engineers |
| dc.source.none.fl_str_mv |
reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC instname:Consejo Superior de Investigaciones Científicas (CSIC) |
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Consejo Superior de Investigaciones Científicas (CSIC) |
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DIGITAL.CSIC. Repositorio Institucional del CSIC |
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DIGITAL.CSIC. Repositorio Institucional del CSIC |
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