Medication patterns in older adults with multimorbidity
Background: Older adults suffer from various chronic conditions which make them particularly vulnerable. The proper management of multiple drug use is therefore crucial. The aim of our study was to describe drug prescription and medication patterns in this population. Methods: A cross-sectional stud...
| Autores: | , , , , , , |
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| Formato: | artículo |
| Fecha de publicación: | 2019 |
| País: | España |
| Recursos: | Universitat Autònoma de Barcelona |
| Repositorio: | Dipòsit Digital de Documents de la UAB |
| Idioma: | inglés |
| OAI Identifier: | oai:ddd.uab.cat:223146 |
| Acesso em linha: | https://ddd.uab.cat/record/223146 https://dx.doi.org/urn:doi:10.1186/s12875-019-0969-9 |
| Access Level: | acceso abierto |
| Palavra-chave: | Ageing Cluster analysis Drugs Electronic health records Multimorbidity Primary health care |
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Medication patterns in older adults with multimorbiditya cluster analysis of primary care patientsGuisado-Clavero, Marina|||0000-0002-8448-2929Violán, Concepció|||0000-0003-3309-5360López-Jimenez, TomásRoso-Llorach, Albert|||0000-0002-9264-0405Pons-Vigués, Mariona|||0000-0002-7929-3701Muñoz, Miguel-Angel|||0000-0002-4083-3248Foguet-Boreu, Quintí|||0000-0002-6069-5305AgeingCluster analysisDrugsElectronic health recordsMultimorbidityPrimary health careBackground: Older adults suffer from various chronic conditions which make them particularly vulnerable. The proper management of multiple drug use is therefore crucial. The aim of our study was to describe drug prescription and medication patterns in this population. Methods: A cross-sectional study in Barcelona (Spain) using electronic health records from 50 primary healthcare centres. Participants were aged 65 to 94 years, presenting multimorbidity (≥2 chronic diseases), and had been prescribed at least 1 drug for 6 months or longer during 2009. We calculated the prevalence of prescribed drugs and identified medication patterns using multiple correspondence analysis and k-means clustering. Analyses were stratified by sex and age (65-79, 80-94 years). Results: We studied 164,513 patients (66.8% women) prescribed a median of 4 drugs (interquartile range [IQR] = 3-7) in the 65-79 age-group and 6 drugs (IQR = 4-8) in the 80-94 age-group. A minimum of 45.9% of patients aged 65-79 years, and 61.8% of those aged 80-94 years, were prescribed 5 or more drugs. We identified 6 medication patterns, a non-specific one and 5 encompassing 8 anatomical groups (alimentary tract and metabolism, blood, cardiovascular, dermatological, musculo-skeletal, neurological, respiratory, and sensory organ). Conclusions: Drug prescription is widespread among the elderly. Six medication patterns were identified, 5 of which were related to one or more anatomical group, with associations among drugs from different systems. Overall, guidelines do not accurately reflect the situation of the elderly multimorbid, new strategies for managing multiple drug uses are needed to optimize prescribing in these patients.Universitat Autònoma de Barcelona 22019-01-0120192019-01-01Articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://ddd.uab.cat/record/223146https://dx.doi.org/urn:doi:10.1186/s12875-019-0969-9reponame:Dipòsit Digital de Documents de la UABinstname:Universitat Autònoma de BarcelonaInglésengopen accesshttp://purl.org/coar/access_right/c_abf2Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.https://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:ddd.uab.cat:2231462026-06-06T12:50:31Z |
| dc.title.none.fl_str_mv |
Medication patterns in older adults with multimorbidity a cluster analysis of primary care patients |
| title |
Medication patterns in older adults with multimorbidity |
| spellingShingle |
Medication patterns in older adults with multimorbidity Guisado-Clavero, Marina|||0000-0002-8448-2929 Ageing Cluster analysis Drugs Electronic health records Multimorbidity Primary health care |
| title_short |
Medication patterns in older adults with multimorbidity |
| title_full |
Medication patterns in older adults with multimorbidity |
| title_fullStr |
Medication patterns in older adults with multimorbidity |
| title_full_unstemmed |
Medication patterns in older adults with multimorbidity |
| title_sort |
Medication patterns in older adults with multimorbidity |
| dc.creator.none.fl_str_mv |
Guisado-Clavero, Marina|||0000-0002-8448-2929 Violán, Concepció|||0000-0003-3309-5360 López-Jimenez, Tomás Roso-Llorach, Albert|||0000-0002-9264-0405 Pons-Vigués, Mariona|||0000-0002-7929-3701 Muñoz, Miguel-Angel|||0000-0002-4083-3248 Foguet-Boreu, Quintí|||0000-0002-6069-5305 |
| author |
Guisado-Clavero, Marina|||0000-0002-8448-2929 |
| author_facet |
Guisado-Clavero, Marina|||0000-0002-8448-2929 Violán, Concepció|||0000-0003-3309-5360 López-Jimenez, Tomás Roso-Llorach, Albert|||0000-0002-9264-0405 Pons-Vigués, Mariona|||0000-0002-7929-3701 Muñoz, Miguel-Angel|||0000-0002-4083-3248 Foguet-Boreu, Quintí|||0000-0002-6069-5305 |
| author_role |
author |
| author2 |
Violán, Concepció|||0000-0003-3309-5360 López-Jimenez, Tomás Roso-Llorach, Albert|||0000-0002-9264-0405 Pons-Vigués, Mariona|||0000-0002-7929-3701 Muñoz, Miguel-Angel|||0000-0002-4083-3248 Foguet-Boreu, Quintí|||0000-0002-6069-5305 |
| author2_role |
author author author author author author |
| dc.contributor.none.fl_str_mv |
Universitat Autònoma de Barcelona |
| dc.subject.none.fl_str_mv |
Ageing Cluster analysis Drugs Electronic health records Multimorbidity Primary health care |
| topic |
Ageing Cluster analysis Drugs Electronic health records Multimorbidity Primary health care |
| description |
Background: Older adults suffer from various chronic conditions which make them particularly vulnerable. The proper management of multiple drug use is therefore crucial. The aim of our study was to describe drug prescription and medication patterns in this population. Methods: A cross-sectional study in Barcelona (Spain) using electronic health records from 50 primary healthcare centres. Participants were aged 65 to 94 years, presenting multimorbidity (≥2 chronic diseases), and had been prescribed at least 1 drug for 6 months or longer during 2009. We calculated the prevalence of prescribed drugs and identified medication patterns using multiple correspondence analysis and k-means clustering. Analyses were stratified by sex and age (65-79, 80-94 years). Results: We studied 164,513 patients (66.8% women) prescribed a median of 4 drugs (interquartile range [IQR] = 3-7) in the 65-79 age-group and 6 drugs (IQR = 4-8) in the 80-94 age-group. A minimum of 45.9% of patients aged 65-79 years, and 61.8% of those aged 80-94 years, were prescribed 5 or more drugs. We identified 6 medication patterns, a non-specific one and 5 encompassing 8 anatomical groups (alimentary tract and metabolism, blood, cardiovascular, dermatological, musculo-skeletal, neurological, respiratory, and sensory organ). Conclusions: Drug prescription is widespread among the elderly. Six medication patterns were identified, 5 of which were related to one or more anatomical group, with associations among drugs from different systems. Overall, guidelines do not accurately reflect the situation of the elderly multimorbid, new strategies for managing multiple drug uses are needed to optimize prescribing in these patients. |
| publishDate |
2019 |
| dc.date.none.fl_str_mv |
2 2019-01-01 2019 2019-01-01 |
| dc.type.none.fl_str_mv |
Article http://purl.org/coar/resource_type/c_6501 VoR http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| dc.type.openaire.fl_str_mv |
info:eu-repo/semantics/article |
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article |
| dc.identifier.none.fl_str_mv |
https://ddd.uab.cat/record/223146 https://dx.doi.org/urn:doi:10.1186/s12875-019-0969-9 |
| url |
https://ddd.uab.cat/record/223146 https://dx.doi.org/urn:doi:10.1186/s12875-019-0969-9 |
| dc.language.none.fl_str_mv |
Inglés eng |
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Inglés |
| language |
eng |
| dc.rights.none.fl_str_mv |
open access http://purl.org/coar/access_right/c_abf2 https://creativecommons.org/licenses/by/4.0/ |
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info:eu-repo/semantics/openAccess |
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open access http://purl.org/coar/access_right/c_abf2 https://creativecommons.org/licenses/by/4.0/ |
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openAccess |
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application/pdf |
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reponame:Dipòsit Digital de Documents de la UAB instname:Universitat Autònoma de Barcelona |
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