Altered B-cell, plasma cell, and antibody immune profiles in blood of patients with systemic mastocytosis

[Background] Systemic mastocytosis (SM) is a heterogeneous disease characterized by an expansion of KIT-mutated constitutively activated mast cells (MCs) that release MC mediators, which might act on the tumor microenvironment including other immune cells.

Detalles Bibliográficos
Autores: Pérez-Pons, Alba, Henriques, Ana, Contreras-Sanfeliciano, Teresa, Jara-Acevedo, Maria, Navarro-Navarro, Paula, García-Montero, Andrés, Álvarez-Twose, Iván, Lecrevisse, Quentin, Fluxa, Rafael, Sánchez-Muñoz, Laura, Caldas, Carolina, Pozo, Julio, González-López, Óscar, Pérez-Andrés, Martin, Mayado, Andrea, Orfao, Alberto
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2025
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:dnet:digitalcsic_::8e69f0600612bb912ee83b2b4d8f4532
Acceso en línea:http://hdl.handle.net/10261/426238
https://api.elsevier.com/content/abstract/scopus_id/85209103000
Access Level:acceso abierto
Palabra clave:B lymphocyte
Immunoglobulin
Mast cell
Plasma cell
Systemic mastocytosis
Descripción
Sumario:[Background] Systemic mastocytosis (SM) is a heterogeneous disease characterized by an expansion of KIT-mutated constitutively activated mast cells (MCs) that release MC mediators, which might act on the tumor microenvironment including other immune cells.

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