Genetic identification of the central nucleus and other components of the central extended amygdala in chicken during development

In mammals, the central extended amygdala shows a highly complex organization, and is essential for animal survival due to its implication in fear responses. However, many aspects of its evolution are still unknown, and this structure is especially poorly understood in birds. The aim of this study w...

Descripción completa

Detalles Bibliográficos
Autores: Vicario Andrade, Alba, Abellán Ródenas, Antonio, Desfilis, Ester, Medina Hernández, Loreta Mª
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2014
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:10459.1/48761
Acceso en línea:https://doi.org/10.3389/fnana.2014.00090
http://hdl.handle.net/10459.1/48761
Access Level:acceso abierto
Palabra clave:Pollastres
Genètica animal
Chickens
Animal genetics
id ES_db76a891b63d9fdf3cdbeb5abe6cae01
oai_identifier_str oai:recercat.cat:10459.1/48761
network_acronym_str ES
network_name_str España
repository_id_str
spelling Genetic identification of the central nucleus and other components of the central extended amygdala in chicken during developmentVicario Andrade, AlbaAbellán Ródenas, AntonioDesfilis, EsterMedina Hernández, Loreta MªPollastresGenètica animalChickensAnimal geneticsIn mammals, the central extended amygdala shows a highly complex organization, and is essential for animal survival due to its implication in fear responses. However, many aspects of its evolution are still unknown, and this structure is especially poorly understood in birds. The aim of this study was to define the central extended amygdala in chicken, by means of a battery of region-specific transcription factors (Pax6, Islet1, Nkx2.1) and phenotypic markers that characterize these different subdivisions in mammals. Our results allowed the identification of at least six distinct subdivisions in the lateral part of the avian central extended amygdala: (1) capsular central subdivision; (2) a group of intercalated-like cell patches; (3) oval central nucleus; (4) peri-intrapeduncular (peri-INP) island field; (5) perioval zone; and (6) a rostral part of the subpallial extended amygdala. In addition, we identified three subdivisions of the laterodorsal bed nucleus of the stria terminalis (BSTLd) belonging to the medial region of the chicken central extended amygdala complex. Based on their genetic profile, cellular composition and apparent embryonic origin of the cells, we discuss the similarity of these different subdivisions of chicken with different parts of the mouse central amygdala and surrounding cell masses, including the intercalated amygdalar masses and the sublenticular part of the central extended amygdala. Most of the subdivisions include various subpopulations of cells that apparently originate in the dorsal striatal, ventral striatal, pallidal, and preoptic embryonic domains, reaching their final location by either radial or tangential migrations. Similarly to mammals, the central amygdala and BSTLd of chicken project to the hypothalamus, and include different neurons expressing proenkephalin, corticotropin-releasing factor, somatostatin or tyrosine hydroxylase, which may be involved in the control of different aspects of fear/anxiety-related behavior.Supported by a grant to Loreta Medina from the Spanish Ministry of Economy and Competitivity (MINECO) and Fondo Europeo de Desarrollo Regional (FEDER): grant no. BFU2012-33029. Alba Vicario had a predoctoral fellowship from the Spanish Ministry of Science and Innovation (reference no. BES-2010-038400).Frontiers Media S.A.2015201520142015info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://doi.org/10.3389/fnana.2014.00090http://hdl.handle.net/10459.1/48761http://hdl.handle.net/10459.1/48761reponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)Inglésinfo:eu-repo/grantAgreement/MICINN//BFU2012-33029info:eu-repo/grantAgreement/MICINN//BES-2010-038400Reproducció del document publicat a: https://doi.org/10.3389/fnana.2014.00090Frontiers In Neuroanatomy, 2014, vol. 8, num. 90, p. 1-23cc-by (c) Vicario Andrade, Alba et al., 2014info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/3.0/esoai:recercat.cat:10459.1/487612026-05-29T05:05:01Z
dc.title.none.fl_str_mv Genetic identification of the central nucleus and other components of the central extended amygdala in chicken during development
title Genetic identification of the central nucleus and other components of the central extended amygdala in chicken during development
spellingShingle Genetic identification of the central nucleus and other components of the central extended amygdala in chicken during development
Vicario Andrade, Alba
Pollastres
Genètica animal
Chickens
Animal genetics
title_short Genetic identification of the central nucleus and other components of the central extended amygdala in chicken during development
title_full Genetic identification of the central nucleus and other components of the central extended amygdala in chicken during development
title_fullStr Genetic identification of the central nucleus and other components of the central extended amygdala in chicken during development
title_full_unstemmed Genetic identification of the central nucleus and other components of the central extended amygdala in chicken during development
title_sort Genetic identification of the central nucleus and other components of the central extended amygdala in chicken during development
dc.creator.none.fl_str_mv Vicario Andrade, Alba
Abellán Ródenas, Antonio
Desfilis, Ester
Medina Hernández, Loreta Mª
author Vicario Andrade, Alba
author_facet Vicario Andrade, Alba
Abellán Ródenas, Antonio
Desfilis, Ester
Medina Hernández, Loreta Mª
author_role author
author2 Abellán Ródenas, Antonio
Desfilis, Ester
Medina Hernández, Loreta Mª
author2_role author
author
author
dc.subject.none.fl_str_mv Pollastres
Genètica animal
Chickens
Animal genetics
topic Pollastres
Genètica animal
Chickens
Animal genetics
description In mammals, the central extended amygdala shows a highly complex organization, and is essential for animal survival due to its implication in fear responses. However, many aspects of its evolution are still unknown, and this structure is especially poorly understood in birds. The aim of this study was to define the central extended amygdala in chicken, by means of a battery of region-specific transcription factors (Pax6, Islet1, Nkx2.1) and phenotypic markers that characterize these different subdivisions in mammals. Our results allowed the identification of at least six distinct subdivisions in the lateral part of the avian central extended amygdala: (1) capsular central subdivision; (2) a group of intercalated-like cell patches; (3) oval central nucleus; (4) peri-intrapeduncular (peri-INP) island field; (5) perioval zone; and (6) a rostral part of the subpallial extended amygdala. In addition, we identified three subdivisions of the laterodorsal bed nucleus of the stria terminalis (BSTLd) belonging to the medial region of the chicken central extended amygdala complex. Based on their genetic profile, cellular composition and apparent embryonic origin of the cells, we discuss the similarity of these different subdivisions of chicken with different parts of the mouse central amygdala and surrounding cell masses, including the intercalated amygdalar masses and the sublenticular part of the central extended amygdala. Most of the subdivisions include various subpopulations of cells that apparently originate in the dorsal striatal, ventral striatal, pallidal, and preoptic embryonic domains, reaching their final location by either radial or tangential migrations. Similarly to mammals, the central amygdala and BSTLd of chicken project to the hypothalamus, and include different neurons expressing proenkephalin, corticotropin-releasing factor, somatostatin or tyrosine hydroxylase, which may be involved in the control of different aspects of fear/anxiety-related behavior.
publishDate 2014
dc.date.none.fl_str_mv 2014
2015
2015
2015
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://doi.org/10.3389/fnana.2014.00090
http://hdl.handle.net/10459.1/48761
http://hdl.handle.net/10459.1/48761
url https://doi.org/10.3389/fnana.2014.00090
http://hdl.handle.net/10459.1/48761
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv info:eu-repo/grantAgreement/MICINN//BFU2012-33029
info:eu-repo/grantAgreement/MICINN//BES-2010-038400
Reproducció del document publicat a: https://doi.org/10.3389/fnana.2014.00090
Frontiers In Neuroanatomy, 2014, vol. 8, num. 90, p. 1-23
dc.rights.none.fl_str_mv cc-by (c) Vicario Andrade, Alba et al., 2014
info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by/3.0/es
rights_invalid_str_mv cc-by (c) Vicario Andrade, Alba et al., 2014
http://creativecommons.org/licenses/by/3.0/es
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Frontiers Media S.A.
publisher.none.fl_str_mv Frontiers Media S.A.
dc.source.none.fl_str_mv reponame:Recercat. Dipósit de la Recerca de Catalunya
instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname_str Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
reponame_str Recercat. Dipósit de la Recerca de Catalunya
collection Recercat. Dipósit de la Recerca de Catalunya
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869421677864026112
score 15,811543

Similares en LA Referencia