Highlights regarding prolactin in the dentate gyrus and hippocampus

[EN]Prolactin (PRL) is a pituitary hormone that has been typically related to lactogenesis in mammals. However, it has been described over 300 roles in the organism of vertebrae and its relationship with the central nervous system (CNS) is yet to be clarified. Mainly secreted by the pituitary gland,...

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Detalles Bibliográficos
Autores: Carretero Hernández, Marta, Catalano Iniesta, Leonardo, Blanco Barco, Enrique José, García Barrado, Josefa, Carretero González, José
Tipo de recurso: capítulo de libro
Estado:Versión publicada
Fecha de publicación:2022
País:España
Institución:Universidad de Salamanca (USAL)
Repositorio:GREDOS. Repositorio Institucional de la Universidad de Salamanca
OAI Identifier:oai:gredos.usal.es:10366/168410
Acceso en línea:http://hdl.handle.net/10366/168410
Access Level:acceso embargado
Palabra clave:Prolactin
Dentate gyrus
Hippocampus
Neurogenesis
Neuroprotection
Neuroplasticity
Learning
Memory
Dentate Gyrus
Neuroprotective Agents
fármacos neuroprotectores
aprendizaje
hipocampo
neurogénesis
prolactina
memoria
giro dentado
Descripción
Sumario:[EN]Prolactin (PRL) is a pituitary hormone that has been typically related to lactogenesis in mammals. However, it has been described over 300 roles in the organism of vertebrae and its relationship with the central nervous system (CNS) is yet to be clarified. Mainly secreted by the pituitary gland, the source of prolactin in the CNS remains unclear, where some experiments suggest active transport via an unknown carrier or, on the contrary, PRL being synthesized on the brain. So far, it seems to be involved with neurogenesis, neuroprotection, maternal behavior and cognitive processes in the hippocampus and dentate gyrus, among other regions.