Supercritical CO2 assisted synthesis and concentration of monoacylglycerides rich in omega-3 polyunsaturated fatty acids

Supercritical carbon dioxide (SC−CO2) has been used as solvent in the ethanolysis of fish oil rich with omega-3 polyunsaturated fatty acids (n-3 PUFAs) by Lipozyme 435. The effect of experimental conditions: initial ethanol-to-oil molar ratio (MR, 6:1-76:1), pressure (10–30 MPa), and temperature (32...

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Detalhes bibliográficos
Autores: Melgosa Gómez, Rodrigo, Sanz Díez, Mª Teresa, Benito Román, Oscar, Illera Gigante, Alba Ester, Beltrán Calvo, Sagrario
Formato: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2019
País:España
Recursos:Universidad de Burgos (UBU)
Repositorio:Repositorio Institucional de la Universidad de Burgos (RIUBU)
OAI Identifier:oai:riubu.ubu.es:10259/5077
Acesso em linha:http://hdl.handle.net/10259/5077
Access Level:acceso abierto
Palavra-chave:Omega 3
Lipase
Ethanolysis
Supercritical carbon dioxide
Supercritical fluid extraction
Ingeniería química
Chemical engineering
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spelling Supercritical CO2 assisted synthesis and concentration of monoacylglycerides rich in omega-3 polyunsaturated fatty acidsMelgosa Gómez, RodrigoSanz Díez, Mª TeresaBenito Román, OscarIllera Gigante, Alba EsterBeltrán Calvo, SagrarioOmega 3LipaseEthanolysisSupercritical carbon dioxideSupercritical fluid extractionIngeniería químicaChemical engineeringSupercritical carbon dioxide (SC−CO2) has been used as solvent in the ethanolysis of fish oil rich with omega-3 polyunsaturated fatty acids (n-3 PUFAs) by Lipozyme 435. The effect of experimental conditions: initial ethanol-to-oil molar ratio (MR, 6:1-76:1), pressure (10–30 MPa), and temperature (323–343 K) on the reaction performance has been studied. Experimental results have been fitted to a kinetic model based on a Ping Pong Bi Bi mechanism. High accumulation of monoacylglycerides (MAGs) has been observed in short reaction times (90 min at MR = 76:1, 10 MPa, 323 K). Subsequent purification of reaction products by supercritical fluid extraction (SFE) in the experimental range 10–28 MPa and 298–333 K yielded an extract rich with fatty acid ethyl esters (FAEE) (up to 99.46%wt.), and a raffinate with up to 82.25%wt. MAG and 49.5%wt. n-3 PUFAs.Spanish Government through MINECO and the European Regional Development Fund (ERDF) for financial support [grant number CTQ2012-39131-C02-01] and RM’s and AEI’s contracts [BES-2013-063937, CTQ2015-64396-R]. To Junta de Castilla y León and ERDF for financial support [grant number BU055U16] and ÓBR’s post-doctoral contract.Elsevier201920192021info:eu-repo/semantics/articleinfo:eu-repo/semantics/acceptedVersionapplication/pdfhttp://hdl.handle.net/10259/5077reponame:Repositorio Institucional de la Universidad de Burgos (RIUBU)instname:Universidad de Burgos (UBU)InglésJournal of CO2 Utilization. 2019, V. 31, p. 65-74https://doi.org/10.1016/j.jcou.2019.02.015info:eu-repo/grantAgreement/MINECO/CTQ2012-39131-C02-01/info:eu-repo/grantAgreement/JCyL/BU055U16/Attribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:riubu.ubu.es:10259/50772026-05-28T07:56:11Z
dc.title.none.fl_str_mv Supercritical CO2 assisted synthesis and concentration of monoacylglycerides rich in omega-3 polyunsaturated fatty acids
title Supercritical CO2 assisted synthesis and concentration of monoacylglycerides rich in omega-3 polyunsaturated fatty acids
spellingShingle Supercritical CO2 assisted synthesis and concentration of monoacylglycerides rich in omega-3 polyunsaturated fatty acids
Melgosa Gómez, Rodrigo
Omega 3
Lipase
Ethanolysis
Supercritical carbon dioxide
Supercritical fluid extraction
Ingeniería química
Chemical engineering
title_short Supercritical CO2 assisted synthesis and concentration of monoacylglycerides rich in omega-3 polyunsaturated fatty acids
title_full Supercritical CO2 assisted synthesis and concentration of monoacylglycerides rich in omega-3 polyunsaturated fatty acids
title_fullStr Supercritical CO2 assisted synthesis and concentration of monoacylglycerides rich in omega-3 polyunsaturated fatty acids
title_full_unstemmed Supercritical CO2 assisted synthesis and concentration of monoacylglycerides rich in omega-3 polyunsaturated fatty acids
title_sort Supercritical CO2 assisted synthesis and concentration of monoacylglycerides rich in omega-3 polyunsaturated fatty acids
dc.creator.none.fl_str_mv Melgosa Gómez, Rodrigo
Sanz Díez, Mª Teresa
Benito Román, Oscar
Illera Gigante, Alba Ester
Beltrán Calvo, Sagrario
author Melgosa Gómez, Rodrigo
author_facet Melgosa Gómez, Rodrigo
Sanz Díez, Mª Teresa
Benito Román, Oscar
Illera Gigante, Alba Ester
Beltrán Calvo, Sagrario
author_role author
author2 Sanz Díez, Mª Teresa
Benito Román, Oscar
Illera Gigante, Alba Ester
Beltrán Calvo, Sagrario
author2_role author
author
author
author
dc.subject.none.fl_str_mv Omega 3
Lipase
Ethanolysis
Supercritical carbon dioxide
Supercritical fluid extraction
Ingeniería química
Chemical engineering
topic Omega 3
Lipase
Ethanolysis
Supercritical carbon dioxide
Supercritical fluid extraction
Ingeniería química
Chemical engineering
description Supercritical carbon dioxide (SC−CO2) has been used as solvent in the ethanolysis of fish oil rich with omega-3 polyunsaturated fatty acids (n-3 PUFAs) by Lipozyme 435. The effect of experimental conditions: initial ethanol-to-oil molar ratio (MR, 6:1-76:1), pressure (10–30 MPa), and temperature (323–343 K) on the reaction performance has been studied. Experimental results have been fitted to a kinetic model based on a Ping Pong Bi Bi mechanism. High accumulation of monoacylglycerides (MAGs) has been observed in short reaction times (90 min at MR = 76:1, 10 MPa, 323 K). Subsequent purification of reaction products by supercritical fluid extraction (SFE) in the experimental range 10–28 MPa and 298–333 K yielded an extract rich with fatty acid ethyl esters (FAEE) (up to 99.46%wt.), and a raffinate with up to 82.25%wt. MAG and 49.5%wt. n-3 PUFAs.
publishDate 2019
dc.date.none.fl_str_mv 2019
2019
2021
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/acceptedVersion
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10259/5077
url http://hdl.handle.net/10259/5077
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Journal of CO2 Utilization. 2019, V. 31, p. 65-74
https://doi.org/10.1016/j.jcou.2019.02.015
info:eu-repo/grantAgreement/MINECO/CTQ2012-39131-C02-01/
info:eu-repo/grantAgreement/JCyL/BU055U16/
dc.rights.none.fl_str_mv Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositorio Institucional de la Universidad de Burgos (RIUBU)
instname:Universidad de Burgos (UBU)
instname_str Universidad de Burgos (UBU)
reponame_str Repositorio Institucional de la Universidad de Burgos (RIUBU)
collection Repositorio Institucional de la Universidad de Burgos (RIUBU)
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,300724

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