Deficits in early sensory and cognitive processing are related to phase and nonphase eeg activity in multiple sclerosis patients

Currently, there is scarce knowledge about the relation between spectral bands modulations and the basis of cognitive impairment in multiple sclerosis (MS). In this sense, analyzing the evoked or phase activity can confirm results from traditional event-related potential (ERP) studies. However, stud...

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Detalhes bibliográficos
Autores: Sarrias Arrabal, Esteban, Eichau, Sara, Galvao Carmona, Alejandro, Domínguez, Elvira, Izquierdo, Guillermo, Vázquez Marrufo, Manuel
Formato: artículo
Fecha de publicación:2021
País:España
Recursos:Universidad Loyola Andalucía
Repositorio:Brújula
OAI Identifier:oai:repositorio.uloyola.es:20.500.12412/4759
Acesso em linha:https://hdl.handle.net/20.500.12412/4759
Access Level:acceso abierto
Palavra-chave:Alpha
Oddball
EEG
Gamma
Multiple sclerosis
Evoked
Induced
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spelling Deficits in early sensory and cognitive processing are related to phase and nonphase eeg activity in multiple sclerosis patientsSarrias Arrabal, EstebanEichau, SaraGalvao Carmona, AlejandroDomínguez, ElviraIzquierdo, GuillermoVázquez Marrufo, ManuelAlphaOddballEEGGammaMultiple sclerosisEvokedInducedCurrently, there is scarce knowledge about the relation between spectral bands modulations and the basis of cognitive impairment in multiple sclerosis (MS). In this sense, analyzing the evoked or phase activity can confirm results from traditional event-related potential (ERP) studies. However, studying the induced or nonphase activity may be necessary to elucidate hidden compensatory or affected cognitive mechanisms. In this study, 30 remitting-relapsing multiple sclerosis patients and 30 healthy controls (HCs) matched in sociodemographic variables performed a visual oddball task. The main goal was to analyze phase and nonphase alpha and gamma bands by applying temporal spectral evolution (TSE) and its potential relation with cognitive impairment in these patients. The behavioural results showed slower reaction time and poorer accuracy in MS patients compared to controls. In contrast, the time-frequency analysis of electroencephalography (EEG) revealed a delay in latency and lower amplitude in MS patients in evoked and induced alpha compared to controls. With respect to the gamma band, there were no differences between the groups. In summary, MS patients showed deficits in early sensorial (evoked alpha activity) and cognitive processing (induced alpha activity in longer latencies), whereas the induced gamma band supported the hypothesis of its role in translation of attentional focus (induced activity) and did not show strong activity in this paradigm (visual oddball).2021info:eu-repo/semantics/articlehttps://hdl.handle.net/20.500.12412/4759reponame:Brújulainstname:Universidad Loyola AndalucíaIngléshttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:repositorio.uloyola.es:20.500.12412/47592026-06-24T12:48:37Z
dc.title.none.fl_str_mv Deficits in early sensory and cognitive processing are related to phase and nonphase eeg activity in multiple sclerosis patients
title Deficits in early sensory and cognitive processing are related to phase and nonphase eeg activity in multiple sclerosis patients
spellingShingle Deficits in early sensory and cognitive processing are related to phase and nonphase eeg activity in multiple sclerosis patients
Sarrias Arrabal, Esteban
Alpha
Oddball
EEG
Gamma
Multiple sclerosis
Evoked
Induced
title_short Deficits in early sensory and cognitive processing are related to phase and nonphase eeg activity in multiple sclerosis patients
title_full Deficits in early sensory and cognitive processing are related to phase and nonphase eeg activity in multiple sclerosis patients
title_fullStr Deficits in early sensory and cognitive processing are related to phase and nonphase eeg activity in multiple sclerosis patients
title_full_unstemmed Deficits in early sensory and cognitive processing are related to phase and nonphase eeg activity in multiple sclerosis patients
title_sort Deficits in early sensory and cognitive processing are related to phase and nonphase eeg activity in multiple sclerosis patients
dc.creator.none.fl_str_mv Sarrias Arrabal, Esteban
Eichau, Sara
Galvao Carmona, Alejandro
Domínguez, Elvira
Izquierdo, Guillermo
Vázquez Marrufo, Manuel
author Sarrias Arrabal, Esteban
author_facet Sarrias Arrabal, Esteban
Eichau, Sara
Galvao Carmona, Alejandro
Domínguez, Elvira
Izquierdo, Guillermo
Vázquez Marrufo, Manuel
author_role author
author2 Eichau, Sara
Galvao Carmona, Alejandro
Domínguez, Elvira
Izquierdo, Guillermo
Vázquez Marrufo, Manuel
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Alpha
Oddball
EEG
Gamma
Multiple sclerosis
Evoked
Induced
topic Alpha
Oddball
EEG
Gamma
Multiple sclerosis
Evoked
Induced
description Currently, there is scarce knowledge about the relation between spectral bands modulations and the basis of cognitive impairment in multiple sclerosis (MS). In this sense, analyzing the evoked or phase activity can confirm results from traditional event-related potential (ERP) studies. However, studying the induced or nonphase activity may be necessary to elucidate hidden compensatory or affected cognitive mechanisms. In this study, 30 remitting-relapsing multiple sclerosis patients and 30 healthy controls (HCs) matched in sociodemographic variables performed a visual oddball task. The main goal was to analyze phase and nonphase alpha and gamma bands by applying temporal spectral evolution (TSE) and its potential relation with cognitive impairment in these patients. The behavioural results showed slower reaction time and poorer accuracy in MS patients compared to controls. In contrast, the time-frequency analysis of electroencephalography (EEG) revealed a delay in latency and lower amplitude in MS patients in evoked and induced alpha compared to controls. With respect to the gamma band, there were no differences between the groups. In summary, MS patients showed deficits in early sensorial (evoked alpha activity) and cognitive processing (induced alpha activity in longer latencies), whereas the induced gamma band supported the hypothesis of its role in translation of attentional focus (induced activity) and did not show strong activity in this paradigm (visual oddball).
publishDate 2021
dc.date.none.fl_str_mv 2021
dc.type.none.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/20.500.12412/4759
url https://hdl.handle.net/20.500.12412/4759
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv http://creativecommons.org/licenses/by-nc-nd/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv reponame:Brújula
instname:Universidad Loyola Andalucía
instname_str Universidad Loyola Andalucía
reponame_str Brújula
collection Brújula
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,811543

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