The effectiveness of non-invasive brain stimulation in enhancing lower extremity function in children with spastic cerebral palsy: Protocol for a systematic review and meta-analysis

Non-invasive brain stimulation (NIBS1) techniques have emerged as a promising non pharmacological adjunct to neurorehabilitation. Children with Cerebral Palsy (CP2) exhibit al tered cortical excitability, and while CP remains incurable, physiotherapy combined with other interventions is essential fo...

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Detalles Bibliográficos
Autores: Arumí Trujillo, Clàudia, Verdejo Amengual, Francisco José, Martínez-Navarro, Oriol, Vink, Jord J.T., Valenzuela Pascual, Francesc
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2025
País:España
Institución:Universitat de Lleida (UdL)
Repositorio:Repositori Obert UdL
OAI Identifier:oai:repositori.udl.cat:10459.1/467208
Acceso en línea:https://doi.org/10.1016/j.mex.2024.103141
https://hdl.handle.net/10459.1/467208
Access Level:acceso abierto
Palabra clave:Transcranial Magnetic Stimulation
Transcranial Direct Current Stimulation
Cerebral Palsy
Cortical excitability
Motor skills
Muscle spasticity
Descripción
Sumario:Non-invasive brain stimulation (NIBS1) techniques have emerged as a promising non pharmacological adjunct to neurorehabilitation. Children with Cerebral Palsy (CP2) exhibit al tered cortical excitability, and while CP remains incurable, physiotherapy combined with other interventions is essential for managing motor dysfunction. Although some studies have examined NIBS using various stimulation parameters, there is limited evidence regarding its effects on the lower extremities and optimal administration protocols. This review aims to evaluate the effec tiveness of NIBS techniques, such as transcranial direct current stimulation (tDCS3) and repetitive transcranial magnetic stimulation (rTMS4), for the treatment of motor function in spastic cerebral palsy, specifically in the lower extremity. A systematic search will be conducted in databases in cluding MEDLINE, CINAHL Plus, EMBASE, Scopus, ISI Web of Science, and the Cochrane Central Register of Controlled Trials. The search strategy will follow the PICO framework (Participants, Intervention, Comparison, Outcomes), focusing on randomized controlled trials (RCTs). Two in dependent reviewers will manage screening, selection, data extraction, risk of bias assessment, and grading of evidence. This review will provide key insights into the effectiveness of NIBS for lower-extremity function in children with spastic CP, guiding future research and clinical appli cations.