Fish and seafood consumption during pregnancy and the risk of asthma and allergic rhinitis in childhood: a pooled analysis of 18 European and US birth cohorts

Background: It has been suggested that prenatal exposure to n-3 long-chain fatty acids protects against asthma and other allergy-related diseases later in childhood. The extent to which fish intake in pregnancy protects against child asthma and rhinitis symptoms remains unclear. We aimed to assess w...

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Autores: Stratakis N, Roumeliotaki T, Oken E, Ballester F, Barros H, Basterrechea M, Cordier S, de Groot R, den Dekker HT, Duijts L, Eggesbø M, Pia Fantini M, Forastiere F, Gehring U, Gielen M, Gori D, Govarts E, Inskip HM, Iszatt N, Jansen M, Kelleher C, Mehegan J, Moltó-Puigmartí C, Mommers M, Oliveira A, Olsen SF, Pelé F, Pizzi C, Porta D, Richiardi L, Rifas-Shiman SL, Robinson SM, Schoeters G, Strøm M, Sunyer J, Thijs C, Vrijheid M, Vrijkotte TG, Wijga AH, Kogevinas M, Zeegers MP, Chatzi L
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2017
País:España
Institución:Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
Repositorio:r-FISABIO. Repositorio Institucional de Producción Científica
OAI Identifier:oai:fisabio.fundanetsuite.com:p1892
Acceso en línea:https://fisabio.portalinvestigacion.com/publicaciones/1892
Access Level:acceso abierto
Palabra clave:Wheezing
asthma
allergic rhinitis
children
fish
seafood
pregnancy
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spelling Fish and seafood consumption during pregnancy and the risk of asthma and allergic rhinitis in childhood: a pooled analysis of 18 European and US birth cohortsStratakis NRoumeliotaki TOken EBallester FBarros HBasterrechea MCordier Sde Groot Rden Dekker HTDuijts LEggesbø MPia Fantini MForastiere FGehring UGielen MGori DGovarts EInskip HMIszatt NJansen MKelleher CMehegan JMoltó-Puigmartí CMommers MOliveira AOlsen SFPelé FPizzi CPorta DRichiardi LRifas-Shiman SLRobinson SMSchoeters GStrøm MSunyer JThijs CVrijheid MVrijkotte TGWijga AHKogevinas MZeegers MPChatzi LWheezingasthmaallergic rhinitischildrenfishseafoodpregnancyBackground: It has been suggested that prenatal exposure to n-3 long-chain fatty acids protects against asthma and other allergy-related diseases later in childhood. The extent to which fish intake in pregnancy protects against child asthma and rhinitis symptoms remains unclear. We aimed to assess whether fish and seafood consumption in pregnancy is associated with childhood wheeze, asthma and allergic rhinitis. Methods: We pooled individual data from 60 774 mother-child pairs participating in 18 European and US birth cohort studies. Information on wheeze, asthma and allergic rhinitis prevalence was collected using validated questionnaires. The time periods of interest were: infancy (0-2 years), preschool age (3-4 years), and school age (5-8 years). We used multivariable generalized models to assess associations of fish and seafood (other than fish) consumption during pregnancy with child respiratory outcomes in cohort-specific analyses, with subsequent random-effects meta-analyses. Results: The median fish consumption during pregnancy ranged from 0.44 times/week in The Netherlands to 4.46 times/week in Spain. Maternal fish intake during pregnancy was not associated with offspring wheeze symptoms in any age group nor with the risk of child asthma [adjusted meta-analysis relative risk (RR) per 1-time/week = 1.01, 95% confidence interval 0.97-1.05)] and allergic rhinitis at school age (RR = 1.01, 0.99-1.03). These results were consistently found in further analyses by type of fish and seafood consumption and in sensitivity analyses. Conclusion: We found no evidence supporting a protective association of fish and seafood consumption during pregnancy with offspring symptoms of wheeze, asthma and allergic rhinitis from infancy to mid childhood.OXFORD UNIV PRESS2017info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://fisabio.portalinvestigacion.com/publicaciones/1892INTERNATIONAL JOURNAL OF EPIDEMIOLOGYISSN: 03005771ISSNe: 14643685reponame:r-FISABIO. Repositorio Institucional de Producción Científicainstname:Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)Inglésinfo:eu-repo/semantics/openAccessoai:fisabio.fundanetsuite.com:p18922026-06-11T12:45:17Z
dc.title.none.fl_str_mv Fish and seafood consumption during pregnancy and the risk of asthma and allergic rhinitis in childhood: a pooled analysis of 18 European and US birth cohorts
title Fish and seafood consumption during pregnancy and the risk of asthma and allergic rhinitis in childhood: a pooled analysis of 18 European and US birth cohorts
spellingShingle Fish and seafood consumption during pregnancy and the risk of asthma and allergic rhinitis in childhood: a pooled analysis of 18 European and US birth cohorts
Stratakis N
Wheezing
asthma
allergic rhinitis
children
fish
seafood
pregnancy
title_short Fish and seafood consumption during pregnancy and the risk of asthma and allergic rhinitis in childhood: a pooled analysis of 18 European and US birth cohorts
title_full Fish and seafood consumption during pregnancy and the risk of asthma and allergic rhinitis in childhood: a pooled analysis of 18 European and US birth cohorts
title_fullStr Fish and seafood consumption during pregnancy and the risk of asthma and allergic rhinitis in childhood: a pooled analysis of 18 European and US birth cohorts
title_full_unstemmed Fish and seafood consumption during pregnancy and the risk of asthma and allergic rhinitis in childhood: a pooled analysis of 18 European and US birth cohorts
title_sort Fish and seafood consumption during pregnancy and the risk of asthma and allergic rhinitis in childhood: a pooled analysis of 18 European and US birth cohorts
dc.creator.none.fl_str_mv Stratakis N
Roumeliotaki T
Oken E
Ballester F
Barros H
Basterrechea M
Cordier S
de Groot R
den Dekker HT
Duijts L
Eggesbø M
Pia Fantini M
Forastiere F
Gehring U
Gielen M
Gori D
Govarts E
Inskip HM
Iszatt N
Jansen M
Kelleher C
Mehegan J
Moltó-Puigmartí C
Mommers M
Oliveira A
Olsen SF
Pelé F
Pizzi C
Porta D
Richiardi L
Rifas-Shiman SL
Robinson SM
Schoeters G
Strøm M
Sunyer J
Thijs C
Vrijheid M
Vrijkotte TG
Wijga AH
Kogevinas M
Zeegers MP
Chatzi L
author Stratakis N
author_facet Stratakis N
Roumeliotaki T
Oken E
Ballester F
Barros H
Basterrechea M
Cordier S
de Groot R
den Dekker HT
Duijts L
Eggesbø M
Pia Fantini M
Forastiere F
Gehring U
Gielen M
Gori D
Govarts E
Inskip HM
Iszatt N
Jansen M
Kelleher C
Mehegan J
Moltó-Puigmartí C
Mommers M
Oliveira A
Olsen SF
Pelé F
Pizzi C
Porta D
Richiardi L
Rifas-Shiman SL
Robinson SM
Schoeters G
Strøm M
Sunyer J
Thijs C
Vrijheid M
Vrijkotte TG
Wijga AH
Kogevinas M
Zeegers MP
Chatzi L
author_role author
author2 Roumeliotaki T
Oken E
Ballester F
Barros H
Basterrechea M
Cordier S
de Groot R
den Dekker HT
Duijts L
Eggesbø M
Pia Fantini M
Forastiere F
Gehring U
Gielen M
Gori D
Govarts E
Inskip HM
Iszatt N
Jansen M
Kelleher C
Mehegan J
Moltó-Puigmartí C
Mommers M
Oliveira A
Olsen SF
Pelé F
Pizzi C
Porta D
Richiardi L
Rifas-Shiman SL
Robinson SM
Schoeters G
Strøm M
Sunyer J
Thijs C
Vrijheid M
Vrijkotte TG
Wijga AH
Kogevinas M
Zeegers MP
Chatzi L
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Wheezing
asthma
allergic rhinitis
children
fish
seafood
pregnancy
topic Wheezing
asthma
allergic rhinitis
children
fish
seafood
pregnancy
description Background: It has been suggested that prenatal exposure to n-3 long-chain fatty acids protects against asthma and other allergy-related diseases later in childhood. The extent to which fish intake in pregnancy protects against child asthma and rhinitis symptoms remains unclear. We aimed to assess whether fish and seafood consumption in pregnancy is associated with childhood wheeze, asthma and allergic rhinitis. Methods: We pooled individual data from 60 774 mother-child pairs participating in 18 European and US birth cohort studies. Information on wheeze, asthma and allergic rhinitis prevalence was collected using validated questionnaires. The time periods of interest were: infancy (0-2 years), preschool age (3-4 years), and school age (5-8 years). We used multivariable generalized models to assess associations of fish and seafood (other than fish) consumption during pregnancy with child respiratory outcomes in cohort-specific analyses, with subsequent random-effects meta-analyses. Results: The median fish consumption during pregnancy ranged from 0.44 times/week in The Netherlands to 4.46 times/week in Spain. Maternal fish intake during pregnancy was not associated with offspring wheeze symptoms in any age group nor with the risk of child asthma [adjusted meta-analysis relative risk (RR) per 1-time/week = 1.01, 95% confidence interval 0.97-1.05)] and allergic rhinitis at school age (RR = 1.01, 0.99-1.03). These results were consistently found in further analyses by type of fish and seafood consumption and in sensitivity analyses. Conclusion: We found no evidence supporting a protective association of fish and seafood consumption during pregnancy with offspring symptoms of wheeze, asthma and allergic rhinitis from infancy to mid childhood.
publishDate 2017
dc.date.none.fl_str_mv 2017
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://fisabio.portalinvestigacion.com/publicaciones/1892
url https://fisabio.portalinvestigacion.com/publicaciones/1892
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv OXFORD UNIV PRESS
publisher.none.fl_str_mv OXFORD UNIV PRESS
dc.source.none.fl_str_mv INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
ISSN: 03005771
ISSNe: 14643685
reponame:r-FISABIO. Repositorio Institucional de Producción Científica
instname:Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
instname_str Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
reponame_str r-FISABIO. Repositorio Institucional de Producción Científica
collection r-FISABIO. Repositorio Institucional de Producción Científica
repository.name.fl_str_mv
repository.mail.fl_str_mv
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