Reducing leads, enhancing wearable practicality: a comparative study of 3-lead vs. 12-lead ECG classification

Inspired by recent advances in clinical research and the growing adoption of wearable ECG devices, this study explores the feasibility of using reduced-lead ECGs for automated detection of heart anomalies using deep learning, providing a more accessible and cost-effective alternative to traditional...

Descripción completa

Detalles Bibliográficos
Autores: González-Cabeza, Sergio, Sanz-Guerrero, Mario, Piñuel, Luis, Buelga Suárez, Mauro, Alonso Salinas, Gonzalo Luis, Díaz-Vicente, Marian, Recas Piorno, Joaquín
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2025
País:España
Institución:Universidad Pública de Navarra
Repositorio:Academica-e. Repositorio Institucional de la Universidad Pública de Navarra
OAI Identifier:oai:academica-e.unavarra.es:2454/55353
Acceso en línea:https://hdl.handle.net/2454/55353
Access Level:acceso abierto
Palabra clave:Deep learning
Electrocardiography
One-vs-All classification
Reduced-lead ECG
Transfer learning
Descripción
Sumario:Inspired by recent advances in clinical research and the growing adoption of wearable ECG devices, this study explores the feasibility of using reduced-lead ECGs for automated detection of heart anomalies using deep learning, providing a more accessible and cost-effective alternative to traditional 12-lead ECGs. This research adapts and evaluates a state-of-the-art 12-lead deep learning model (from Ribeiro et al. [1]) for 3-lead configurations. The 12-lead ECG model architecture was trained from scratch on the public database PTB-XL. It was then modified to use 3 leads by only changing the input layer. Despite a 75% reduction in input data, the 3-lead model showed only a subtle 3% performance drop. To address this gap, the 3-lead model was further optimized using a novel strategy that combines transfer learning and a One-vs-All classification approach. Using PTB-XL's five-class setup (normal vs. four pathologies: myocardial infarction, ST/T change, conduction disturbance, and hypertrophy), we report the micro-averaged F1-score across all test samples. The new optimized 3-lead model achieves a global (micro-averaged) F1-score of 77% (vs. 78% for the 12-lead model). These findings highlight the potential of simplified and cost-effective reduced-lead classification models to deliver near-equivalent diagnostic accuracy. This advancement could democratize access to early cardiac diagnostics, particularly in resource-limited settings.