One-year outcome following biological or mechanical valve replacement for infective endocarditis

Background: Nearly half of patients require cardiac surgery during the acute phase of infective endocarditis (IE). We describe the characteristics of patients according to the type of valve replacement (mechanical or biological), and examine whether the type of prosthesis was associated with in-hosp...

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Autores: Heras, Magda, Almela, M. (Manel), Armero, Yolanda, Azqueta, Manuel, Castañeda, Ximena, Cervera, Carlos, Rio, Ana del, Falces Salvador, Carles, García de la Mària, Cristina, Fita, Guillermina, Gatell, José M., Llopis Pérez, Jaime, Marco Reverté, Francesc, Mestres Lucio, Carlos-Alberto, Miró Meda, José M. (José María), 1956-, Moreno Camacho, Ma. Asunción, Ninot i Sugrañes, Josep Maria, Paré, Carlos, Pericàs, Juan M., Ramirez, José, Rovira, Irene, Sitges Carreño, Marta, Anguera Camós, Ignasi, Endocarditis Prospective Cohort Study (ICE-PCS) Investigators
Formato: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2015
País:España
Recursos:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/127956
Acesso em linha:https://hdl.handle.net/2445/127956
Access Level:acceso abierto
Palavra-chave:Endocarditis
Cirurgia
Pròtesis valvulars cardíaques
Surgery
Heart valve prosthesis
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repository_id_str
spelling One-year outcome following biological or mechanical valve replacement for infective endocarditisHeras, MagdaAlmela, M. (Manel)Armero, YolandaAzqueta, ManuelCastañeda, XimenaCervera, CarlosRio, Ana delFalces Salvador, CarlesGarcía de la Mària, CristinaFita, GuillerminaGatell, José M.Llopis Pérez, JaimeMarco Reverté, FrancescMestres Lucio, Carlos-AlbertoMiró Meda, José M. (José María), 1956-Moreno Camacho, Ma. AsunciónNinot i Sugrañes, Josep MariaParé, CarlosPericàs, Juan M.Ramirez, JoséRovira, IreneSitges Carreño, MartaAnguera Camós, IgnasiEndocarditis Prospective Cohort Study (ICE-PCS) InvestigatorsEndocarditisCirurgiaPròtesis valvulars cardíaquesEndocarditisSurgeryHeart valve prosthesisBackground: Nearly half of patients require cardiac surgery during the acute phase of infective endocarditis (IE). We describe the characteristics of patients according to the type of valve replacement (mechanical or biological), and examine whether the type of prosthesis was associated with in-hospital and 1-year mortality. Methods and results: Among 5591 patients included in the International Collaboration on Endocarditis Prospective Cohort Study, 1467 patients with definite IE were operated on during the active phase and had a biological (37%) or mechanical (63%) valve replacement. Patients who received bioprostheses were older (62 vs 54 years), more often had a history of cancer (9% vs 6%), and had moderate or severe renal disease (9% vs 4%); proportion of health care-associated IE was higher (26% vs 17%); intracardiac abscesses were more frequent (30% vs 23%). In-hospital and 1-year death rates were higher in the bioprosthesis group, 20.5% vs 14.0% (p = 0.0009) and 25.3% vs 16.6% (p < .0001), respectively. In multivariable analysis, mechanical prostheses were less commonly implanted in older patients (odds ratio: 0.64 for every 10 years), and in patients with a history of cancer (0.72), but were more commonly implanted in mitral position (1.60). Bioprosthesis was independently associated with 1-year mortality (hazard ratio: 1.298). Conclusions: Patients with IE who receive a biological valve replacement have significant differences in clinical characteristics compared to patients who receive a mechanical prosthesis. Biological valve replacement is independently associated with a higher in-hospital and 1-year mortality, a result which is possibly related to patient characteristics rather than valve dysfunction.Elsevier B.V.2019201920152019info:eu-repo/semantics/articleinfo:eu-repo/semantics/acceptedVersion7 p.application/pdfhttps://hdl.handle.net/2445/127956Articles publicats en revistes (Medicina)reponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésVersió postprint del document publicat a: https://doi.org/10.1016/j.ijcard.2014.10.125International Journal of Cardiology, 2015, vol. 178, p. 117-123https://doi.org/10.1016/j.ijcard.2014.10.125(c) Elsevier B.V., 2015info:eu-repo/semantics/openAccessoai:recercat.cat:2445/1279562026-05-29T05:05:01Z
dc.title.none.fl_str_mv One-year outcome following biological or mechanical valve replacement for infective endocarditis
title One-year outcome following biological or mechanical valve replacement for infective endocarditis
spellingShingle One-year outcome following biological or mechanical valve replacement for infective endocarditis
Heras, Magda
Endocarditis
Cirurgia
Pròtesis valvulars cardíaques
Endocarditis
Surgery
Heart valve prosthesis
title_short One-year outcome following biological or mechanical valve replacement for infective endocarditis
title_full One-year outcome following biological or mechanical valve replacement for infective endocarditis
title_fullStr One-year outcome following biological or mechanical valve replacement for infective endocarditis
title_full_unstemmed One-year outcome following biological or mechanical valve replacement for infective endocarditis
title_sort One-year outcome following biological or mechanical valve replacement for infective endocarditis
dc.creator.none.fl_str_mv Heras, Magda
Almela, M. (Manel)
Armero, Yolanda
Azqueta, Manuel
Castañeda, Ximena
Cervera, Carlos
Rio, Ana del
Falces Salvador, Carles
García de la Mària, Cristina
Fita, Guillermina
Gatell, José M.
Llopis Pérez, Jaime
Marco Reverté, Francesc
Mestres Lucio, Carlos-Alberto
Miró Meda, José M. (José María), 1956-
Moreno Camacho, Ma. Asunción
Ninot i Sugrañes, Josep Maria
Paré, Carlos
Pericàs, Juan M.
Ramirez, José
Rovira, Irene
Sitges Carreño, Marta
Anguera Camós, Ignasi
Endocarditis Prospective Cohort Study (ICE-PCS) Investigators
author Heras, Magda
author_facet Heras, Magda
Almela, M. (Manel)
Armero, Yolanda
Azqueta, Manuel
Castañeda, Ximena
Cervera, Carlos
Rio, Ana del
Falces Salvador, Carles
García de la Mària, Cristina
Fita, Guillermina
Gatell, José M.
Llopis Pérez, Jaime
Marco Reverté, Francesc
Mestres Lucio, Carlos-Alberto
Miró Meda, José M. (José María), 1956-
Moreno Camacho, Ma. Asunción
Ninot i Sugrañes, Josep Maria
Paré, Carlos
Pericàs, Juan M.
Ramirez, José
Rovira, Irene
Sitges Carreño, Marta
Anguera Camós, Ignasi
Endocarditis Prospective Cohort Study (ICE-PCS) Investigators
author_role author
author2 Almela, M. (Manel)
Armero, Yolanda
Azqueta, Manuel
Castañeda, Ximena
Cervera, Carlos
Rio, Ana del
Falces Salvador, Carles
García de la Mària, Cristina
Fita, Guillermina
Gatell, José M.
Llopis Pérez, Jaime
Marco Reverté, Francesc
Mestres Lucio, Carlos-Alberto
Miró Meda, José M. (José María), 1956-
Moreno Camacho, Ma. Asunción
Ninot i Sugrañes, Josep Maria
Paré, Carlos
Pericàs, Juan M.
Ramirez, José
Rovira, Irene
Sitges Carreño, Marta
Anguera Camós, Ignasi
Endocarditis Prospective Cohort Study (ICE-PCS) Investigators
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Endocarditis
Cirurgia
Pròtesis valvulars cardíaques
Endocarditis
Surgery
Heart valve prosthesis
topic Endocarditis
Cirurgia
Pròtesis valvulars cardíaques
Endocarditis
Surgery
Heart valve prosthesis
description Background: Nearly half of patients require cardiac surgery during the acute phase of infective endocarditis (IE). We describe the characteristics of patients according to the type of valve replacement (mechanical or biological), and examine whether the type of prosthesis was associated with in-hospital and 1-year mortality. Methods and results: Among 5591 patients included in the International Collaboration on Endocarditis Prospective Cohort Study, 1467 patients with definite IE were operated on during the active phase and had a biological (37%) or mechanical (63%) valve replacement. Patients who received bioprostheses were older (62 vs 54 years), more often had a history of cancer (9% vs 6%), and had moderate or severe renal disease (9% vs 4%); proportion of health care-associated IE was higher (26% vs 17%); intracardiac abscesses were more frequent (30% vs 23%). In-hospital and 1-year death rates were higher in the bioprosthesis group, 20.5% vs 14.0% (p = 0.0009) and 25.3% vs 16.6% (p < .0001), respectively. In multivariable analysis, mechanical prostheses were less commonly implanted in older patients (odds ratio: 0.64 for every 10 years), and in patients with a history of cancer (0.72), but were more commonly implanted in mitral position (1.60). Bioprosthesis was independently associated with 1-year mortality (hazard ratio: 1.298). Conclusions: Patients with IE who receive a biological valve replacement have significant differences in clinical characteristics compared to patients who receive a mechanical prosthesis. Biological valve replacement is independently associated with a higher in-hospital and 1-year mortality, a result which is possibly related to patient characteristics rather than valve dysfunction.
publishDate 2015
dc.date.none.fl_str_mv 2015
2019
2019
2019
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/acceptedVersion
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/127956
url https://hdl.handle.net/2445/127956
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Versió postprint del document publicat a: https://doi.org/10.1016/j.ijcard.2014.10.125
International Journal of Cardiology, 2015, vol. 178, p. 117-123
https://doi.org/10.1016/j.ijcard.2014.10.125
dc.rights.none.fl_str_mv (c) Elsevier B.V., 2015
info:eu-repo/semantics/openAccess
rights_invalid_str_mv (c) Elsevier B.V., 2015
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 7 p.
application/pdf
dc.publisher.none.fl_str_mv Elsevier B.V.
publisher.none.fl_str_mv Elsevier B.V.
dc.source.none.fl_str_mv Articles publicats en revistes (Medicina)
reponame:Recercat. Dipósit de la Recerca de Catalunya
instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname_str Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
reponame_str Recercat. Dipósit de la Recerca de Catalunya
collection Recercat. Dipósit de la Recerca de Catalunya
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15.812429

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