Acceleration of 3D feature-enhancing noise filtering in hybrid CPU/GPU systems

FlowDenoising is a new approach to noise reduction in biological volumes obtained with three-dimensional electron microscopy (3DEM). Its abilities to enhance the structural features stem from the fact that an anisotropic Gaussian filtering is steered according to the local structures. To this end, t...

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Detalles Bibliográficos
Autores: González-Ruiz, Vicente, Moreno, J. J., Fernández, José Jesús
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2024
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/360190
Acceso en línea:http://hdl.handle.net/10261/360190
Access Level:acceso abierto
Palabra clave:High-performance computing
GPU
CPU
Heterogeneous computing
Noise fltering
3D electron microscopy
Optical fow
Descripción
Sumario:FlowDenoising is a new approach to noise reduction in biological volumes obtained with three-dimensional electron microscopy (3DEM). Its abilities to enhance the structural features stem from the fact that an anisotropic Gaussian filtering is steered according to the local structures. To this end, the Optical Flow (OF) among consecutive slices is estimated, which is the most computationally expensive step in this approach. In this article, a hybrid CPU/GPU implementation of FlowDenoising is introduced and evaluated. It exploits parallel computing by distributing the workload among multiple cores and takes advantage of the massive processing in GPUs to accelerate the OF estimation. The hybrid implementation provides remarkable speed-up factors and an important reduction of the processing time, which is particularly relevant for the denoising of huge volumes typically found in 3DEM.