When breast cancer spreads below the belt - A case of rectal metastasis from invasive lobular carcinoma

We present the case of a 62-year-old woman diagnosed in 2014 with invasive luminal A lobular carcinoma (ILC) of the breast (T3N0M0). She underwent a modified radical mastectomy, followed by radiotherapy and five years of endocrine therapy with letrozole. In 2021, therapy was discontinued due to musc...

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Detalles Bibliográficos
Autores: Puente-Monserrat J, Pérez-Santiago L, Terrádez-Mas L, Pla-Martí V, Casado-Rodrigo D, Martín-Arévalo J, Moro-Valdezate D, García-Botello SA
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2025
País:España
Institución:INCLIVA
Repositorio:r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
OAI Identifier:oai:incliva.fundanetsuite.com:p20180
Acceso en línea:https://incliva.portalinvestigacion.com/publicaciones/20180
Access Level:acceso abierto
Palabra clave:Breast cancer
Gastrointestinal metastasis
Lobular carcinoma
Rectal metastasis
Descripción
Sumario:We present the case of a 62-year-old woman diagnosed in 2014 with invasive luminal A lobular carcinoma (ILC) of the breast (T3N0M0). She underwent a modified radical mastectomy, followed by radiotherapy and five years of endocrine therapy with letrozole. In 2021, therapy was discontinued due to musculoskeletal side effects. Seven years after diagnosis, the patient developed symptoms of partial bowel obstruction, along with a progressive rise in CA15.3 levels during oncological follow-up. Multiple diagnostic evaluations-including colonoscopies, enteric MRI, and PET scan-yielded normal results, initially suggesting inflammatory bowel disease.