Prospective randomized trial of enoxaparin, pentoxifylline and ursodeoxycholic acid for prevention of radiation-induced liver toxicity

The post-therapeutic application of PTX, UDCA and low-dose LMWH significantly reduced the extent and incidence fRILI at 6 weeks after radiotherapy. The development of subsequent fRILI at 12 weeks (4 weeks after cessation of PTX, UDCA and LMWH during weeks 1-8) in the treatment group was comparable t...

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Detalles Bibliográficos
Autores: Seidensticker, M. (Max)|||/items/5365aab8-55e0-458c-85f0-ff43e3b91270, Seidensticker, R. (Ricarda)|||/items/3e2a5f6f-e93e-4023-9b16-d4758eedee24, Damn, R. (Robert)|||/items/136f4b65-d97d-492b-82a2-eb63a6852128, Mohnike, K. (Konrad)|||/items/d1f3aa88-15e0-4c61-8fc5-cbef6006117c, Pech, M. (Maciej)|||/items/3952e467-7f56-4131-afac-c7864104471f, Sangro-Gómez-Acebo, B.C. (Bruno Carlos)|||/items/594bbdbb-046a-4ab2-878c-cb4fe577af49, Hass, P. (Peter)|||/items/e0a43701-56fc-4fcd-b085-b88665f604d5, Wust, P. (Peter)|||/items/add579d9-7849-4efc-9f58-9f603ea91287, Kropf, S. (Siegfried)|||/items/9fa1b602-eda7-4c04-bc05-c822c9ab4f0c, Gademann, G. (Günther)|||/items/361091c1-cc98-4ec0-b547-cf551ac07683, Ricke, J. (Jeans)|||/items/3bfc1d9c-b91e-4e2f-99ca-959622b33e38
Tipo de recurso: artículo
Fecha de publicación:2014
País:España
Institución:Universidad de Navarra
Repositorio:Dadun. Depósito Académico Digital de la Universidad de Navarra
Idioma:inglés
OAI Identifier:oai:dadun.unav.edu:10171/38240
Acceso en línea:https://hdl.handle.net/10171/38240
Access Level:acceso abierto
Palabra clave:Liver
Pentoxifylline and ursodeoxycholic acid
Descripción
Sumario:The post-therapeutic application of PTX, UDCA and low-dose LMWH significantly reduced the extent and incidence fRILI at 6 weeks after radiotherapy. The development of subsequent fRILI at 12 weeks (4 weeks after cessation of PTX, UDCA and LMWH during weeks 1-8) in the treatment group was comparable to the control group thus supporting the observation that the agents mitigated fRILI.