Identification of Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome-associated DNA methylation patterns

Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a complex condition involving multiple organ systems and characterized by persistent/relapsing debilitating fatigue, immune dysfunction, neurological problems, and other symptoms not curable for at least 6 months. Disruption of DNA methy...

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Detalles Bibliográficos
Autores: Trivedi, Malav S., Oltra García, Elisa Josefa, Sarria, Leonor, Rose, Natasha, Beljanski, Vladimir, Fletcher, Mary Ann, Klimas, Nancy G., Nathanson, Lubov
Tipo de recurso: artículo
Fecha de publicación:2018
País:España
Institución:Universidad Católica de Valencia San Vicente Mártir
Repositorio:RIUCV. Repositorio de la Universidad Católica de Valencia San Vicente Mártir
Idioma:inglés
OAI Identifier:oai:riucv.ucv.es:20.500.12466/4583
Acceso en línea:http://hdl.handle.net/20.500.12466/4583
Access Level:acceso abierto
Palabra clave:Myalgic Encephalomyelitis
Chronic Fatigue Syndrome
DNA
32 Ciencias Médicas
Descripción
Sumario:Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a complex condition involving multiple organ systems and characterized by persistent/relapsing debilitating fatigue, immune dysfunction, neurological problems, and other symptoms not curable for at least 6 months. Disruption of DNA methylation patterns has been tied to various immune and neurological diseases; however, its status in ME/CFS remains uncertain. Our study aimed at identifying changes in the DNA methylation patterns that associate with ME/CFS.

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