Proteomics for Clinical Assessment of Kidney Disease

Kidney disease is one of the fastest growing causes of death worldwide, disclosing an unmet clinical need for early diagnosis and optimized risk stratification that allows high risk patient selection for clinical trials and for more intensive nephroprotective interventions in the clinic. The current...

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Detalhes bibliográficos
Autor: Ortiz Arduán, Alberto
Tipo de documento: artigo
Data de publicação:2019
País:España
Recursos:Universidad Autónoma de Madrid
Repositório:Biblos-e Archivo. Repositorio Institucional de la UAM
Idioma:inglês
OAI Identifier:oai:repositorio.uam.es:10486/688635
Acesso em linha:http://hdl.handle.net/10486/688635
https://dx.doi.org/10.1002/prca.201900004
Access Level:Acceso aberto
Palavra-chave:Chronic kidney disease
Early diagnosis
Proteomics
Clinical applications
Medicina
Descrição
Resumo:Kidney disease is one of the fastest growing causes of death worldwide, disclosing an unmet clinical need for early diagnosis and optimized risk stratification that allows high risk patient selection for clinical trials and for more intensive nephroprotective interventions in the clinic. The current issue of PROTEOMICS—Clinical Applications contains four manuscripts that explore different aspects of clinical proteomics implementation in the context of acute kidney injury, chronic kidney disease and, more specifically, diabetic kidney disease, and kidney transplantation from a diagnostic and risk stratification point of view. Overall, the evidence discussed suggests that chronic kidney disease is an example where clinical proteomics has become a valuable tool ready for clinical implementation, expected to have a major impact in patient management.