Biodegradable and biocompatible collagen-based hybrid materials for force sensing applications

With the aim of replacing synthetic macromolecules by biological macromolecules for advanced applications, collagen films were produced with two different ionic liquids (ILs), choline dihydrogen phosphate ([Ch][DHP]) and choline serinate ([Ch][Seri]), added in order to modulate the electrical respon...

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Detalles Bibliográficos
Autores: Andonegui San Martín, Mireia, Meira, Rafaela M., Correia, Daniela M., Pereira, Nelson, Costa, Carlos M., Lanceros Méndez, Senentxu, De la Caba Ciriza, María Coro, Guerrero Manso, Pedro Manuel
Tipo de recurso: artículo
Fecha de publicación:2024
País:España
Institución:Universidad del País Vasco
Repositorio:Addi. Archivo Digital para la Docencia y la Investigación
OAI Identifier:oai:addi.ehu.eus:10810/71147
Acceso en línea:http://hdl.handle.net/10810/71147
Access Level:acceso abierto
Palabra clave:collagen
electrical response
pressure sensor
Descripción
Sumario:With the aim of replacing synthetic macromolecules by biological macromolecules for advanced applications, collagen films were produced with two different ionic liquids (ILs), choline dihydrogen phosphate ([Ch][DHP]) and choline serinate ([Ch][Seri]), added in order to modulate the electrical responses. The films were prepared by casting, varying IL content between 0 and 6 wt%. The morphology and thermal properties of the resulting films were found to be independent of both IL type and content. However, the highest direct curret (d.c.) electrical conductivity (1.4 ×10 8 S⋅cm1) was achieved for collagen films containing 3 wt% [Ch][DHP]. Furthermore, it was demonstrated that IL/collagen films were non-cytotoxic, with cell activity values exceeding 70 %. These collagen films were proven to be suitable for force sensing applications, displaying excellent sensitivity and stability upon repeated testing.