Immunothrombosis: molecular aspects and new therapeutic perspectives

Thromboinflammation or immunothrombosis is a concept that explains the existing link between coagulation and inflammatory response present in many situations, such as sepsis, venous thromboembolism, or COVID-19 associated coagulopathy. The purpose of this review is to provide an overview of the curr...

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Detalles Bibliográficos
Autores: Marcos-Jubilar, M. (María)|||/items/f684e8b6-f081-47fd-80ac-632a9e41d5d6, Lecumberri-Villamediana, R. (Ramón)|||/items/d804c113-76a8-47fb-85ad-0f01acbe605a, Páramo-Fernández, J.A. (José Antonio)|||/items/8c56baa6-2a43-4836-b91b-4eed15be3c96
Tipo de recurso: artículo
Fecha de publicación:2023
País:España
Institución:Universidad de Navarra
Repositorio:Dadun. Depósito Académico Digital de la Universidad de Navarra
Idioma:inglés
OAI Identifier:oai:dadun.unav.edu:10171/65928
Acceso en línea:https://hdl.handle.net/10171/65928
Access Level:acceso abierto
Palabra clave:Immunothrombosis
Thromboinflammation
Tissue factor
Descripción
Sumario:Thromboinflammation or immunothrombosis is a concept that explains the existing link between coagulation and inflammatory response present in many situations, such as sepsis, venous thromboembolism, or COVID-19 associated coagulopathy. The purpose of this review is to provide an overview of the current data regarding the mechanisms involved in immunothrombosis in order to understand the new therapeutic strategies focused in reducing thrombotic risk by controlling the inflammation.