Inclusion complexes of citronella oil with ß-Cyclodextrin for controlled release in biofunctional textiles
Biofunctional textiles with integrated drug-delivery systems can help in the fight against vector-borne diseases. The use of repellent agents derived from plants and oils is an alternative to DEET (N,N-diethyl-m-methylbenzamide), which has disadvantages that include toxic reactions and skin damage....
| Autores: | , , , |
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| Tipo de recurso: | artículo |
| Fecha de publicación: | 2018 |
| País: | España |
| Institución: | Universitat Politècnica de Catalunya (UPC) |
| Repositorio: | UPCommons. Portal del coneixement obert de la UPC |
| Idioma: | inglés |
| OAI Identifier: | oai:upcommons.upc.edu:2117/125546 |
| Acceso en línea: | https://hdl.handle.net/2117/125546 https://dx.doi.org/10.3390/polym10121324 |
| Access Level: | acceso abierto |
| Palabra clave: | Textile finishing Biopolymers Esterification Drug delivery systems Cotton textiles Textile fibers, Synthetic Polyester fibers Cotton Polyester Drug delivery Teixits i tèxtils -- Acabat Fibres tèxtils sintètiques Fibres de poliester Biopolímers Esterificació Medicaments -- Modes d'administració Teixits i tèxtils -- Innovacions tecnològiques Àrees temàtiques de la UPC::Enginyeria tèxtil::Teixits |
| Sumario: | Biofunctional textiles with integrated drug-delivery systems can help in the fight against vector-borne diseases. The use of repellent agents derived from plants and oils is an alternative to DEET (N,N-diethyl-m-methylbenzamide), which has disadvantages that include toxic reactions and skin damage. However, some researchers report that oils can be ineffective due to reasons related to uncontrolled release. In this work, the mechanism of control of citronella oil (OC) complexed with b-cyclodextrin (bCD) on cotton (COT) and polyester (PES) textiles was investigated. The results obtained reveal that finishing cotton and polyester with b-cyclodextrin complexes allows for control of the release mechanism of the drug from the fabric. To assess the complexes formed, optical microscopy, SEM, and FTIR were carried out; the yield of complex formation was obtained by spectroscopy in the ultraviolet region; and controlled release was performed in vitro. Oil complexation with bCD had a yield of 63.79%, and it was observed that the release, which was in seconds, moved to hours when applied to fabrics. The results show that complexes seem to be a promising basis when it comes to immobilizing oils and controlling their release when modified with chemical crosslinking agents |
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