Management of wet age-related macular degeneration in Spain: Challenges for treat and extend implementation in routine clinical practice

Purpose. To ascertain wet AMD (wAMD) management patterns in Spain. Methods. A two-round Delphi study conducted through a questionnaire-based survey designed from literature review and validated by an independent Steering Committee. Results. Forty-nine retina specialists experienced in wAMD participa...

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Autores: García-Layana, A., García-Arumí, J., Figueroa, M. S., Arias Barquet, L., Ruiz Moreno, José María, Monclus-Arbona, L., The Spanish AMD Multicenter Group
Tipo de recurso: artículo
Fecha de publicación:2019
País:España
Institución:Universidad Autónoma de Madrid
Repositorio:Biblos-e Archivo. Repositorio Institucional de la UAM
Idioma:inglés
OAI Identifier:oai:repositorio.uam.es:10486/691293
Acceso en línea:http://hdl.handle.net/10486/691293
https://dx.doi.org/10.1155/2019/9821509
Access Level:acceso abierto
Palabra clave:Macular degeneration
Retina specialists
Anti-VEGF administration
Proactive treatment patterns
Medicina
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spelling Management of wet age-related macular degeneration in Spain: Challenges for treat and extend implementation in routine clinical practiceGarcía-Layana, A.García-Arumí, J.Figueroa, M. S.Arias Barquet, L.Ruiz Moreno, José MaríaMonclus-Arbona, L.The Spanish AMD Multicenter GroupMacular degenerationRetina specialistsAnti-VEGF administrationProactive treatment patternsMedicinaPurpose. To ascertain wet AMD (wAMD) management patterns in Spain. Methods. A two-round Delphi study conducted through a questionnaire-based survey designed from literature review and validated by an independent Steering Committee. Results. Forty-nine retina specialists experienced in wAMD participated by answering the two-round study questionnaire. Retina specialists are the main responsible for wAMD diagnosis and monitoring, including visits and associated procedures, with a median time per visit of 15 minutes. Standard treatment strategies are based on anti-VEGF administration, including standard loading dose administration followed by maintenance with aflibercept or ranibizumab (81% of patients). Although treat and extend (T&E) dosing strategy is considered as optimal for wAMD management (78% of the panelists), the main routine healthcare limitations (i.e., visits overload, reduced staff, short visit time, coordination issues, lack of facilities) conduct to self-defined “flexible” strategies, based on T&E and pro-re-nata (PRN) protocols. Conclusion. Proactive treatment patterns (T&E) are the preferred ones by the retina specialists in Spain. However, their proper implementation is difficult due to healthcare resource limitations, as well as organisation and logistic issues. .e use of anti-VEGF agents with longer duration of action could facilitate the use of strict T&E approaches according to routine clinical practicesThe study has been sponsored by Bayer Hispania S.L. LogisticsHindawiDepartamento de CirugíaFacultad de Medicina20192019-09-30research articlehttp://purl.org/coar/resource_type/c_2df8fbb1VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10486/691293https://dx.doi.org/10.1155/2019/9821509reponame:Biblos-e Archivo. Repositorio Institucional de la UAMinstname:Universidad Autónoma de MadridInglésengopen accesshttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessoai:repositorio.uam.es:10486/6912932026-06-23T12:46:27Z
dc.title.none.fl_str_mv Management of wet age-related macular degeneration in Spain: Challenges for treat and extend implementation in routine clinical practice
title Management of wet age-related macular degeneration in Spain: Challenges for treat and extend implementation in routine clinical practice
spellingShingle Management of wet age-related macular degeneration in Spain: Challenges for treat and extend implementation in routine clinical practice
García-Layana, A.
Macular degeneration
Retina specialists
Anti-VEGF administration
Proactive treatment patterns
Medicina
title_short Management of wet age-related macular degeneration in Spain: Challenges for treat and extend implementation in routine clinical practice
title_full Management of wet age-related macular degeneration in Spain: Challenges for treat and extend implementation in routine clinical practice
title_fullStr Management of wet age-related macular degeneration in Spain: Challenges for treat and extend implementation in routine clinical practice
title_full_unstemmed Management of wet age-related macular degeneration in Spain: Challenges for treat and extend implementation in routine clinical practice
title_sort Management of wet age-related macular degeneration in Spain: Challenges for treat and extend implementation in routine clinical practice
dc.creator.none.fl_str_mv García-Layana, A.
García-Arumí, J.
Figueroa, M. S.
Arias Barquet, L.
Ruiz Moreno, José María
Monclus-Arbona, L.
The Spanish AMD Multicenter Group
author García-Layana, A.
author_facet García-Layana, A.
García-Arumí, J.
Figueroa, M. S.
Arias Barquet, L.
Ruiz Moreno, José María
Monclus-Arbona, L.
The Spanish AMD Multicenter Group
author_role author
author2 García-Arumí, J.
Figueroa, M. S.
Arias Barquet, L.
Ruiz Moreno, José María
Monclus-Arbona, L.
The Spanish AMD Multicenter Group
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Departamento de Cirugía
Facultad de Medicina
dc.subject.none.fl_str_mv Macular degeneration
Retina specialists
Anti-VEGF administration
Proactive treatment patterns
Medicina
topic Macular degeneration
Retina specialists
Anti-VEGF administration
Proactive treatment patterns
Medicina
description Purpose. To ascertain wet AMD (wAMD) management patterns in Spain. Methods. A two-round Delphi study conducted through a questionnaire-based survey designed from literature review and validated by an independent Steering Committee. Results. Forty-nine retina specialists experienced in wAMD participated by answering the two-round study questionnaire. Retina specialists are the main responsible for wAMD diagnosis and monitoring, including visits and associated procedures, with a median time per visit of 15 minutes. Standard treatment strategies are based on anti-VEGF administration, including standard loading dose administration followed by maintenance with aflibercept or ranibizumab (81% of patients). Although treat and extend (T&E) dosing strategy is considered as optimal for wAMD management (78% of the panelists), the main routine healthcare limitations (i.e., visits overload, reduced staff, short visit time, coordination issues, lack of facilities) conduct to self-defined “flexible” strategies, based on T&E and pro-re-nata (PRN) protocols. Conclusion. Proactive treatment patterns (T&E) are the preferred ones by the retina specialists in Spain. However, their proper implementation is difficult due to healthcare resource limitations, as well as organisation and logistic issues. .e use of anti-VEGF agents with longer duration of action could facilitate the use of strict T&E approaches according to routine clinical practices
publishDate 2019
dc.date.none.fl_str_mv 2019
2019-09-30
dc.type.none.fl_str_mv research article
http://purl.org/coar/resource_type/c_2df8fbb1
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/10486/691293
https://dx.doi.org/10.1155/2019/9821509
url http://hdl.handle.net/10486/691293
https://dx.doi.org/10.1155/2019/9821509
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Hindawi
publisher.none.fl_str_mv Hindawi
dc.source.none.fl_str_mv reponame:Biblos-e Archivo. Repositorio Institucional de la UAM
instname:Universidad Autónoma de Madrid
instname_str Universidad Autónoma de Madrid
reponame_str Biblos-e Archivo. Repositorio Institucional de la UAM
collection Biblos-e Archivo. Repositorio Institucional de la UAM
repository.name.fl_str_mv
repository.mail.fl_str_mv
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