| Sumario: | Supplementary material: Table S1. Alpha-diversity is expressed as Observed Species, Shannon, and Simpson indexes. Letters denote statistically significant differences between samples and times. Differences regarding the control that are statistically significant (p < 0.05) are marked in gray. Table S2. Genus level. Mean relative abundances (%) and standard deviation. Only genus with a mean relative abundance >0.5% and/or statistically significant were considered. Statistical differences (p-adjust < 0.05) regarding the control and PLAg/PLAm for each volunteer are highlighted, in gray if they appear only for one volunteer or in orange if they are common to at least two volunteers. Table S3. Concentration (µM) of short-chain fatty acids (SCFAs) at different colonic fermentation times. Table S4. Lactate concentration (µg/mL) at different colonic fermentation times. Table S5. Predicted bacterial pathways present in PLAm and PLAg samples from colonic fermentation simulations for the three volunteers. Only statistically different features comparing to control (q-value<0.05) and with a mean relative abundance >0.01% are shown. met. = metabolism. deg. = degradation. Table S6. Predicted bacterial genes (i.e., enzymes and proteins) present in PLAm and PLAg samples from colonic fermentation simulations for the three volunteers. Only statistically different features comparing to control (q-value<0.05). and with a mean relative abundance >0.01% are shown. Figure S1. Beta-diversity plots of the three volunteers (0, 24, 48, and 72 h) and the different conditions tested (control, PLAg, and PLAm).
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