Long non-coding RNAs and their potential role as biomarkers in inflammatory bowel disease

Inflammatory bowel disease is a chronic inflammatory disease that encompasses entities such as Crohn’s disease and ulcerative colitis. Its incidence has risen in newly industrialised countries over time, turning it into a global disease. Lately, studies on inflammatory bowel disease have focused on...

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Detalles Bibliográficos
Autores: Ortega Moreno, Lorena, Chaparro Sánchez, María, Pérez Gisbert, Francisco Javier
Tipo de recurso: artículo
Fecha de publicación:2024
País:España
Institución:Universidad Autónoma de Madrid
Repositorio:Biblos-e Archivo. Repositorio Institucional de la UAM
Idioma:inglés
OAI Identifier:oai:dnet:biblosearchi::b1e276f902223b8bcc50c78e174149f2
Acceso en línea:https://hdl.handle.net/10486/756780
https://dx.doi.org/10.3390/ijms25168808
Access Level:acceso abierto
Palabra clave:long non-coding RNAs
inflammatory bowel disease
Crohn’s disease
ulcerative colitis
biomarkers
Medicina
Descripción
Sumario:Inflammatory bowel disease is a chronic inflammatory disease that encompasses entities such as Crohn’s disease and ulcerative colitis. Its incidence has risen in newly industrialised countries over time, turning it into a global disease. Lately, studies on inflammatory bowel disease have focused on finding non-invasive and specific biomarkers. Long non-coding RNAs may play a role in the pathophysiology of inflammatory bowel disease and therefore they may be considered as potential biomarkers for this disease. In the present article, we review information in the literature on the relationship between long non-coding RNAs and inflammatory bowel disease. We especially focus on understanding the potential function of these RNAs as non-invasive biomarkers, providing information that may be helpful for future studies in the field