Myokine/Adipokine Response to “Aerobic” Exercise: Is It Just a Matter of Exercise Load?

Purpose: Exercise health benefits are partly mediated by exertional changes in several myokines/adipokines. This study aimed to compare the acute response of some of these biomarkers to aerobic exercise performed at the intensity corresponding to the maximum fat oxidation rate (FATmax) or the “anaer...

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Authors: He, Zi-Hong, Tian, Ye, Valenzuela Ruiz, Pedro Luis, Huang, Chuanye, Zhao, Jiexiu, Hong, Ping, He, Zilin, Yin, Shuhui, Lucía Mulas, Alejandro
Format: article
Publication Date:2019
Country:España
Institution:Universidad Europea (UEM)
Repository:ABACUS. Repositorio de Producción Científica
Language:English
OAI Identifier:oai:abacus.universidadeuropea.com:11268/8009
Online Access:http://hdl.handle.net/11268/8009
Access Level:Open access
Keyword:Fisiología del ejercicio
Bioquímica
Deporte
Efectos fisiológicos
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spelling Myokine/Adipokine Response to “Aerobic” Exercise: Is It Just a Matter of Exercise Load?He, Zi-HongTian, YeValenzuela Ruiz, Pedro LuisHuang, ChuanyeZhao, JiexiuHong, PingHe, ZilinYin, ShuhuiLucía Mulas, AlejandroFisiología del ejercicioBioquímicaDeporteEfectos fisiológicosBioquímicaPurpose: Exercise health benefits are partly mediated by exertional changes in several myokines/adipokines. This study aimed to compare the acute response of some of these biomarkers to aerobic exercise performed at the intensity corresponding to the maximum fat oxidation rate (FATmax) or the “anaerobic” threshold (AT). Methods: Following a cross-over, counterbalanced design, 14 healthy untrained men (23 ± 1 years) performed a 45-min exercise bout at their FATmax or AT intensity (been previously determined through incremental exercise tests). The concentration of interleukin (IL)-15, follistatin, myostatin, fibroblast-growth factor (FGF)-21, irisin, resistin, and omentin was measured at baseline and 0, 1, 3, 24, 48, and 72 h post-exercise. Results: AT exercise was performed at a higher intensity (85 ± 8 vs. 52 ± 14% of maximal oxygen uptake [VO2 max], p < 0.001) and induced a higher energy expenditure (p < 0.001) than FATmax, whereas a greater fat oxidation was observed in the latter (p < 0.001). A higher peak response of FGF-21 (+90%, p < 0.01) and follistatin (+49%, p < 0.05) was found after AT-exercise, as well as a trend toward a higher peak level of omentin (+13%, p = 0.071) and a greater decrease in resistin (−16%, p = 0.073). Conclusion: Increasing exercise load (from FATmax to AT) results in a higher response of FGF-21, follistatin and omentin to aerobic exercise, with the subsequent potential cardiometabolic benefits. No effects were, however, observed on the remainder of biomarkers. Future research should address if manipulating other exercise variables (e.g., type, frequency) can promote a higher myokine/adipokine response.20192019-06-0620192019-01-0120192019-01-01journal articlehttp://purl.org/coar/resource_type/c_6501info:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/11268/8009reponame:ABACUS. Repositorio de Producción Científicainstname:Universidad Europea (UEM)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Attribution-NonCommercial-NoDerivatives 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:abacus.universidadeuropea.com:11268/80092026-06-11T12:41:27Z
dc.title.none.fl_str_mv Myokine/Adipokine Response to “Aerobic” Exercise: Is It Just a Matter of Exercise Load?
title Myokine/Adipokine Response to “Aerobic” Exercise: Is It Just a Matter of Exercise Load?
spellingShingle Myokine/Adipokine Response to “Aerobic” Exercise: Is It Just a Matter of Exercise Load?
He, Zi-Hong
Fisiología del ejercicio
Bioquímica
Deporte
Efectos fisiológicos
Bioquímica
title_short Myokine/Adipokine Response to “Aerobic” Exercise: Is It Just a Matter of Exercise Load?
title_full Myokine/Adipokine Response to “Aerobic” Exercise: Is It Just a Matter of Exercise Load?
title_fullStr Myokine/Adipokine Response to “Aerobic” Exercise: Is It Just a Matter of Exercise Load?
title_full_unstemmed Myokine/Adipokine Response to “Aerobic” Exercise: Is It Just a Matter of Exercise Load?
title_sort Myokine/Adipokine Response to “Aerobic” Exercise: Is It Just a Matter of Exercise Load?
dc.creator.none.fl_str_mv He, Zi-Hong
Tian, Ye
Valenzuela Ruiz, Pedro Luis
Huang, Chuanye
Zhao, Jiexiu
Hong, Ping
He, Zilin
Yin, Shuhui
Lucía Mulas, Alejandro
author He, Zi-Hong
author_facet He, Zi-Hong
Tian, Ye
Valenzuela Ruiz, Pedro Luis
Huang, Chuanye
Zhao, Jiexiu
Hong, Ping
He, Zilin
Yin, Shuhui
Lucía Mulas, Alejandro
author_role author
author2 Tian, Ye
Valenzuela Ruiz, Pedro Luis
Huang, Chuanye
Zhao, Jiexiu
Hong, Ping
He, Zilin
Yin, Shuhui
Lucía Mulas, Alejandro
author2_role author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv
dc.subject.none.fl_str_mv Fisiología del ejercicio
Bioquímica
Deporte
Efectos fisiológicos
Bioquímica
topic Fisiología del ejercicio
Bioquímica
Deporte
Efectos fisiológicos
Bioquímica
description Purpose: Exercise health benefits are partly mediated by exertional changes in several myokines/adipokines. This study aimed to compare the acute response of some of these biomarkers to aerobic exercise performed at the intensity corresponding to the maximum fat oxidation rate (FATmax) or the “anaerobic” threshold (AT). Methods: Following a cross-over, counterbalanced design, 14 healthy untrained men (23 ± 1 years) performed a 45-min exercise bout at their FATmax or AT intensity (been previously determined through incremental exercise tests). The concentration of interleukin (IL)-15, follistatin, myostatin, fibroblast-growth factor (FGF)-21, irisin, resistin, and omentin was measured at baseline and 0, 1, 3, 24, 48, and 72 h post-exercise. Results: AT exercise was performed at a higher intensity (85 ± 8 vs. 52 ± 14% of maximal oxygen uptake [VO2 max], p < 0.001) and induced a higher energy expenditure (p < 0.001) than FATmax, whereas a greater fat oxidation was observed in the latter (p < 0.001). A higher peak response of FGF-21 (+90%, p < 0.01) and follistatin (+49%, p < 0.05) was found after AT-exercise, as well as a trend toward a higher peak level of omentin (+13%, p = 0.071) and a greater decrease in resistin (−16%, p = 0.073). Conclusion: Increasing exercise load (from FATmax to AT) results in a higher response of FGF-21, follistatin and omentin to aerobic exercise, with the subsequent potential cardiometabolic benefits. No effects were, however, observed on the remainder of biomarkers. Future research should address if manipulating other exercise variables (e.g., type, frequency) can promote a higher myokine/adipokine response.
publishDate 2019
dc.date.none.fl_str_mv 2019
2019-06-06
2019
2019-01-01
2019
2019-01-01
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/11268/8009
url http://hdl.handle.net/11268/8009
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 Internacional
http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 Internacional
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:ABACUS. Repositorio de Producción Científica
instname:Universidad Europea (UEM)
instname_str Universidad Europea (UEM)
reponame_str ABACUS. Repositorio de Producción Científica
collection ABACUS. Repositorio de Producción Científica
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,301603

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