Influence of fluid dynamic conditions on 1,3-propanediol production from glycerol by Shimwellia blattae: Carbon flux and cell response

The fluid dynamic conditions play a key role in the development and scaling up of bioprocesses. In aerobic cultures, oxygen is an essential substrate for microbial growth, production and culture maintenance; an effective gas-liquid transfer must be achieved. Changes in fluid dynamics due to stirrer...

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Detalles Bibliográficos
Autores: Rodríguez, Alberto, Ripoll, Vanessa, Santos, Victoria E., Gómez, Emilio, García-Ochoa Soria, Félix
Tipo de recurso: artículo
Fecha de publicación:2017
País:España
Institución:Universidad Complutense de Madrid (UCM)
Repositorio:Docta Complutense
Idioma:inglés
OAI Identifier:oai:docta.ucm.es:20.500.14352/17682
Acceso en línea:https://hdl.handle.net/20.500.14352/17682
Access Level:acceso abierto
Palabra clave:66.0
2
3-butanediol
Raoultella terrigena
fluid dynamics
hydrodynamic and oxidative stress
oxygen mass transfer coefficient
stirred tank bioreactor
Ingeniería química
3303 Ingeniería y Tecnología Químicas
Descripción
Sumario:The fluid dynamic conditions play a key role in the development and scaling up of bioprocesses. In aerobic cultures, oxygen is an essential substrate for microbial growth, production and culture maintenance; an effective gas-liquid transfer must be achieved. Changes in fluid dynamics due to stirrer speed can affect negatively to the culture, causing hydrodynamic stress (increasing shear stress) or oxidative stress (by an increase of available oxygen in the liquid phase).