Comment: Humoral and T-cell Immunities to SARS-CoV-2 Vaccines: Safety, Efficacy, and Challenges in Autoimmune Neurology

With the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) messenger RNA (mRNA)vaccinations, we have been witnessing a new era in vaccinology because these vaccines do not contain viral proteins but mRNA or viral vectors that instruct the cells to make viralspecific protective antibodies....

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Detalhes bibliográficos
Autores: Dalakas, Marinos C., Dalmau Obrador, Josep
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2023
País:España
Recursos:Universidad de Barcelona
Repositorio:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/209126
Acesso em linha:https://hdl.handle.net/2445/209126
Access Level:acceso abierto
Palavra-chave:COVID-19
Vacunes
Vaccines
Descrição
Resumo:With the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) messenger RNA (mRNA)vaccinations, we have been witnessing a new era in vaccinology because these vaccines do not contain viral proteins but mRNA or viral vectors that instruct the cells to make viralspecific protective antibodies. To effectively fight SARS-CoV-2 infection, however, these vaccines need to induce both humoral and cell-mediated immune responses, with antibodies that block viral replication and viral-specific T cells that kill viral-infected cells and generate antibodyproducing plasma cells and long-lived memory cells.