Characterization of neurogenic niches and radial glial cells in the telencephalon of sharks: Comparative aspects and evolutionary implications
The telencephalon experiments many morphological and cytoarchitecture changes along evolution. For gaining understanding of the evolution of the telencephalon, we have analyzed the spatio-temporal pattern of several neurogenic and radial glial markers during telencephalic development and adulthood i...
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| Tipo de recurso: | tesis doctoral |
| Fecha de publicación: | 2018 |
| País: | España |
| Institución: | Universidad de Santiago de Compostela (USC) |
| Repositorio: | Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela |
| Idioma: | inglés |
| OAI Identifier: | oai:minerva.usc.gal:10347/17903 |
| Acceso en línea: | http://hdl.handle.net/10347/17903 |
| Access Level: | acceso abierto |
| Palabra clave: | Materias::Investigación::24 Ciencias de la vida::2409 Genética::240991 Genética del desarrollo Materias::Investigación::24 Ciencias de la vida::2401 Biología animal (zoología)::240105 Desarrollo animal |
| Sumario: | The telencephalon experiments many morphological and cytoarchitecture changes along evolution. For gaining understanding of the evolution of the telencephalon, we have analyzed the spatio-temporal pattern of several neurogenic and radial glial markers during telencephalic development and adulthood in the cathsark, Scyliorhinus canicula. We have found a highly conserved expression pattern of neurogenic markers and morphologically and molecularly heterogeneous radial glial cells. In addition, we have investigated whether these markers and radial glial cells are present along the entire life of sharks and constitute the basis of adult neurogenesis in basal vertebrates. We have explored the evolutionary implications of the main similarities and differences we found with respect to other vertebrates. |
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