Acute respiratory distress syndrome: does histology matter?

Kao et al. have reported in Critical Care the histological findings of 101 patients with acute respiratory distress syndrome (ARDS) undergoing open lung biopsy. Diffuse alveolar damage (DAD), the histological hallmark of ARDS, was present in only 56.4 % of cases. The presence of DAD was associated w...

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Detalles Bibliográficos
Autores: Lorente Balanza, José Ángel, Ballén Barragán, A., Herrero, Raquel, Esteban, Andrés
Tipo de recurso: artículo
Fecha de publicación:2015
País:España
Institución:Universidad Europea (UEM)
Repositorio:ABACUS. Repositorio de Producción Científica
Idioma:inglés
OAI Identifier:oai:abacus.universidadeuropea.com:11268/6125
Acceso en línea:http://hdl.handle.net/11268/6125
Access Level:acceso abierto
Palabra clave:Síndrome de distrés respiratorio
Histología
Aparato respiratorio
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spelling Acute respiratory distress syndrome: does histology matter?Lorente Balanza, José ÁngelBallén Barragán, A.Herrero, RaquelEsteban, AndrésSíndrome de distrés respiratorioHistologíaAparato respiratorioKao et al. have reported in Critical Care the histological findings of 101 patients with acute respiratory distress syndrome (ARDS) undergoing open lung biopsy. Diffuse alveolar damage (DAD), the histological hallmark of ARDS, was present in only 56.4 % of cases. The presence of DAD was associated with higher mortality. Evidence from this and other studies indicates that the clinical criteria for the diagnosis of ARDS identify DAD in only about half of the cases. On the contrary, there is evidence that the clinical course and outcome of ARDS differs in patients with DAD and in patients without DAD. The discovery of biomarkers for the physiological (increased alveolocapillary permeability) or histological (DAD) hallmarks of ARDS is thus of paramount importance.20162016-12-2320152015-01-0120152015-01-01journal articlehttp://purl.org/coar/resource_type/c_6501info:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/11268/6125reponame:ABACUS. Repositorio de Producción Científicainstname:Universidad Europea (UEM)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Reconocimiento 3.0 Españahttps://creativecommons.org/licenses/by/3.0/es/info:eu-repo/semantics/openAccessoai:abacus.universidadeuropea.com:11268/61252026-06-11T12:41:27Z
dc.title.none.fl_str_mv Acute respiratory distress syndrome: does histology matter?
title Acute respiratory distress syndrome: does histology matter?
spellingShingle Acute respiratory distress syndrome: does histology matter?
Lorente Balanza, José Ángel
Síndrome de distrés respiratorio
Histología
Aparato respiratorio
title_short Acute respiratory distress syndrome: does histology matter?
title_full Acute respiratory distress syndrome: does histology matter?
title_fullStr Acute respiratory distress syndrome: does histology matter?
title_full_unstemmed Acute respiratory distress syndrome: does histology matter?
title_sort Acute respiratory distress syndrome: does histology matter?
dc.creator.none.fl_str_mv Lorente Balanza, José Ángel
Ballén Barragán, A.
Herrero, Raquel
Esteban, Andrés
author Lorente Balanza, José Ángel
author_facet Lorente Balanza, José Ángel
Ballén Barragán, A.
Herrero, Raquel
Esteban, Andrés
author_role author
author2 Ballén Barragán, A.
Herrero, Raquel
Esteban, Andrés
author2_role author
author
author
dc.contributor.none.fl_str_mv
dc.subject.none.fl_str_mv Síndrome de distrés respiratorio
Histología
Aparato respiratorio
topic Síndrome de distrés respiratorio
Histología
Aparato respiratorio
description Kao et al. have reported in Critical Care the histological findings of 101 patients with acute respiratory distress syndrome (ARDS) undergoing open lung biopsy. Diffuse alveolar damage (DAD), the histological hallmark of ARDS, was present in only 56.4 % of cases. The presence of DAD was associated with higher mortality. Evidence from this and other studies indicates that the clinical criteria for the diagnosis of ARDS identify DAD in only about half of the cases. On the contrary, there is evidence that the clinical course and outcome of ARDS differs in patients with DAD and in patients without DAD. The discovery of biomarkers for the physiological (increased alveolocapillary permeability) or histological (DAD) hallmarks of ARDS is thus of paramount importance.
publishDate 2015
dc.date.none.fl_str_mv 2015
2015-01-01
2015
2015-01-01
2016
2016-12-23
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/11268/6125
url http://hdl.handle.net/11268/6125
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Reconocimiento 3.0 España
https://creativecommons.org/licenses/by/3.0/es/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Reconocimiento 3.0 España
https://creativecommons.org/licenses/by/3.0/es/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:ABACUS. Repositorio de Producción Científica
instname:Universidad Europea (UEM)
instname_str Universidad Europea (UEM)
reponame_str ABACUS. Repositorio de Producción Científica
collection ABACUS. Repositorio de Producción Científica
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