Hidradenitis suppurativa in patients with inflammatory bowel disease: a national multicenter study from the GETECCU-ENEIDA Registry

Background: Hidradenitis suppurativa (HS) is a chronic, recurrent skin disease that may be associated with inflammatory bowel disease (IBD). Objectives: This study aimed to describe the features and therapeutic requirements of IBD and HS in patients who present both entities and the risk factors for...

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Detalles Bibliográficos
Autores: Madero Velázquez, Lucía, Francisco, Ruth de, Herreros, Belén, Yagüe, Carmen, Bujanda, Luis, Calvet, Xavier, Ponferrada, Ángel, Aguas, Mariam, Rodríguez Moranta, Francisco, Marín Jiménez, Ignacio, Catalá, Lourdes, Gargallo Pueyo, Carla, Huguet, José, Mesonero, Francisco, Monfort, David, Sierra Ausín, Mónica, Igualada, Laura, Ricart Gómez, Elena, González Vivó, María, García García, María José, Hernandez Camba, Alejandro, Elorza, Ainara, Zabalza San Martín, Lucía, Ramos, Laura, Martín Arranz, María Dolores, Ruiz Núñez, Isabel, Martínez Montiel, Pilar, Soto, Pilar, Roig, Cristina, Molina, María, Mañosa, Miriam, Alba, Cristina, Barreiro de Acosta, Manuel, Gisbert, Javier P., Ramírez de la Piscina, Patricia, Lorente, Rufo, Zabana, Yamile, Botella, Belen, Riestra, Sabino, Belen Galipienso, Olivia, Busquets, David, Argüelles, Federico, Pascual, José Carlos, Zapater, Pedro, Domènech, Eugeni, Gutiérrez, Ana
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2026
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:dnet:recercat____::9687ee675bd33a95461eb9847864809e
Acceso en línea:https://hdl.handle.net/2445/229241
Access Level:acceso abierto
Palabra clave:Malalties inflamatòries intestinals
Immunologia
Inflammatory bowel diseases
Immunology
Descripción
Sumario:Background: Hidradenitis suppurativa (HS) is a chronic, recurrent skin disease that may be associated with inflammatory bowel disease (IBD). Objectives: This study aimed to describe the features and therapeutic requirements of IBD and HS in patients who present both entities and the risk factors for HS development in patients with IBD. Methods: Case-controlled, retrospective study of all patients diagnosed with IBD-HS in the ENEIDA registry. Cases were paired 1:2 with controls (IBD without HS). Design: This was a retrospective, case-control study. Results: A total of 819 patients were included: 273 patients with IBD-HS and 546 controls. Female sex (62% vs 44%, p = 0.0001), active smoking (45% vs 18%, p = 0.0001), Crohn's disease (CD; 83% vs 55%, p = 0.0001), perianal disease (59% vs 33%, p = 0.0001), extraintestinal manifestations (38% vs 17%, p = 0.0001), and psychiatric disorders (18% vs 2%, p < 0.05) were more frequent among patients with IBD-HS than in controls. The average body mass index was greater in the IBD-HS group. The most frequently HS-affected locations were axillary (57%) and genital (43%) areas. Use of biologicals and CD-related perianal surgery was more common among patients with CD-HS (77% vs 66%, p = 0.003; 37% vs 13%, p < 0.001), compared to controls with only CD. Conclusion: Patients with IBD-HS exhibit a distinctive phenotype with higher therapeutic requirements for the subset of patients with CD-HS compared to those without HS. Assessment of this comorbidity should be considered in patients with suggestive skin lesions and IBD to improve the outcomes of both conditions.

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