Genomic Signatures of Island Colonisation in Highly Diverse Primates
Understanding how small populations cope with loss of genetic diversity and deleterious variation is crucial to address the current biodiversity crisis. Insular populations are particularly interesting as they have often persisted at lower population sizes and higher inbreeding than their mainland c...
| Autores: | , , , , , , , , , , , , |
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| Tipo de recurso: | artículo |
| Fecha de publicación: | 2025 |
| País: | España |
| Institución: | Universitat Autònoma de Barcelona |
| Repositorio: | Dipòsit Digital de Documents de la UAB |
| Idioma: | inglés |
| OAI Identifier: | oai:ddd.uab.cat:317803 |
| Acceso en línea: | https://ddd.uab.cat/record/317803 https://dx.doi.org/urn:doi:10.1111/mec.17815 |
| Access Level: | acceso abierto |
| Palabra clave: | Cercopithecini Conservation genomics Genetic load Guinea- Bissau Intraspecific variation |
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Genomic Signatures of Island Colonisation in Highly Diverse PrimatesColmonero Costeira, Ivo|||0000-0001-9914-0713Guschanski, Katerina|||0000-0002-8493-5457Djaló, S. L.Fernandes, NairCamará, TomásFarh, Kyle Kai-How|||0000-0001-6947-8537Kuderna, Lukas F. K.|||0000-0002-9992-9295Rogers, Jeffrey|||0000-0002-7374-6490Marquès i Bonet, Tomàs|||0000-0002-5597-3075Bruford, M. W.Russo, Isa-Rita|||0000-0001-9504-3633Jensen, Axel|||0000-0003-1766-560XFerreira da Silva, M. J.|||0000-0001-6747-9827CercopitheciniConservation genomicsGenetic loadGuinea- BissauIntraspecific variationUnderstanding how small populations cope with loss of genetic diversity and deleterious variation is crucial to address the current biodiversity crisis. Insular populations are particularly interesting as they have often persisted at lower population sizes and higher inbreeding than their mainland counterparts. While the genome-wide consequences of inbreeding in threatened insular species have received some attention, comparative genomics between insular and mainland populations of widespread and genetically diverse species have rarely been performed. Yet, they are particularly well suited to inform about the consequences of drastic population declines from initially large populations-a phenomenon that is becoming increasingly common. The spot-nosed monkey (Cercopithecus petaurista), the Campbell's monkey (Cercopithecus campbelli) and the green monkey (Chlorocebus sabaeus) are common and genetically diverse West African primates. Insular populations can be found at the Bijagós Archipelago, Guinea-Bissau. Here, we assessed the genome-wide diversity, inbreeding, genetic load and adaptive variation using whole genome sequencing data from insular and mainland populations. In the three species, island populations showed lower genome-wide diversity and higher inbreeding. Genetic drift has likely promoted the conversion of masked genetic load into realised load without increased purging of deleterious variation. Additionally, we found no evidence for accumulation of deleterious variation, suggesting that these populations are not yet at risk of extinction by genetic factors and may act as reservoirs of extant mainland genetic diversity. We highlight, however, that other anthropogenic factors are threatening these insular primates, and therefore conservation management should target their immediate threats and safeguard against additional loss of diversity. 22025-01-0120252025-01-01Articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://ddd.uab.cat/record/317803https://dx.doi.org/urn:doi:10.1111/mec.17815reponame:Dipòsit Digital de Documents de la UABinstname:Universitat Autònoma de BarcelonaInglésengopen accesshttp://purl.org/coar/access_right/c_abf2Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.https://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:ddd.uab.cat:3178032026-06-06T12:50:31Z |
| dc.title.none.fl_str_mv |
Genomic Signatures of Island Colonisation in Highly Diverse Primates |
| title |
Genomic Signatures of Island Colonisation in Highly Diverse Primates |
| spellingShingle |
Genomic Signatures of Island Colonisation in Highly Diverse Primates Colmonero Costeira, Ivo|||0000-0001-9914-0713 Cercopithecini Conservation genomics Genetic load Guinea- Bissau Intraspecific variation |
| title_short |
Genomic Signatures of Island Colonisation in Highly Diverse Primates |
| title_full |
Genomic Signatures of Island Colonisation in Highly Diverse Primates |
| title_fullStr |
Genomic Signatures of Island Colonisation in Highly Diverse Primates |
| title_full_unstemmed |
Genomic Signatures of Island Colonisation in Highly Diverse Primates |
| title_sort |
Genomic Signatures of Island Colonisation in Highly Diverse Primates |
| dc.creator.none.fl_str_mv |
Colmonero Costeira, Ivo|||0000-0001-9914-0713 Guschanski, Katerina|||0000-0002-8493-5457 Djaló, S. L. Fernandes, Nair Camará, Tomás Farh, Kyle Kai-How|||0000-0001-6947-8537 Kuderna, Lukas F. K.|||0000-0002-9992-9295 Rogers, Jeffrey|||0000-0002-7374-6490 Marquès i Bonet, Tomàs|||0000-0002-5597-3075 Bruford, M. W. Russo, Isa-Rita|||0000-0001-9504-3633 Jensen, Axel|||0000-0003-1766-560X Ferreira da Silva, M. J.|||0000-0001-6747-9827 |
| author |
Colmonero Costeira, Ivo|||0000-0001-9914-0713 |
| author_facet |
Colmonero Costeira, Ivo|||0000-0001-9914-0713 Guschanski, Katerina|||0000-0002-8493-5457 Djaló, S. L. Fernandes, Nair Camará, Tomás Farh, Kyle Kai-How|||0000-0001-6947-8537 Kuderna, Lukas F. K.|||0000-0002-9992-9295 Rogers, Jeffrey|||0000-0002-7374-6490 Marquès i Bonet, Tomàs|||0000-0002-5597-3075 Bruford, M. W. Russo, Isa-Rita|||0000-0001-9504-3633 Jensen, Axel|||0000-0003-1766-560X Ferreira da Silva, M. J.|||0000-0001-6747-9827 |
| author_role |
author |
| author2 |
Guschanski, Katerina|||0000-0002-8493-5457 Djaló, S. L. Fernandes, Nair Camará, Tomás Farh, Kyle Kai-How|||0000-0001-6947-8537 Kuderna, Lukas F. K.|||0000-0002-9992-9295 Rogers, Jeffrey|||0000-0002-7374-6490 Marquès i Bonet, Tomàs|||0000-0002-5597-3075 Bruford, M. W. Russo, Isa-Rita|||0000-0001-9504-3633 Jensen, Axel|||0000-0003-1766-560X Ferreira da Silva, M. J.|||0000-0001-6747-9827 |
| author2_role |
author author author author author author author author author author author author |
| dc.subject.none.fl_str_mv |
Cercopithecini Conservation genomics Genetic load Guinea- Bissau Intraspecific variation |
| topic |
Cercopithecini Conservation genomics Genetic load Guinea- Bissau Intraspecific variation |
| description |
Understanding how small populations cope with loss of genetic diversity and deleterious variation is crucial to address the current biodiversity crisis. Insular populations are particularly interesting as they have often persisted at lower population sizes and higher inbreeding than their mainland counterparts. While the genome-wide consequences of inbreeding in threatened insular species have received some attention, comparative genomics between insular and mainland populations of widespread and genetically diverse species have rarely been performed. Yet, they are particularly well suited to inform about the consequences of drastic population declines from initially large populations-a phenomenon that is becoming increasingly common. The spot-nosed monkey (Cercopithecus petaurista), the Campbell's monkey (Cercopithecus campbelli) and the green monkey (Chlorocebus sabaeus) are common and genetically diverse West African primates. Insular populations can be found at the Bijagós Archipelago, Guinea-Bissau. Here, we assessed the genome-wide diversity, inbreeding, genetic load and adaptive variation using whole genome sequencing data from insular and mainland populations. In the three species, island populations showed lower genome-wide diversity and higher inbreeding. Genetic drift has likely promoted the conversion of masked genetic load into realised load without increased purging of deleterious variation. Additionally, we found no evidence for accumulation of deleterious variation, suggesting that these populations are not yet at risk of extinction by genetic factors and may act as reservoirs of extant mainland genetic diversity. We highlight, however, that other anthropogenic factors are threatening these insular primates, and therefore conservation management should target their immediate threats and safeguard against additional loss of diversity. |
| publishDate |
2025 |
| dc.date.none.fl_str_mv |
2 2025-01-01 2025 2025-01-01 |
| dc.type.none.fl_str_mv |
Article http://purl.org/coar/resource_type/c_6501 VoR http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| dc.type.openaire.fl_str_mv |
info:eu-repo/semantics/article |
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article |
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https://ddd.uab.cat/record/317803 https://dx.doi.org/urn:doi:10.1111/mec.17815 |
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https://ddd.uab.cat/record/317803 https://dx.doi.org/urn:doi:10.1111/mec.17815 |
| dc.language.none.fl_str_mv |
Inglés eng |
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Inglés |
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eng |
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open access http://purl.org/coar/access_right/c_abf2 https://creativecommons.org/licenses/by/4.0/ |
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info:eu-repo/semantics/openAccess |
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open access http://purl.org/coar/access_right/c_abf2 https://creativecommons.org/licenses/by/4.0/ |
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openAccess |
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