Corticosteroid Injection for the Treatment of Morton's Neuroma: a Prospective, Double-Blinded, Randomized, Placebo-Controlled Trial

BACKGROUND: The effectiveness of corticosteroid injection for the treatment of Morton's neuroma is unclear. In addition, most of the studies related to it are case-control or retrospective case series. The purpose of this study was to compare the effectiveness between corticosteroid injecti...

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Detalles Bibliográficos
Autores: Lizano Díez, Javier, Ginés-Cespedosa, Alberto, Alentorn Geli, Eduard, Pérez-Prieto, Daniel, González-Lucena, Gemma, Gamba, Carlo, de Zabala, Santiago, Solano-López, Alberto, Rigol-Ramón, Pau
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2017
País:España
Institución:Universitat Pompeu Fabra
Repositorio:Repositorio Digital de la UPF
OAI Identifier:oai:repositori.upf.edu:10230/34714
Acceso en línea:http://hdl.handle.net/10230/34714
http://dx.doi.org/10.1177/1071100717709569
Access Level:acceso abierto
Palabra clave:Anestèsia
Neurinoma
Morton’s neuroma
Corticosteroid
Injection
Local anesthetic
Descripción
Sumario:BACKGROUND: The effectiveness of corticosteroid injection for the treatment of Morton's neuroma is unclear. In addition, most of the studies related to it are case-control or retrospective case series. The purpose of this study was to compare the effectiveness between corticosteroid injection associated with local anesthetic and local anesthetic alone (placebo control group) for the treatment of Morton's neuroma. METHODS: Forty-one patients with a diagnosis of Morton's neuroma were randomized to receive 3 injections of either a corticosteroid plus a local anesthetic or a local anesthetic alone. The patients and the researcher who collected data were blinded to the treatment groups. The visual analog scale for pain and the American Orthopaedic Foot & Ankle Score (metatarsophalangeal/interphalangeal score) were obtained at baseline, after each injection, and at 3 and 6 months after the last injection. RESULTS: There were no significant between-group differences in terms of pain and function improvement at 3 and 6 months after treatment completion in comparison with baseline values. At the end of the study, 17 (48.5%) patients requested surgical excision of the neuroma: 7 (44%) in the experimental group and 10 (53%) in the control group ( P = 1.0). CONCLUSION: The injection of a corticosteroid plus a local anesthetic was not superior to a local anesthetic alone in terms of pain and function improvement in patients with Morton's neuroma.