The global burden attributable to low bone mineral density
Introduction: The Global Burden of Disease Study 2010 estimated the worldwide health burden of 291 diseases and injuries and 67 risk factors by calculating disability-adjusted life years (DALYs). Osteoporosis was not considered as a disease, and bone mineral density (BMD) was analysed as a risk fact...
| Autores: | , , , , , , , , , , , , , , , , |
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| Formato: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2014 |
| País: | España |
| Recursos: | Universidad de Barcelona |
| Repositorio: | Dipòsit Digital de la UB |
| OAI Identifier: | oai:diposit.ub.edu:2445/112522 |
| Acesso em linha: | https://hdl.handle.net/2445/112522 |
| Access Level: | acceso abierto |
| Palavra-chave: | Osteoporosi Malalties dels ossos Densitometria òssia Salut pública Fractures Ressenyes sistemàtiques (Investigació mèdica) Osteoporosis Bone diseases Bone densitometry Public health Systematic reviews (Medical research) |
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The global burden attributable to low bone mineral densitySànchez Riera, LídiaCarnahan, E.Vos, TheoVeerman, L.Norman, R.Lim, S. S.Hoy, D.Smith, E.Wilson, N.Nolla Solé, Joan MiquelChen, J. S.Macara, M.Kamalaraj, N.Li, Y.Kok, C.Santos-Hernández, C.March, LynOsteoporosiMalalties dels ossosDensitometria òssiaSalut públicaFracturesRessenyes sistemàtiques (Investigació mèdica)OsteoporosisBone diseasesBone densitometryPublic healthFracturesSystematic reviews (Medical research)Introduction: The Global Burden of Disease Study 2010 estimated the worldwide health burden of 291 diseases and injuries and 67 risk factors by calculating disability-adjusted life years (DALYs). Osteoporosis was not considered as a disease, and bone mineral density (BMD) was analysed as a risk factor for fractures, which formed part of the health burden due to falls. Objectives: To calculate (1) the global distribution of BMD, (2) its population attributable fraction (PAF) for fractures and subsequently for falls, and (3) the number of DALYs due to BMD. Methods: A systematic review was performed seeking population-based studies in which BMD was measured by dual-energy X-ray absorptiometry at the femoral neck in people aged 50 years and over. Age- and sex-specific mean ± SD BMD values (g/cm2) were extracted from eligible studies. Comparative risk assessment methodology was used to calculate PAFs of BMD for fractures. The theoretical minimum risk exposure distribution was estimated as the age- and sex-specific 90th centile from the Third National Health and Nutrition Examination Survey (NHANES III). Relative risks of fractures were obtained from a previous meta-analysis. Hospital data were used to calculate the fraction of the health burden of falls that was due to fractures. Results: Global deaths and DALYs attributable to low BMD increased from 103 000 and 3 125 000 in 1990 to 188 000 and 5 216 000 in 2010, respectively. The percentage of low BMD in the total global burden almost doubled from 1990 (0.12%) to 2010 (0.21%). Around one-third of falls-related deaths were attributable to low BMD. Conclusions: Low BMD is responsible for a growing global health burden, only partially representative of the real burden of osteoporosis.BMJ Publishing Group2014info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://hdl.handle.net/2445/112522Articles publicats en revistes (Ciències Clíniques)reponame:Dipòsit Digital de la UBinstname:Universidad de BarcelonaInglésReproducció del document publicat a: https://doi.org/10.1136/annrheumdis-2013-204320Annals of the Rheumatic Diseases, 2014, vol. 73, num. 9, p. 1635-1645https://doi.org/10.1136/annrheumdis-2013-204320(c) BMJ Publishing Group, 2014info:eu-repo/semantics/openAccessoai:diposit.ub.edu:2445/1125222026-05-27T06:46:51Z |
| dc.title.none.fl_str_mv |
The global burden attributable to low bone mineral density |
| title |
The global burden attributable to low bone mineral density |
| spellingShingle |
The global burden attributable to low bone mineral density Sànchez Riera, Lídia Osteoporosi Malalties dels ossos Densitometria òssia Salut pública Fractures Ressenyes sistemàtiques (Investigació mèdica) Osteoporosis Bone diseases Bone densitometry Public health Fractures Systematic reviews (Medical research) |
| title_short |
The global burden attributable to low bone mineral density |
| title_full |
The global burden attributable to low bone mineral density |
| title_fullStr |
The global burden attributable to low bone mineral density |
| title_full_unstemmed |
The global burden attributable to low bone mineral density |
| title_sort |
The global burden attributable to low bone mineral density |
| dc.creator.none.fl_str_mv |
Sànchez Riera, Lídia Carnahan, E. Vos, Theo Veerman, L. Norman, R. Lim, S. S. Hoy, D. Smith, E. Wilson, N. Nolla Solé, Joan Miquel Chen, J. S. Macara, M. Kamalaraj, N. Li, Y. Kok, C. Santos-Hernández, C. March, Lyn |
| author |
Sànchez Riera, Lídia |
| author_facet |
Sànchez Riera, Lídia Carnahan, E. Vos, Theo Veerman, L. Norman, R. Lim, S. S. Hoy, D. Smith, E. Wilson, N. Nolla Solé, Joan Miquel Chen, J. S. Macara, M. Kamalaraj, N. Li, Y. Kok, C. Santos-Hernández, C. March, Lyn |
| author_role |
author |
| author2 |
Carnahan, E. Vos, Theo Veerman, L. Norman, R. Lim, S. S. Hoy, D. Smith, E. Wilson, N. Nolla Solé, Joan Miquel Chen, J. S. Macara, M. Kamalaraj, N. Li, Y. Kok, C. Santos-Hernández, C. March, Lyn |
| author2_role |
author author author author author author author author author author author author author author author author |
| dc.subject.none.fl_str_mv |
Osteoporosi Malalties dels ossos Densitometria òssia Salut pública Fractures Ressenyes sistemàtiques (Investigació mèdica) Osteoporosis Bone diseases Bone densitometry Public health Fractures Systematic reviews (Medical research) |
| topic |
Osteoporosi Malalties dels ossos Densitometria òssia Salut pública Fractures Ressenyes sistemàtiques (Investigació mèdica) Osteoporosis Bone diseases Bone densitometry Public health Fractures Systematic reviews (Medical research) |
| description |
Introduction: The Global Burden of Disease Study 2010 estimated the worldwide health burden of 291 diseases and injuries and 67 risk factors by calculating disability-adjusted life years (DALYs). Osteoporosis was not considered as a disease, and bone mineral density (BMD) was analysed as a risk factor for fractures, which formed part of the health burden due to falls. Objectives: To calculate (1) the global distribution of BMD, (2) its population attributable fraction (PAF) for fractures and subsequently for falls, and (3) the number of DALYs due to BMD. Methods: A systematic review was performed seeking population-based studies in which BMD was measured by dual-energy X-ray absorptiometry at the femoral neck in people aged 50 years and over. Age- and sex-specific mean ± SD BMD values (g/cm2) were extracted from eligible studies. Comparative risk assessment methodology was used to calculate PAFs of BMD for fractures. The theoretical minimum risk exposure distribution was estimated as the age- and sex-specific 90th centile from the Third National Health and Nutrition Examination Survey (NHANES III). Relative risks of fractures were obtained from a previous meta-analysis. Hospital data were used to calculate the fraction of the health burden of falls that was due to fractures. Results: Global deaths and DALYs attributable to low BMD increased from 103 000 and 3 125 000 in 1990 to 188 000 and 5 216 000 in 2010, respectively. The percentage of low BMD in the total global burden almost doubled from 1990 (0.12%) to 2010 (0.21%). Around one-third of falls-related deaths were attributable to low BMD. Conclusions: Low BMD is responsible for a growing global health burden, only partially representative of the real burden of osteoporosis. |
| publishDate |
2014 |
| dc.date.none.fl_str_mv |
2014 |
| dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
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article |
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publishedVersion |
| dc.identifier.none.fl_str_mv |
https://hdl.handle.net/2445/112522 |
| url |
https://hdl.handle.net/2445/112522 |
| dc.language.none.fl_str_mv |
Inglés |
| language_invalid_str_mv |
Inglés |
| dc.relation.none.fl_str_mv |
Reproducció del document publicat a: https://doi.org/10.1136/annrheumdis-2013-204320 Annals of the Rheumatic Diseases, 2014, vol. 73, num. 9, p. 1635-1645 https://doi.org/10.1136/annrheumdis-2013-204320 |
| dc.rights.none.fl_str_mv |
(c) BMJ Publishing Group, 2014 info:eu-repo/semantics/openAccess |
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(c) BMJ Publishing Group, 2014 |
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openAccess |
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application/pdf |
| dc.publisher.none.fl_str_mv |
BMJ Publishing Group |
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BMJ Publishing Group |
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Articles publicats en revistes (Ciències Clíniques) reponame:Dipòsit Digital de la UB instname:Universidad de Barcelona |
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Universidad de Barcelona |
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Dipòsit Digital de la UB |
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Dipòsit Digital de la UB |
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