Intense Pulsed Light Therapy for Dry Eye Disease: Analyzing Temporal Changes in Tear Film Stability and Ocular Surface between IPL Sessions

Background: Dry eye disease (DED), a prevalent condition with a multifactorial etiology, significantly impacts global health by causing discomfort and visual disturbance. This historical cohort study evaluates the efficacy of Intense Pulsed Light (IPL) therapy on meibomian gland dysfunction (MGD)-re...

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Authors: Pac, Cristina Patricia, Sánchez González, José María, Rocha de Lossada, Carlos, Mercea, Nadina, Ferrari, Francis, Preda, Maria Alexandra, Rosca, Cosmin, Munteanu, Mihnea
Format: article
Status:Published version
Publication Date:2024
Country:España
Institution:Universidad de Sevilla (US)
Repository:idUS. Depósito de Investigación de la Universidad de Sevilla
OAI Identifier:oai:idus.us.es:11441/161456
Online Access:https://hdl.handle.net/11441/161456
https://doi.org/10.3390/healthcare12111119
Access Level:Open access
Keyword:dry eye disease
intense pulsed light
meibomian gland dysfunction
ocular surface health
evaporative dry eye
tear film stability
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spelling Intense Pulsed Light Therapy for Dry Eye Disease: Analyzing Temporal Changes in Tear Film Stability and Ocular Surface between IPL SessionsPac, Cristina PatriciaSánchez González, José MaríaRocha de Lossada, CarlosMercea, NadinaFerrari, FrancisPreda, Maria AlexandraRosca, CosminMunteanu, Mihneadry eye diseaseintense pulsed lightmeibomian gland dysfunctionocular surface healthevaporative dry eyetear film stabilityBackground: Dry eye disease (DED), a prevalent condition with a multifactorial etiology, significantly impacts global health by causing discomfort and visual disturbance. This historical cohort study evaluates the efficacy of Intense Pulsed Light (IPL) therapy on meibomian gland dysfunction (MGD)-related evaporative DED. Methods: The study involved 110 patients (220 eyes) who underwent IPL therapy. Ethical approval was secured, and informed consent was obtained from all participants. A Tearcheck® (ESWvision, Houdan, France) device was used for ocular surface evaluation, measuring tear film stability (NIFBUT, NIABUT), tear film quantity (CTMH, TTMH), and inflammation (OSIE). The study assessed tear film and ocular surface health across multiple IPL sessions. Results: Significant improvements were observed in subjective symptoms (EFT score increased from 29.10 ± 8.87 to 35.91 ± 7.03, p < 0.01), tear film stability (NIFBUT increased from 9.37 ± 6.04 to 10.78 ± 5.83 s, p < 0.01; NIABUT increased from 11.07 ± 4.98 to 12.34 ± 4.66 s, p < 0.01), and tear film surface evaluation (TFSE score decreased from 337.78 ± 414.08 to 206.02 ± 240.44, p < 0.01). Tear film quantity remained unchanged (CTMH and TTMH, p > 0.05). Conclusions: IPL therapy is a promising treatment for DED, improving symptoms and ocular surface health. Further research is warranted to explore long-term efficacy and optimization.MDPIFísica de la Materia CondensadaCirugía2024info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttps://hdl.handle.net/11441/161456https://doi.org/10.3390/healthcare12111119reponame:idUS. Depósito de Investigación de la Universidad de Sevillainstname:Universidad de Sevilla (US)InglésHealthcare, 12 (11), 1119.https://doi.org/10.3390/healthcare12111119info:eu-repo/semantics/openAccessoai:idus.us.es:11441/1614562026-06-17T12:51:07Z
dc.title.none.fl_str_mv Intense Pulsed Light Therapy for Dry Eye Disease: Analyzing Temporal Changes in Tear Film Stability and Ocular Surface between IPL Sessions
title Intense Pulsed Light Therapy for Dry Eye Disease: Analyzing Temporal Changes in Tear Film Stability and Ocular Surface between IPL Sessions
spellingShingle Intense Pulsed Light Therapy for Dry Eye Disease: Analyzing Temporal Changes in Tear Film Stability and Ocular Surface between IPL Sessions
Pac, Cristina Patricia
dry eye disease
intense pulsed light
meibomian gland dysfunction
ocular surface health
evaporative dry eye
tear film stability
title_short Intense Pulsed Light Therapy for Dry Eye Disease: Analyzing Temporal Changes in Tear Film Stability and Ocular Surface between IPL Sessions
title_full Intense Pulsed Light Therapy for Dry Eye Disease: Analyzing Temporal Changes in Tear Film Stability and Ocular Surface between IPL Sessions
title_fullStr Intense Pulsed Light Therapy for Dry Eye Disease: Analyzing Temporal Changes in Tear Film Stability and Ocular Surface between IPL Sessions
title_full_unstemmed Intense Pulsed Light Therapy for Dry Eye Disease: Analyzing Temporal Changes in Tear Film Stability and Ocular Surface between IPL Sessions
title_sort Intense Pulsed Light Therapy for Dry Eye Disease: Analyzing Temporal Changes in Tear Film Stability and Ocular Surface between IPL Sessions
dc.creator.none.fl_str_mv Pac, Cristina Patricia
Sánchez González, José María
Rocha de Lossada, Carlos
Mercea, Nadina
Ferrari, Francis
Preda, Maria Alexandra
Rosca, Cosmin
Munteanu, Mihnea
author Pac, Cristina Patricia
author_facet Pac, Cristina Patricia
Sánchez González, José María
Rocha de Lossada, Carlos
Mercea, Nadina
Ferrari, Francis
Preda, Maria Alexandra
Rosca, Cosmin
Munteanu, Mihnea
author_role author
author2 Sánchez González, José María
Rocha de Lossada, Carlos
Mercea, Nadina
Ferrari, Francis
Preda, Maria Alexandra
Rosca, Cosmin
Munteanu, Mihnea
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Física de la Materia Condensada
Cirugía
dc.subject.none.fl_str_mv dry eye disease
intense pulsed light
meibomian gland dysfunction
ocular surface health
evaporative dry eye
tear film stability
topic dry eye disease
intense pulsed light
meibomian gland dysfunction
ocular surface health
evaporative dry eye
tear film stability
description Background: Dry eye disease (DED), a prevalent condition with a multifactorial etiology, significantly impacts global health by causing discomfort and visual disturbance. This historical cohort study evaluates the efficacy of Intense Pulsed Light (IPL) therapy on meibomian gland dysfunction (MGD)-related evaporative DED. Methods: The study involved 110 patients (220 eyes) who underwent IPL therapy. Ethical approval was secured, and informed consent was obtained from all participants. A Tearcheck® (ESWvision, Houdan, France) device was used for ocular surface evaluation, measuring tear film stability (NIFBUT, NIABUT), tear film quantity (CTMH, TTMH), and inflammation (OSIE). The study assessed tear film and ocular surface health across multiple IPL sessions. Results: Significant improvements were observed in subjective symptoms (EFT score increased from 29.10 ± 8.87 to 35.91 ± 7.03, p < 0.01), tear film stability (NIFBUT increased from 9.37 ± 6.04 to 10.78 ± 5.83 s, p < 0.01; NIABUT increased from 11.07 ± 4.98 to 12.34 ± 4.66 s, p < 0.01), and tear film surface evaluation (TFSE score decreased from 337.78 ± 414.08 to 206.02 ± 240.44, p < 0.01). Tear film quantity remained unchanged (CTMH and TTMH, p > 0.05). Conclusions: IPL therapy is a promising treatment for DED, improving symptoms and ocular surface health. Further research is warranted to explore long-term efficacy and optimization.
publishDate 2024
dc.date.none.fl_str_mv 2024
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/11441/161456
https://doi.org/10.3390/healthcare12111119
url https://hdl.handle.net/11441/161456
https://doi.org/10.3390/healthcare12111119
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Healthcare, 12 (11), 1119.
https://doi.org/10.3390/healthcare12111119
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:idUS. Depósito de Investigación de la Universidad de Sevilla
instname:Universidad de Sevilla (US)
instname_str Universidad de Sevilla (US)
reponame_str idUS. Depósito de Investigación de la Universidad de Sevilla
collection idUS. Depósito de Investigación de la Universidad de Sevilla
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15.812429

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