Lactational responses of heat-stressed dairy goats to dietary L-carnitine supplementation

Heat stress causes significant losses in milk production, and nutritional strategies are needed to alleviate its effects. Endogenous carnitine synthesis is also reduced by heat stress (HS). Carnitine plays a central role in fatty acid oxidation and buffers the toxic effects of acyl groups. We hypoth...

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Autores: Mehaba, Nabil|||0000-0002-1701-5407, Salama, Ahmed A. K.|||0000-0003-2065-9702, Such i Martí, Francesc Xavier|||0000-0002-9712-4477, Albanell Trullas, Elena|||0000-0002-6158-7736, Caja López, Gerardo|||0000-0001-8606-3587
Tipo de recurso: artículo
Fecha de publicación:2019
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:216629
Acceso en línea:https://ddd.uab.cat/record/216629
https://dx.doi.org/urn:doi:10.3390/ani9080567
Access Level:acceso abierto
Palabra clave:L-carnitine
Heat stress
Feed sorting
Metabolism
Dairy goats
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spelling Lactational responses of heat-stressed dairy goats to dietary L-carnitine supplementationMehaba, Nabil|||0000-0002-1701-5407Salama, Ahmed A. K.|||0000-0003-2065-9702Such i Martí, Francesc Xavier|||0000-0002-9712-4477Albanell Trullas, Elena|||0000-0002-6158-7736Caja López, Gerardo|||0000-0001-8606-3587L-carnitineHeat stressFeed sortingMetabolismDairy goatsHeat stress causes significant losses in milk production, and nutritional strategies are needed to alleviate its effects. Endogenous carnitine synthesis is also reduced by heat stress (HS). Carnitine plays a central role in fatty acid oxidation and buffers the toxic effects of acyl groups. We hypothesized that carnitine supplementation would make up for any carnitine deficiencies during HS and improve lipid metabolism. The objective was to evaluate rumen-protected L-carnitine (CAR) supplementation in dairy goats under thermo-neutral (TN) or HS conditions. Four Murciano-Granadina dairy goats were used in a four × four Latin square design. Goats were allocated to one of four treatments in a two × two factorial arrangement. Factors were 1) diet: control (CON) or supplementation with CAR (1 g/d); and 2) ambient conditions: TN (15 to 20 °C) or HS (0900 to 2100 h at 35 °C, 2100 to 0900 h at 28 °C). Blood free-, acetyl-, and total-carnitine concentrations increased almost three times by supplementation. Despite this efficient absorption, CAR had no effect on feed intake, milk production or blood metabolites in TN or HS conditions. Heat stress increased rectal temperature and respiratory rate. Additionally, HS goats experienced 26% loss in feed intake, but they tended to eat longer particle sizes. Compared to TN, heat-stressed goats lost more subcutaneous fat (difference in fat thickness measured before and after each period = -0.72 vs. +0.64 mm). In conclusion, supplemented L-carnitine was efficiently absorbed, but it had no lactational effects on performance of goats under thermo-neutral or heat stress conditions. 22019-01-0120192019-01-01Articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://ddd.uab.cat/record/216629https://dx.doi.org/urn:doi:10.3390/ani9080567reponame:Dipòsit Digital de Documents de la UABinstname:Universitat Autònoma de BarcelonaInglésengMinisterio de Economía y Competitividad https://doi.org/10.13039/501100003329 AGL2013-44061-Ropen accesshttp://purl.org/coar/access_right/c_abf2Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.https://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:ddd.uab.cat:2166292026-06-06T12:50:31Z
dc.title.none.fl_str_mv Lactational responses of heat-stressed dairy goats to dietary L-carnitine supplementation
title Lactational responses of heat-stressed dairy goats to dietary L-carnitine supplementation
spellingShingle Lactational responses of heat-stressed dairy goats to dietary L-carnitine supplementation
Mehaba, Nabil|||0000-0002-1701-5407
L-carnitine
Heat stress
Feed sorting
Metabolism
Dairy goats
title_short Lactational responses of heat-stressed dairy goats to dietary L-carnitine supplementation
title_full Lactational responses of heat-stressed dairy goats to dietary L-carnitine supplementation
title_fullStr Lactational responses of heat-stressed dairy goats to dietary L-carnitine supplementation
title_full_unstemmed Lactational responses of heat-stressed dairy goats to dietary L-carnitine supplementation
title_sort Lactational responses of heat-stressed dairy goats to dietary L-carnitine supplementation
dc.creator.none.fl_str_mv Mehaba, Nabil|||0000-0002-1701-5407
Salama, Ahmed A. K.|||0000-0003-2065-9702
Such i Martí, Francesc Xavier|||0000-0002-9712-4477
Albanell Trullas, Elena|||0000-0002-6158-7736
Caja López, Gerardo|||0000-0001-8606-3587
author Mehaba, Nabil|||0000-0002-1701-5407
author_facet Mehaba, Nabil|||0000-0002-1701-5407
Salama, Ahmed A. K.|||0000-0003-2065-9702
Such i Martí, Francesc Xavier|||0000-0002-9712-4477
Albanell Trullas, Elena|||0000-0002-6158-7736
Caja López, Gerardo|||0000-0001-8606-3587
author_role author
author2 Salama, Ahmed A. K.|||0000-0003-2065-9702
Such i Martí, Francesc Xavier|||0000-0002-9712-4477
Albanell Trullas, Elena|||0000-0002-6158-7736
Caja López, Gerardo|||0000-0001-8606-3587
author2_role author
author
author
author
dc.subject.none.fl_str_mv L-carnitine
Heat stress
Feed sorting
Metabolism
Dairy goats
topic L-carnitine
Heat stress
Feed sorting
Metabolism
Dairy goats
description Heat stress causes significant losses in milk production, and nutritional strategies are needed to alleviate its effects. Endogenous carnitine synthesis is also reduced by heat stress (HS). Carnitine plays a central role in fatty acid oxidation and buffers the toxic effects of acyl groups. We hypothesized that carnitine supplementation would make up for any carnitine deficiencies during HS and improve lipid metabolism. The objective was to evaluate rumen-protected L-carnitine (CAR) supplementation in dairy goats under thermo-neutral (TN) or HS conditions. Four Murciano-Granadina dairy goats were used in a four × four Latin square design. Goats were allocated to one of four treatments in a two × two factorial arrangement. Factors were 1) diet: control (CON) or supplementation with CAR (1 g/d); and 2) ambient conditions: TN (15 to 20 °C) or HS (0900 to 2100 h at 35 °C, 2100 to 0900 h at 28 °C). Blood free-, acetyl-, and total-carnitine concentrations increased almost three times by supplementation. Despite this efficient absorption, CAR had no effect on feed intake, milk production or blood metabolites in TN or HS conditions. Heat stress increased rectal temperature and respiratory rate. Additionally, HS goats experienced 26% loss in feed intake, but they tended to eat longer particle sizes. Compared to TN, heat-stressed goats lost more subcutaneous fat (difference in fat thickness measured before and after each period = -0.72 vs. +0.64 mm). In conclusion, supplemented L-carnitine was efficiently absorbed, but it had no lactational effects on performance of goats under thermo-neutral or heat stress conditions.
publishDate 2019
dc.date.none.fl_str_mv 2
2019-01-01
2019
2019-01-01
dc.type.none.fl_str_mv Article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://ddd.uab.cat/record/216629
https://dx.doi.org/urn:doi:10.3390/ani9080567
url https://ddd.uab.cat/record/216629
https://dx.doi.org/urn:doi:10.3390/ani9080567
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.relation.none.fl_str_mv Ministerio de Economía y Competitividad https://doi.org/10.13039/501100003329 AGL2013-44061-R
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
https://creativecommons.org/licenses/by/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
https://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Dipòsit Digital de Documents de la UAB
instname:Universitat Autònoma de Barcelona
instname_str Universitat Autònoma de Barcelona
reponame_str Dipòsit Digital de Documents de la UAB
collection Dipòsit Digital de Documents de la UAB
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