Protocols for uncontrolled donation after circulatory death: a systematic review of international guidelines, practices and transplant outcomes

15 p.

Detalles Bibliográficos
Autores: Ortega Deballón, Iván María|||0000-0002-0819-2399, Hornby, Laura, Shemie, Sam D.
Tipo de recurso: artículo
Fecha de publicación:2015
País:España
Institución:Universidad de Alcalá (UAH)
Repositorio:e_Buah Biblioteca Digital Universidad de Alcalá
Idioma:inglés
OAI Identifier:oai:ebuah.uah.es:10017/59991
Acceso en línea:http://hdl.handle.net/10017/59991
https://dx.doi.org/10.1186/s13054-015-0985-7
Access Level:acceso abierto
Palabra clave:Uncontrolled donation
Circulatory death
Protocols
Enfermería
Nursery
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spelling Protocols for uncontrolled donation after circulatory death: a systematic review of international guidelines, practices and transplant outcomesOrtega Deballón, Iván María|||0000-0002-0819-2399Hornby, LauraShemie, Sam D.Uncontrolled donationCirculatory deathProtocolsEnfermeríaNursery15 p.Introduction: A chronic shortage of organs remains the main factor limiting organ transplantation. Many countries have explored the option of uncontrolled donation after circulatory death (uDCD) in order to expand the donor pool. Little is known regarding the variability of practices and outcomes between existing protocols. This systematic review addresses this knowledge gap informing policy makers, researchers, and clinicians for future protocol implementation. Methods: We searched MEDLINE, EMBASE, and Google Scholar electronic databases from 2005 to March 2015 as well as the reference lists of selected studies, abstracts, unpublished reports, personal libraries, professional organization reports, and government agency statements on uDCD. We contacted leading authors and organizations to request their protocols and guidelines. Two reviewers extracted main variables. In studies reporting transplant outcomes, we added type, quantity, quality of organs procured, and complications reported. Internal validity and the quality of the studies reporting outcomes were assessed, as were the methodological rigour and transparency in which a guideline was developed. The review was included in the international prospective register of systematic reviews (Prospero, CRD42014015258). Results: Six guidelines and 18 outcome studies were analysed. The six guidelines are based on limited evidence and major differences exist between them at each step of the uDCD process. The outcome studies report good results for kidney, liver, and lung transplantation with high discard rates for livers. Conclusions: Despite procedural, medical, economic, legal, and ethical challenges, the uDCD strategy is a viable option for increasing the organ donation pool. Variations in practice and heterogeneity of outcomes preclude a meta-analysis and prevented the linking of outcomes to specific uDCD protocols. Further standardization of protocols and outcomes is required, as is further research into the role of extracorporeal resuscitation and other novel therapies for treatment of some refractory cardiac arrest. It is essential to ensure the maintenance of trust in uDCD programs by health professionals and the public.20152015-12-01journal articlehttp://purl.org/coar/resource_type/c_6501NAhttp://purl.org/coar/version/c_be7fb7dd8ff6fe43info:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10017/59991https://dx.doi.org/10.1186/s13054-015-0985-7reponame:e_Buah Biblioteca Digital Universidad de Alcaláinstname:Universidad de Alcalá (UAH)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Attribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:ebuah.uah.es:10017/599912026-06-18T11:13:07Z
dc.title.none.fl_str_mv Protocols for uncontrolled donation after circulatory death: a systematic review of international guidelines, practices and transplant outcomes
title Protocols for uncontrolled donation after circulatory death: a systematic review of international guidelines, practices and transplant outcomes
spellingShingle Protocols for uncontrolled donation after circulatory death: a systematic review of international guidelines, practices and transplant outcomes
Ortega Deballón, Iván María|||0000-0002-0819-2399
Uncontrolled donation
Circulatory death
Protocols
Enfermería
Nursery
title_short Protocols for uncontrolled donation after circulatory death: a systematic review of international guidelines, practices and transplant outcomes
title_full Protocols for uncontrolled donation after circulatory death: a systematic review of international guidelines, practices and transplant outcomes
title_fullStr Protocols for uncontrolled donation after circulatory death: a systematic review of international guidelines, practices and transplant outcomes
title_full_unstemmed Protocols for uncontrolled donation after circulatory death: a systematic review of international guidelines, practices and transplant outcomes
title_sort Protocols for uncontrolled donation after circulatory death: a systematic review of international guidelines, practices and transplant outcomes
dc.creator.none.fl_str_mv Ortega Deballón, Iván María|||0000-0002-0819-2399
Hornby, Laura
Shemie, Sam D.
author Ortega Deballón, Iván María|||0000-0002-0819-2399
author_facet Ortega Deballón, Iván María|||0000-0002-0819-2399
Hornby, Laura
Shemie, Sam D.
author_role author
author2 Hornby, Laura
Shemie, Sam D.
author2_role author
author
dc.subject.none.fl_str_mv Uncontrolled donation
Circulatory death
Protocols
Enfermería
Nursery
topic Uncontrolled donation
Circulatory death
Protocols
Enfermería
Nursery
description 15 p.
publishDate 2015
dc.date.none.fl_str_mv 2015
2015-12-01
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
NA
http://purl.org/coar/version/c_be7fb7dd8ff6fe43
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/10017/59991
https://dx.doi.org/10.1186/s13054-015-0985-7
url http://hdl.handle.net/10017/59991
https://dx.doi.org/10.1186/s13054-015-0985-7
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:e_Buah Biblioteca Digital Universidad de Alcalá
instname:Universidad de Alcalá (UAH)
instname_str Universidad de Alcalá (UAH)
reponame_str e_Buah Biblioteca Digital Universidad de Alcalá
collection e_Buah Biblioteca Digital Universidad de Alcalá
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score 15,300724

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