Incidence of mandibular osteoradionecrosis (MORN) after intensity modulated radiotherapy (IMRT) versus 3D conformal radiotherapy (3D-CRT): A systematic review

Background: Analyze the incidence of MORN after head and neck radiotherapy by two novel irradiation techniques. 3DCRT and IMRT and compare the success rates of distinct authors. Material and Methods: An electronic search in Pubmed (MEDLINE), Ovid. Google Scholar and Cochrane Library (Wiley). databas...

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Detalles Bibliográficos
Autores: Céspedes Ajún, Carlos Arturo, Amghar Maach, Sara, Gay Escoda, Cosme
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2022
País:España
Institución:Universidad de Barcelona
Repositorio:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/192291
Acceso en línea:https://hdl.handle.net/2445/192291
Access Level:acceso abierto
Palabra clave:Radioteràpia
Necrosi
Cap
Coll
Radiotherapy
Necrosis
Head
Neck
Descripción
Sumario:Background: Analyze the incidence of MORN after head and neck radiotherapy by two novel irradiation techniques. 3DCRT and IMRT and compare the success rates of distinct authors. Material and Methods: An electronic search in Pubmed (MEDLINE), Ovid. Google Scholar and Cochrane Library (Wiley). databases was conducted with the key words Radiotherapy, Conformal[Mesh] OR Radiotherapy. Intensity-Modulated[Mesh]) AND Osteoradionecrosis[Mesh] for all databases. The inclusion criteria randomized controlled trials (RCT), as well as prospective and retrospective cohort studies published in English; MORN patients treated with 3D-CRT y IMRT. Results: 27 articles were selected from 194 initially found. 14 articles out of 27 were excluded and finally included 8 publications were included in the systematic review that were ranked according to their level of scientific evidence using the SORT criteria. Conclusions: When both RT techniques were compared; IMRT revealed a lower risk incidence of MORN development and enhanced dose constraint than 3D-CRT (less than 10%). this improvement could translate into less complications post RT treatment.