Oxidative stress in bacteria and protein damage by reactive oxygen species

The advent of O2 in the atmosphere was among the first major pollution events occurred on earth. The reaction between ferrous iron, very abundant in the reductive early atmosphere, and oxygen results in the formation of harmful superoxide and hydroxyl radicals, which affect all macromolecules (DNA,...

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Detalles Bibliográficos
Autores: Cabiscol Català, Elisa, Tamarit Sumalla, Jordi, Ros Salvador, Joaquim
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2000
País:España
Institución:Universitat de Lleida (UdL)
Repositorio:Repositori Obert UdL
OAI Identifier:oai:repositori.udl.cat:10459.1/56751
Acceso en línea:http://hdl.handle.net/10459.1/56751
Access Level:acceso abierto
Palabra clave:Oxygen
Oxidative stress
Reactive oxygen species
Protein oxidation
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spelling Oxidative stress in bacteria and protein damage by reactive oxygen speciesCabiscol Català, ElisaTamarit Sumalla, JordiRos Salvador, JoaquimOxygenOxidative stressReactive oxygen speciesProtein oxidationThe advent of O2 in the atmosphere was among the first major pollution events occurred on earth. The reaction between ferrous iron, very abundant in the reductive early atmosphere, and oxygen results in the formation of harmful superoxide and hydroxyl radicals, which affect all macromolecules (DNA, lipids and proteins). Living organisms have to build up mechanisms to protect themselves against oxidative stress, with enzymes such as catalase and superoxide dismutase, small proteins like thioredoxin and glutaredoxin, and molecules such as glutathione. Bacterial genetic responses to oxidative stress are controlled by two major transcriptional regulators (OxyR and SoxRS). This paper reviews major key points in the generation of reactive oxygen species in bacteria, defense mechanisms and genetic responses to oxidative stress. Special attention is paid to the oxidative damage to proteins.Some research work described in this review was supported in part by Grant PB94-0829-C02-02 from DGICYT of the Spanish Government, and by the Comissionat per Universitats i Recerca of the Autonomous Government of Catalonia.Springer-Verlag Ibérica2000info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://hdl.handle.net/10459.1/56751reponame:Repositori Obert UdL instname:Universitat de Lleida (UdL)InglésReproducció del document publicat a http://revistes.iec.cat/index.php/IM/article/viewFile/9235/9233International Microbiology, 2000, vol. 3, núm. 1, p. 3-8(c) Spanish Society for Microbiology, Springer-Verlag Ibérica, 2000info:eu-repo/semantics/openAccessoai:repositori.udl.cat:10459.1/567512026-06-24T12:42:17Z
dc.title.none.fl_str_mv Oxidative stress in bacteria and protein damage by reactive oxygen species
title Oxidative stress in bacteria and protein damage by reactive oxygen species
spellingShingle Oxidative stress in bacteria and protein damage by reactive oxygen species
Cabiscol Català, Elisa
Oxygen
Oxidative stress
Reactive oxygen species
Protein oxidation
title_short Oxidative stress in bacteria and protein damage by reactive oxygen species
title_full Oxidative stress in bacteria and protein damage by reactive oxygen species
title_fullStr Oxidative stress in bacteria and protein damage by reactive oxygen species
title_full_unstemmed Oxidative stress in bacteria and protein damage by reactive oxygen species
title_sort Oxidative stress in bacteria and protein damage by reactive oxygen species
dc.creator.none.fl_str_mv Cabiscol Català, Elisa
Tamarit Sumalla, Jordi
Ros Salvador, Joaquim
author Cabiscol Català, Elisa
author_facet Cabiscol Català, Elisa
Tamarit Sumalla, Jordi
Ros Salvador, Joaquim
author_role author
author2 Tamarit Sumalla, Jordi
Ros Salvador, Joaquim
author2_role author
author
dc.subject.none.fl_str_mv Oxygen
Oxidative stress
Reactive oxygen species
Protein oxidation
topic Oxygen
Oxidative stress
Reactive oxygen species
Protein oxidation
description The advent of O2 in the atmosphere was among the first major pollution events occurred on earth. The reaction between ferrous iron, very abundant in the reductive early atmosphere, and oxygen results in the formation of harmful superoxide and hydroxyl radicals, which affect all macromolecules (DNA, lipids and proteins). Living organisms have to build up mechanisms to protect themselves against oxidative stress, with enzymes such as catalase and superoxide dismutase, small proteins like thioredoxin and glutaredoxin, and molecules such as glutathione. Bacterial genetic responses to oxidative stress are controlled by two major transcriptional regulators (OxyR and SoxRS). This paper reviews major key points in the generation of reactive oxygen species in bacteria, defense mechanisms and genetic responses to oxidative stress. Special attention is paid to the oxidative damage to proteins.
publishDate 2000
dc.date.none.fl_str_mv 2000
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10459.1/56751
url http://hdl.handle.net/10459.1/56751
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Reproducció del document publicat a http://revistes.iec.cat/index.php/IM/article/viewFile/9235/9233
International Microbiology, 2000, vol. 3, núm. 1, p. 3-8
dc.rights.none.fl_str_mv (c) Spanish Society for Microbiology, Springer-Verlag Ibérica, 2000
info:eu-repo/semantics/openAccess
rights_invalid_str_mv (c) Spanish Society for Microbiology, Springer-Verlag Ibérica, 2000
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Springer-Verlag Ibérica
publisher.none.fl_str_mv Springer-Verlag Ibérica
dc.source.none.fl_str_mv reponame:Repositori Obert UdL
instname:Universitat de Lleida (UdL)
instname_str Universitat de Lleida (UdL)
reponame_str Repositori Obert UdL
collection Repositori Obert UdL
repository.name.fl_str_mv
repository.mail.fl_str_mv
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