Linking the Interatomic Exchange-Correlation Energy to Experimental J‑Coupling Constants

The main aim of the current work is to find an experimental connection to the interatomic exchange-correlation energy as defined by the energy decomposition method Interacting Quantum Atoms (IQA). A suitable candidate as (essentially) experimental quantity is the nuclear magnetic resonance (NMR) J-c...

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Autores: Alkorta, Ibon, Popelier, Paul L. A.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2023
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/286870
Acceso en línea:http://hdl.handle.net/10261/286870
Access Level:acceso abierto
Palabra clave:http://metadata.un.org/sdg/3
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http://metadata.un.org/sdg/9
http://metadata.un.org/sdg/10
http://metadata.un.org/sdg/11
http://metadata.un.org/sdg/12
http://metadata.un.org/sdg/13
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Ensure healthy lives and promote well-being for all at all ages
Ensure inclusive and equitable quality education and promote lifelong learning opportunities for all
Achieve gender equality and empower all women and girls
Ensure availability and sustainable management of water and sanitation for all
Ensure access to affordable, reliable, sustainable and modern energy for all
Promote sustained, inclusive and sustainable economic growth, full and productive employment and decent work for all
Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation
Reduce inequality within and among countries
Make cities and human settlements inclusive, safe, resilient and sustainable
Ensure sustainable consumption and production patterns
Take urgent action to combat climate change and its impacts
Conserve and sustainably use the oceans, seas and marine resources for sustainable development
Protect, restore and promote sustainable use of terrestrial ecosystems, sustainably manage forests, combat desertification, and halt and reverse land degradation and halt biodiversity loss
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spelling Linking the Interatomic Exchange-Correlation Energy to Experimental J‑Coupling ConstantsAlkorta, IbonPopelier, Paul L. A.http://metadata.un.org/sdg/3http://metadata.un.org/sdg/4http://metadata.un.org/sdg/5http://metadata.un.org/sdg/6http://metadata.un.org/sdg/7http://metadata.un.org/sdg/8http://metadata.un.org/sdg/9http://metadata.un.org/sdg/10http://metadata.un.org/sdg/11http://metadata.un.org/sdg/12http://metadata.un.org/sdg/13http://metadata.un.org/sdg/14Ensure healthy lives and promote well-being for all at all agesEnsure inclusive and equitable quality education and promote lifelong learning opportunities for allAchieve gender equality and empower all women and girlsEnsure availability and sustainable management of water and sanitation for allEnsure access to affordable, reliable, sustainable and modern energy for allPromote sustained, inclusive and sustainable economic growth, full and productive employment and decent work for allBuild resilient infrastructure, promote inclusive and sustainable industrialization and foster innovationReduce inequality within and among countriesMake cities and human settlements inclusive, safe, resilient and sustainableEnsure sustainable consumption and production patternsTake urgent action to combat climate change and its impactsConserve and sustainably use the oceans, seas and marine resources for sustainable developmentProtect, restore and promote sustainable use of terrestrial ecosystems, sustainably manage forests, combat desertification, and halt and reverse land degradation and halt biodiversity lossThe main aim of the current work is to find an experimental connection to the interatomic exchange-correlation energy as defined by the energy decomposition method Interacting Quantum Atoms (IQA). A suitable candidate as (essentially) experimental quantity is the nuclear magnetic resonance (NMR) J-coupling constant denoted 3J(H,H′), which a number of previous studies showed to correlate well with QTAIM’s delocalization index (DI), which is essentially a bond order. Inspired by Karplus equations, here, we investigate correlations between 3J(H,H′) and a relevant dihedral angle in six simple initial compounds of the shape H3C-YHn (Y = C, N, O, Si, P, and S), N- methylacetamide (as prototype of the peptide bond), and five peptide-capped amino acids (Gly, Ala, Val, Ile, and Leu) because of the protein direction of the force field FFLUX. In conclusion, except for methanol, the inter-hydrogen exchange-correlation energy Vxc(H,H′) makes the best contact with experiment, through 3J(H,H′), when multiplied with the internuclear distance RHH′.This work was carried out with financial support from the Ministerio de Ciencia, Innovación y Universidades (PID2021- 125207NB-C32) and Comunidad de Madrid (P2018/EMT- 4329 AIRTEC-CM). Gratitude is due to the CTI (CSIC) for their continued computational support. P.L.A.P. acknowledges the EPSRC for funding through the award of an Established Career Fellowship (grant EP/K005472).Peer reviewedACS PublicationsMinisterio de Ciencia, Innovación y Universidades (España)Comunidad de MadridConsejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]202320232023info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Publisher's versioninfo:eu-repo/semantics/publishedVersionhttp://hdl.handle.net/10261/286870reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Ingléshttps://doi.org/10.1021/acs.jpca.2c07693Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/2868702026-05-22T06:33:51Z
dc.title.none.fl_str_mv Linking the Interatomic Exchange-Correlation Energy to Experimental J‑Coupling Constants
title Linking the Interatomic Exchange-Correlation Energy to Experimental J‑Coupling Constants
spellingShingle Linking the Interatomic Exchange-Correlation Energy to Experimental J‑Coupling Constants
Alkorta, Ibon
http://metadata.un.org/sdg/3
http://metadata.un.org/sdg/4
http://metadata.un.org/sdg/5
http://metadata.un.org/sdg/6
http://metadata.un.org/sdg/7
http://metadata.un.org/sdg/8
http://metadata.un.org/sdg/9
http://metadata.un.org/sdg/10
http://metadata.un.org/sdg/11
http://metadata.un.org/sdg/12
http://metadata.un.org/sdg/13
http://metadata.un.org/sdg/14
Ensure healthy lives and promote well-being for all at all ages
Ensure inclusive and equitable quality education and promote lifelong learning opportunities for all
Achieve gender equality and empower all women and girls
Ensure availability and sustainable management of water and sanitation for all
Ensure access to affordable, reliable, sustainable and modern energy for all
Promote sustained, inclusive and sustainable economic growth, full and productive employment and decent work for all
Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation
Reduce inequality within and among countries
Make cities and human settlements inclusive, safe, resilient and sustainable
Ensure sustainable consumption and production patterns
Take urgent action to combat climate change and its impacts
Conserve and sustainably use the oceans, seas and marine resources for sustainable development
Protect, restore and promote sustainable use of terrestrial ecosystems, sustainably manage forests, combat desertification, and halt and reverse land degradation and halt biodiversity loss
title_short Linking the Interatomic Exchange-Correlation Energy to Experimental J‑Coupling Constants
title_full Linking the Interatomic Exchange-Correlation Energy to Experimental J‑Coupling Constants
title_fullStr Linking the Interatomic Exchange-Correlation Energy to Experimental J‑Coupling Constants
title_full_unstemmed Linking the Interatomic Exchange-Correlation Energy to Experimental J‑Coupling Constants
title_sort Linking the Interatomic Exchange-Correlation Energy to Experimental J‑Coupling Constants
dc.creator.none.fl_str_mv Alkorta, Ibon
Popelier, Paul L. A.
author Alkorta, Ibon
author_facet Alkorta, Ibon
Popelier, Paul L. A.
author_role author
author2 Popelier, Paul L. A.
author2_role author
dc.contributor.none.fl_str_mv Ministerio de Ciencia, Innovación y Universidades (España)
Comunidad de Madrid
Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
dc.subject.none.fl_str_mv http://metadata.un.org/sdg/3
http://metadata.un.org/sdg/4
http://metadata.un.org/sdg/5
http://metadata.un.org/sdg/6
http://metadata.un.org/sdg/7
http://metadata.un.org/sdg/8
http://metadata.un.org/sdg/9
http://metadata.un.org/sdg/10
http://metadata.un.org/sdg/11
http://metadata.un.org/sdg/12
http://metadata.un.org/sdg/13
http://metadata.un.org/sdg/14
Ensure healthy lives and promote well-being for all at all ages
Ensure inclusive and equitable quality education and promote lifelong learning opportunities for all
Achieve gender equality and empower all women and girls
Ensure availability and sustainable management of water and sanitation for all
Ensure access to affordable, reliable, sustainable and modern energy for all
Promote sustained, inclusive and sustainable economic growth, full and productive employment and decent work for all
Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation
Reduce inequality within and among countries
Make cities and human settlements inclusive, safe, resilient and sustainable
Ensure sustainable consumption and production patterns
Take urgent action to combat climate change and its impacts
Conserve and sustainably use the oceans, seas and marine resources for sustainable development
Protect, restore and promote sustainable use of terrestrial ecosystems, sustainably manage forests, combat desertification, and halt and reverse land degradation and halt biodiversity loss
topic http://metadata.un.org/sdg/3
http://metadata.un.org/sdg/4
http://metadata.un.org/sdg/5
http://metadata.un.org/sdg/6
http://metadata.un.org/sdg/7
http://metadata.un.org/sdg/8
http://metadata.un.org/sdg/9
http://metadata.un.org/sdg/10
http://metadata.un.org/sdg/11
http://metadata.un.org/sdg/12
http://metadata.un.org/sdg/13
http://metadata.un.org/sdg/14
Ensure healthy lives and promote well-being for all at all ages
Ensure inclusive and equitable quality education and promote lifelong learning opportunities for all
Achieve gender equality and empower all women and girls
Ensure availability and sustainable management of water and sanitation for all
Ensure access to affordable, reliable, sustainable and modern energy for all
Promote sustained, inclusive and sustainable economic growth, full and productive employment and decent work for all
Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation
Reduce inequality within and among countries
Make cities and human settlements inclusive, safe, resilient and sustainable
Ensure sustainable consumption and production patterns
Take urgent action to combat climate change and its impacts
Conserve and sustainably use the oceans, seas and marine resources for sustainable development
Protect, restore and promote sustainable use of terrestrial ecosystems, sustainably manage forests, combat desertification, and halt and reverse land degradation and halt biodiversity loss
description The main aim of the current work is to find an experimental connection to the interatomic exchange-correlation energy as defined by the energy decomposition method Interacting Quantum Atoms (IQA). A suitable candidate as (essentially) experimental quantity is the nuclear magnetic resonance (NMR) J-coupling constant denoted 3J(H,H′), which a number of previous studies showed to correlate well with QTAIM’s delocalization index (DI), which is essentially a bond order. Inspired by Karplus equations, here, we investigate correlations between 3J(H,H′) and a relevant dihedral angle in six simple initial compounds of the shape H3C-YHn (Y = C, N, O, Si, P, and S), N- methylacetamide (as prototype of the peptide bond), and five peptide-capped amino acids (Gly, Ala, Val, Ile, and Leu) because of the protein direction of the force field FFLUX. In conclusion, except for methanol, the inter-hydrogen exchange-correlation energy Vxc(H,H′) makes the best contact with experiment, through 3J(H,H′), when multiplied with the internuclear distance RHH′.
publishDate 2023
dc.date.none.fl_str_mv 2023
2023
2023
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
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info:eu-repo/semantics/publishedVersion
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dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/286870
url http://hdl.handle.net/10261/286870
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv https://doi.org/10.1021/acs.jpca.2c07693

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