Abnormalities of sodium excretion and other disorders of renal function in fulminant hepatic failure

Renal function was evaluated in 40 patients with fulminant hepatic failure, They were divided into two groups on the basis of glomerular filtration rates greater than 40 ml/min or less than 25 ml/min. A number of patients in group 1 had markedly abnormal renal retention of sodium together with a red...

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Detalles Bibliográficos
Autores: Wilkinson, S. P., Arroyo, Vicente, Moodie, Helen, Blendis, L. M., Williams, Roger
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:1976
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/18675
Acceso en línea:https://hdl.handle.net/2445/18675
Access Level:acceso abierto
Palabra clave:Malalties del fetge
Ronyó
Sodi en l'organisme
Liver diseases
Kidney
Sodium in the body
Descripción
Sumario:Renal function was evaluated in 40 patients with fulminant hepatic failure, They were divided into two groups on the basis of glomerular filtration rates greater than 40 ml/min or less than 25 ml/min. A number of patients in group 1 had markedly abnormal renal retention of sodium together with a reduced free water clearance and low potassium excretion which could be explained by increased proximal tubular reabsorption of sodium. The patients in group 2 had evidence that renal tubular integrity was maintained when the glomerular filtration rate was greater than or equal ml/min (functional renal failure), but evidence of tubular damage was present when this was less than 3 ml/min (acute tubular necrosis).