Complex pathogens in infective endocarditis
Endocarditis; Diagnosis; Treatment
| Autores: | , , , , , |
|---|---|
| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2023 |
| País: | España |
| Institución: | Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya) |
| Repositorio: | Recercat. Dipósit de la Recerca de Catalunya |
| OAI Identifier: | oai:recercat.cat:11351/10317 |
| Acceso en línea: | https://hdl.handle.net/11351/10317 http://hdl.handle.net/11351/10317 |
| Access Level: | acceso abierto |
| Palabra clave: | Endocarditis bacteriana - Tractament Medicaments antiinfecciosos - Ús terapèutic DISEASES::Cardiovascular Diseases::Heart Diseases::Endocarditis Other subheadings::Other subheadings::Other subheadings::/drug therapy CHEMICALS AND DRUGS::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Anti-Infective Agents Other subheadings::Other subheadings::/therapeutic use ENFERMEDADES::enfermedades cardiovasculares::enfermedades cardíacas::endocarditis Otros calificadores::Otros calificadores::Otros calificadores::/farmacoterapia COMPUESTOS QUÍMICOS Y DROGAS::acciones y usos químicos::acciones farmacológicas::usos terapéuticos::antiinfecciosos Otros calificadores::Otros calificadores::/uso terapéutico |
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Complex pathogens in infective endocarditis |
| title |
Complex pathogens in infective endocarditis |
| spellingShingle |
Complex pathogens in infective endocarditis Escolà-Vergé, Laura Endocarditis bacteriana - Tractament Medicaments antiinfecciosos - Ús terapèutic DISEASES::Cardiovascular Diseases::Heart Diseases::Endocarditis Other subheadings::Other subheadings::Other subheadings::/drug therapy CHEMICALS AND DRUGS::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Anti-Infective Agents Other subheadings::Other subheadings::/therapeutic use ENFERMEDADES::enfermedades cardiovasculares::enfermedades cardíacas::endocarditis Otros calificadores::Otros calificadores::Otros calificadores::/farmacoterapia COMPUESTOS QUÍMICOS Y DROGAS::acciones y usos químicos::acciones farmacológicas::usos terapéuticos::antiinfecciosos Otros calificadores::Otros calificadores::/uso terapéutico |
| title_short |
Complex pathogens in infective endocarditis |
| title_full |
Complex pathogens in infective endocarditis |
| title_fullStr |
Complex pathogens in infective endocarditis |
| title_full_unstemmed |
Complex pathogens in infective endocarditis |
| title_sort |
Complex pathogens in infective endocarditis |
| dc.creator.none.fl_str_mv |
Escolà-Vergé, Laura Albert, Roque Pizzi, María Nazarena González-López, Juan José Almirante, Benito Fernández-Hidalgo, Nuria |
| author |
Escolà-Vergé, Laura |
| author_facet |
Escolà-Vergé, Laura Albert, Roque Pizzi, María Nazarena González-López, Juan José Almirante, Benito Fernández-Hidalgo, Nuria |
| author_role |
author |
| author2 |
Albert, Roque Pizzi, María Nazarena González-López, Juan José Almirante, Benito Fernández-Hidalgo, Nuria |
| author2_role |
author author author author author |
| dc.contributor.none.fl_str_mv |
Institut Català de la Salut [Escolà-Vergé L, Almirante B, Fernández-Hidalgo N] Servei de Malalties Infeccioses, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Departament de Medicina, Universitat Autònoma de Barcelona, Bellaterra, Spain. Spanish Network for the Research in Infectious Diseases (REIPI RD16/0016/0003), Instituto de Salud Carlos III, Madrid, Spain. CIBERIFEC, ISCIII- CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid, Spain. Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. [Roque A] Departament de Medicina, Universitat Autònoma de Barcelona, Bellaterra, Spain. Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Servei de Radiologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. IDI (Institut de Diagnòstic per la Imatge), Barcelona, Spain. [Pizzi MN] Departament de Medicina, Universitat Autònoma de Barcelona, Bellaterra, Spain. Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Servei de Cardiologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Centro de Investigación Biomédica en Red en Enfermedades Cardiovasculares (CIBERCV), Madrid, Spain. [González-López JJ] Spanish Network for the Research in Infectious Diseases (REIPI RD16/0016/0003), Instituto de Salud Carlos III, Madrid, Spain. CIBERIFEC, ISCIII- CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid, Spain. Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Servei de Microbiologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Bellaterra, Spain Vall d'Hebron Barcelona Hospital Campus |
| dc.subject.none.fl_str_mv |
Endocarditis bacteriana - Tractament Medicaments antiinfecciosos - Ús terapèutic DISEASES::Cardiovascular Diseases::Heart Diseases::Endocarditis Other subheadings::Other subheadings::Other subheadings::/drug therapy CHEMICALS AND DRUGS::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Anti-Infective Agents Other subheadings::Other subheadings::/therapeutic use ENFERMEDADES::enfermedades cardiovasculares::enfermedades cardíacas::endocarditis Otros calificadores::Otros calificadores::Otros calificadores::/farmacoterapia COMPUESTOS QUÍMICOS Y DROGAS::acciones y usos químicos::acciones farmacológicas::usos terapéuticos::antiinfecciosos Otros calificadores::Otros calificadores::/uso terapéutico |
| topic |
Endocarditis bacteriana - Tractament Medicaments antiinfecciosos - Ús terapèutic DISEASES::Cardiovascular Diseases::Heart Diseases::Endocarditis Other subheadings::Other subheadings::Other subheadings::/drug therapy CHEMICALS AND DRUGS::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Anti-Infective Agents Other subheadings::Other subheadings::/therapeutic use ENFERMEDADES::enfermedades cardiovasculares::enfermedades cardíacas::endocarditis Otros calificadores::Otros calificadores::Otros calificadores::/farmacoterapia COMPUESTOS QUÍMICOS Y DROGAS::acciones y usos químicos::acciones farmacológicas::usos terapéuticos::antiinfecciosos Otros calificadores::Otros calificadores::/uso terapéutico |
| description |
Endocarditis; Diagnosis; Treatment |
| publishDate |
2023 |
| dc.date.none.fl_str_mv |
2023 2023 2023 |
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info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
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article |
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publishedVersion |
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https://hdl.handle.net/11351/10317 http://hdl.handle.net/11351/10317 |
| url |
https://hdl.handle.net/11351/10317 http://hdl.handle.net/11351/10317 |
| dc.language.none.fl_str_mv |
Inglés |
| language_invalid_str_mv |
Inglés |
| dc.relation.none.fl_str_mv |
Vessel Plus;7 http://dx.doi.org/10.20517/2574-1209.2022.51 |
| dc.rights.none.fl_str_mv |
Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ info:eu-repo/semantics/openAccess |
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Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ |
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openAccess |
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application/pdf |
| dc.publisher.none.fl_str_mv |
OAE Publishing |
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OAE Publishing |
| dc.source.none.fl_str_mv |
Scientia reponame:Recercat. Dipósit de la Recerca de Catalunya instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya) |
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Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya) |
| reponame_str |
Recercat. Dipósit de la Recerca de Catalunya |
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Recercat. Dipósit de la Recerca de Catalunya |
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1869420009202122752 |
| spelling |
Complex pathogens in infective endocarditisEscolà-Vergé, LauraAlbert, RoquePizzi, María NazarenaGonzález-López, Juan JoséAlmirante, BenitoFernández-Hidalgo, NuriaEndocarditis bacteriana - TractamentMedicaments antiinfecciosos - Ús terapèuticDISEASES::Cardiovascular Diseases::Heart Diseases::EndocarditisOther subheadings::Other subheadings::Other subheadings::/drug therapyCHEMICALS AND DRUGS::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Anti-Infective AgentsOther subheadings::Other subheadings::/therapeutic useENFERMEDADES::enfermedades cardiovasculares::enfermedades cardíacas::endocarditisOtros calificadores::Otros calificadores::Otros calificadores::/farmacoterapiaCOMPUESTOS QUÍMICOS Y DROGAS::acciones y usos químicos::acciones farmacológicas::usos terapéuticos::antiinfecciososOtros calificadores::Otros calificadores::/uso terapéuticoEndocarditis; Diagnosis; TreatmentEndocarditis; Diagnóstico; TratamientoEndocarditis; Diagnòstic; TractamentInfective endocarditis (IE) is a complex disease whose prognosis depends on the causative microorganism, among other factors. The latter can be difficult to identify and/or treat. In this narrative review, we identify knowledge gaps in the diagnosis and antimicrobial treatment of IE, and attempt to shed light on current questions. Specifically, we: (1) analyze the factors that may hinder the microbiological diagnosis of blood culture-negative IE, as well as the role of new imaging techniques, such as 18F-fluorodeoxyglucose ([18F]FDG PET/CT), in the diagnostic capacity of this disease, understanding their advantages and assuming their limitations; (2) discuss the therapeutic approach to various difficult-to-treat microorganisms. In particular, we focus on the treatment of staphylococcal IE since, at present, staphylococci are the most frequent cause of IE in developed countries and staphylococcal IE is one of those with the highest short- and long-term mortality. We critically evaluate the current evidence on combination therapy and address the occurrence of serious side effects, an aspect that is often overlooked owing to the severity of the infection; and (3) emphasize the need for home antimicrobial treatment of patients with IE, as these are fragile people who benefit from an early return to their environment. This poses undoubted logistical challenges and requires robust evidence to ensure the best short- and long-term outcomes.Laura Escolà-Vergé has a Juan Rodés contract in the call 2020 Strategic Action Health from the Instituto de Salud Carlos III of Spanish Health Ministry for the years 2021-2024. This research was supported by CIBER-Consorcio Centro de Investigación Biomédica en Red (CB 2021), Instituto de Salud Carlos III, Ministerio de Ciencia e Innovación and Unión Europea - NextGenerationEU.OAE PublishingInstitut Català de la Salut[Escolà-Vergé L, Almirante B, Fernández-Hidalgo N] Servei de Malalties Infeccioses, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Departament de Medicina, Universitat Autònoma de Barcelona, Bellaterra, Spain. Spanish Network for the Research in Infectious Diseases (REIPI RD16/0016/0003), Instituto de Salud Carlos III, Madrid, Spain. CIBERIFEC, ISCIII- CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid, Spain. Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. [Roque A] Departament de Medicina, Universitat Autònoma de Barcelona, Bellaterra, Spain. Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Servei de Radiologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. IDI (Institut de Diagnòstic per la Imatge), Barcelona, Spain. [Pizzi MN] Departament de Medicina, Universitat Autònoma de Barcelona, Bellaterra, Spain. Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Servei de Cardiologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Centro de Investigación Biomédica en Red en Enfermedades Cardiovasculares (CIBERCV), Madrid, Spain. [González-López JJ] Spanish Network for the Research in Infectious Diseases (REIPI RD16/0016/0003), Instituto de Salud Carlos III, Madrid, Spain. CIBERIFEC, ISCIII- CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid, Spain. Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Servei de Microbiologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Bellaterra, SpainVall d'Hebron Barcelona Hospital Campus202320232023info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://hdl.handle.net/11351/10317http://hdl.handle.net/11351/10317Scientiareponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésVessel Plus;7http://dx.doi.org/10.20517/2574-1209.2022.51Attribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:recercat.cat:11351/103172026-05-29T05:05:01Z |
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