rs12416605:C>T in MIR938 associates with gastric cancer through affecting the regulation of the CXCL12 chemokine gene

[Background] MicroRNAs are small regulatory RNAs with important roles in carcinogenesis. Genetic variants in these regulatory molecules may contribute to disease. We aim to identify allelic variants in microRNAs as susceptibility factors to gastric cancer using association studies and functional app...

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Detalles Bibliográficos
Autores: Torruella-Loran, Ignasi, Ramírez Viña, María Karla, Zapata-Contreras, Daniel, Muñoz, Xavier, García-Ramallo, Eva, Bonet, Catalina, Gonzalez, Carlos A., Sala, Núria, Espinosa-Parrilla, Yolanda
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2019
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/207034
Acceso en línea:http://hdl.handle.net/10261/207034
Access Level:acceso abierto
Palabra clave:Functional SNV
Gastric cancer
Gene regulation
Genetic susceptibility
MicroRNA
Descripción
Sumario:[Background] MicroRNAs are small regulatory RNAs with important roles in carcinogenesis. Genetic variants in these regulatory molecules may contribute to disease. We aim to identify allelic variants in microRNAs as susceptibility factors to gastric cancer using association studies and functional approaches.

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