EXIT procedure in twin pregnancy: a series of three cases from a single center

Background: Indications for the ex utero intrapartum therapy (EXIT) procedure have evolved and nowadays in addition to secure the airway, obtain vascular access, administer surfactant and other resuscitation medications, EXIT is used to resect cervical or thoracic masses, for extracorporeal membrane...

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Detalles Bibliográficos
Autores: García Díaz, Lutgardo, Agustín, Juan Carlos de, Ontanilla, Antonio, Marenco, María Luisa, Pavón, Antonio, Losada, Antonio, Antiñolo Gil, Guillermo
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2014
País:España
Institución:Universidad de Sevilla (US)
Repositorio:idUS. Depósito de Investigación de la Universidad de Sevilla
OAI Identifier:oai:idus.us.es:11441/111879
Acceso en línea:https://hdl.handle.net/11441/111879
https://doi.org/10.1186/1471-2393-14-252
Access Level:acceso abierto
Palabra clave:Prenatal diagnosis
Fetal medicine
Fetal intervention
Twin pregnancy
Ex utero intrapartum therapy
EXIT procedure
Descripción
Sumario:Background: Indications for the ex utero intrapartum therapy (EXIT) procedure have evolved and nowadays in addition to secure the airway, obtain vascular access, administer surfactant and other resuscitation medications, EXIT is used to resect cervical or thoracic masses, for extracorporeal membrane circulation (ECMO) cannulation, as well as to rescue maximum intra-thoracic space for ventilation of the remaining functional lung tissue or in cases in which resuscitation of the neonate may be compromised. EXIT procedure in twin pregnancy has been rarely reported and some doubts have been raised about its strategy and safety in such cases. Methods: We reviewed the medical records of 3 twin pregnancy cases where the EXIT procedure have been performed in our center. Results: The mean gestational age at EXIT procedure was 34 + 4 weeks. In two out the three EXIT procedures, the affected twin was delivered first. The average time on placental bypass was 9 minutes. There were no fetal or maternal complications related to the EXIT procedure. All newborns are currently doing well. Conclusion: In twin pregnancies, prenatal diagnosis combined with the EXIT procedure permits the formulation of a controlled delivery strategy to secure both newborns outcome. In those pregnancies, if intervention can be accomplished without compromise of the normal twin, EXIT can be considered. Our results support that EXIT procedure, if properly planned, safely provides a good outcome for both the fetuses as well as the mother.