Bifunctional thiourea-modified polymers of intrinsic microporosity for enantioselective α-amination of 3-aryl-2-oxindoles in batch and flow conditions

Producción Científica

Bibliographic Details
Authors: Martín Maroto, Laura, Maestro Fernández, Alicia, Andrés García, José María, Pedrosa Sáez, Rafael
Format: article
Status:Versión aceptada para publicación
Publication Date:2020
Country:España
Institution:Universidad de Valladolid
Repository:UVaDOC. Repositorio Documental de la Universidad de Valladolid
OAI Identifier:oai:uvadoc.uva.es:10324/43682
Online Access:https://doi.org/10.1039/D0OB01373K
http://uvadoc.uva.es/handle/10324/43682
Access Level:Open access
Keyword:Polímeros
Polymers
2306 Química Orgánica
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spelling Bifunctional thiourea-modified polymers of intrinsic microporosity for enantioselective α-amination of 3-aryl-2-oxindoles in batch and flow conditionsMartín Maroto, LauraMaestro Fernández, AliciaAndrés García, José MaríaPedrosa Sáez, RafaelPolímerosPolymers2306 Química OrgánicaProducción CientíficaTwo novel polymers of intrinsic microporosity decorated with chiral thioureas have been used as recoverable organocatalysts in enantioselective α-amination of 3-aryl-substituted oxindoles, creating a quaternary stereocenter. Both catalysts were able to promote the reaction in excellent yields and good enantioselection. Catalyst II, with a pyridyl nucleus, was used in recycling experiments maintaining the activity without additional reactivation, and in flow processes allowing the synthesis of the amination product in multigram scale.Junta de Castilla y León (Projects FEDER VA115P17, and VA149G18)Royal Society of Chemistry2020info:eu-repo/semantics/articleinfo:eu-repo/semantics/acceptedVersionapplication/pdfhttps://doi.org/10.1039/D0OB01373Khttp://uvadoc.uva.es/handle/10324/43682reponame:UVaDOC. Repositorio Documental de la Universidad de Valladolidinstname:Universidad de ValladolidIngléshttps://pubs.rsc.org/en/content/articlelanding/2020/OB/D0OB01373K#!divAbstractinfo:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-nd/4.0/oai:uvadoc.uva.es:10324/436822026-06-13T12:44:47Z
dc.title.none.fl_str_mv Bifunctional thiourea-modified polymers of intrinsic microporosity for enantioselective α-amination of 3-aryl-2-oxindoles in batch and flow conditions
title Bifunctional thiourea-modified polymers of intrinsic microporosity for enantioselective α-amination of 3-aryl-2-oxindoles in batch and flow conditions
spellingShingle Bifunctional thiourea-modified polymers of intrinsic microporosity for enantioselective α-amination of 3-aryl-2-oxindoles in batch and flow conditions
Martín Maroto, Laura
Polímeros
Polymers
2306 Química Orgánica
title_short Bifunctional thiourea-modified polymers of intrinsic microporosity for enantioselective α-amination of 3-aryl-2-oxindoles in batch and flow conditions
title_full Bifunctional thiourea-modified polymers of intrinsic microporosity for enantioselective α-amination of 3-aryl-2-oxindoles in batch and flow conditions
title_fullStr Bifunctional thiourea-modified polymers of intrinsic microporosity for enantioselective α-amination of 3-aryl-2-oxindoles in batch and flow conditions
title_full_unstemmed Bifunctional thiourea-modified polymers of intrinsic microporosity for enantioselective α-amination of 3-aryl-2-oxindoles in batch and flow conditions
title_sort Bifunctional thiourea-modified polymers of intrinsic microporosity for enantioselective α-amination of 3-aryl-2-oxindoles in batch and flow conditions
dc.creator.none.fl_str_mv Martín Maroto, Laura
Maestro Fernández, Alicia
Andrés García, José María
Pedrosa Sáez, Rafael
author Martín Maroto, Laura
author_facet Martín Maroto, Laura
Maestro Fernández, Alicia
Andrés García, José María
Pedrosa Sáez, Rafael
author_role author
author2 Maestro Fernández, Alicia
Andrés García, José María
Pedrosa Sáez, Rafael
author2_role author
author
author
dc.subject.none.fl_str_mv Polímeros
Polymers
2306 Química Orgánica
topic Polímeros
Polymers
2306 Química Orgánica
description Producción Científica
publishDate 2020
dc.date.none.fl_str_mv 2020
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/acceptedVersion
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv https://doi.org/10.1039/D0OB01373K
http://uvadoc.uva.es/handle/10324/43682
url https://doi.org/10.1039/D0OB01373K
http://uvadoc.uva.es/handle/10324/43682
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv https://pubs.rsc.org/en/content/articlelanding/2020/OB/D0OB01373K#!divAbstract
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Royal Society of Chemistry
publisher.none.fl_str_mv Royal Society of Chemistry
dc.source.none.fl_str_mv reponame:UVaDOC. Repositorio Documental de la Universidad de Valladolid
instname:Universidad de Valladolid
instname_str Universidad de Valladolid
reponame_str UVaDOC. Repositorio Documental de la Universidad de Valladolid
collection UVaDOC. Repositorio Documental de la Universidad de Valladolid
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869419874931965952
score 15,301603

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