Supplementary information: Role of the Nucleotide Excision Repair Endonuclease XPF in the Kinetoplastid Parasite Trypanosoma brucei

Figure S1. Full size images of western blots presented in Figure 3 (panel C) of the manuscript. Figure S2. Detection of pyrimidine dimers (PD) by immunofluorescence microscopy. Figure S3. Proliferation assay of NER-defective and parental parasites exposed to genotoxic compounds. Figure S4. Full size...

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Detalhes bibliográficos
Autores: Gómez-Liñán, Claudia, Sáez-Maldonado, María, Montosa-Hidalgo, Laura, Ruiz-Pérez, Luis Miguel, González-Pacanowska, Dolores, Vidal, Antonio E.
Formato: conjunto de datos
Fecha de publicación:2025
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/399683
Acesso em linha:http://hdl.handle.net/10261/399683
Access Level:acceso abierto
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spelling Supplementary information: Role of the Nucleotide Excision Repair Endonuclease XPF in the Kinetoplastid Parasite Trypanosoma bruceiGómez-Liñán, ClaudiaSáez-Maldonado, MaríaMontosa-Hidalgo, LauraRuiz-Pérez, Luis MiguelGonzález-Pacanowska, DoloresVidal, Antonio E.Figure S1. Full size images of western blots presented in Figure 3 (panel C) of the manuscript. Figure S2. Detection of pyrimidine dimers (PD) by immunofluorescence microscopy. Figure S3. Proliferation assay of NER-defective and parental parasites exposed to genotoxic compounds. Figure S4. Full size images of western blots presented in Figure 6 of the manuscript. Figure S5. Detection of TbXPF in the nucleolar region using a second monoclonal anti-myc tag antibody (clone 4A6). Figure S6. Full size images of western blots presented in Figure 7 of the manuscript. Table S1. List of oligonucleotides used in this study.Peer reviewedSpringer NatureVidal, Antonio E. [0000-0001-9491-8901]Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]202520252025info:eu-repo/semantics/datasethttp://purl.org/coar/resource_type/c_ddb1application/mswordhttp://hdl.handle.net/10261/399683reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)InglésGómez-Liñán, Claudia; Sáez-Maldonado, María; Montosa-Hidalgo, Laura; Ruiz-Pérez, Luis Miguel; González-Pacanowska, Dolores; Vidal, Antonio E.. Role of the nucleotide excision repair endonuclease XPF in the kinetoplastid parasite Trypanosoma brucei. https://doi.org/10.1038/s41598-025-08659-y. http://hdl.handle.net/10261/399615https://doi.org/10.1038/s41598-025-08659-ySíinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/3996832026-05-22T06:33:51Z
dc.title.none.fl_str_mv Supplementary information: Role of the Nucleotide Excision Repair Endonuclease XPF in the Kinetoplastid Parasite Trypanosoma brucei
title Supplementary information: Role of the Nucleotide Excision Repair Endonuclease XPF in the Kinetoplastid Parasite Trypanosoma brucei
spellingShingle Supplementary information: Role of the Nucleotide Excision Repair Endonuclease XPF in the Kinetoplastid Parasite Trypanosoma brucei
Gómez-Liñán, Claudia
title_short Supplementary information: Role of the Nucleotide Excision Repair Endonuclease XPF in the Kinetoplastid Parasite Trypanosoma brucei
title_full Supplementary information: Role of the Nucleotide Excision Repair Endonuclease XPF in the Kinetoplastid Parasite Trypanosoma brucei
title_fullStr Supplementary information: Role of the Nucleotide Excision Repair Endonuclease XPF in the Kinetoplastid Parasite Trypanosoma brucei
title_full_unstemmed Supplementary information: Role of the Nucleotide Excision Repair Endonuclease XPF in the Kinetoplastid Parasite Trypanosoma brucei
title_sort Supplementary information: Role of the Nucleotide Excision Repair Endonuclease XPF in the Kinetoplastid Parasite Trypanosoma brucei
dc.creator.none.fl_str_mv Gómez-Liñán, Claudia
Sáez-Maldonado, María
Montosa-Hidalgo, Laura
Ruiz-Pérez, Luis Miguel
González-Pacanowska, Dolores
Vidal, Antonio E.
author Gómez-Liñán, Claudia
author_facet Gómez-Liñán, Claudia
Sáez-Maldonado, María
Montosa-Hidalgo, Laura
Ruiz-Pérez, Luis Miguel
González-Pacanowska, Dolores
Vidal, Antonio E.
author_role author
author2 Sáez-Maldonado, María
Montosa-Hidalgo, Laura
Ruiz-Pérez, Luis Miguel
González-Pacanowska, Dolores
Vidal, Antonio E.
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Vidal, Antonio E. [0000-0001-9491-8901]
Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
description Figure S1. Full size images of western blots presented in Figure 3 (panel C) of the manuscript. Figure S2. Detection of pyrimidine dimers (PD) by immunofluorescence microscopy. Figure S3. Proliferation assay of NER-defective and parental parasites exposed to genotoxic compounds. Figure S4. Full size images of western blots presented in Figure 6 of the manuscript. Figure S5. Detection of TbXPF in the nucleolar region using a second monoclonal anti-myc tag antibody (clone 4A6). Figure S6. Full size images of western blots presented in Figure 7 of the manuscript. Table S1. List of oligonucleotides used in this study.
publishDate 2025
dc.date.none.fl_str_mv 2025
2025
2025
dc.type.none.fl_str_mv info:eu-repo/semantics/dataset
http://purl.org/coar/resource_type/c_ddb1
format dataset
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/399683
url http://hdl.handle.net/10261/399683
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Gómez-Liñán, Claudia; Sáez-Maldonado, María; Montosa-Hidalgo, Laura; Ruiz-Pérez, Luis Miguel; González-Pacanowska, Dolores; Vidal, Antonio E.. Role of the nucleotide excision repair endonuclease XPF in the kinetoplastid parasite Trypanosoma brucei. https://doi.org/10.1038/s41598-025-08659-y. http://hdl.handle.net/10261/399615
https://doi.org/10.1038/s41598-025-08659-y
Sí
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/msword
dc.publisher.none.fl_str_mv Springer Nature
publisher.none.fl_str_mv Springer Nature
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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