Bioinspired metal-based oxidants: selectivity in catalytic hydroxylation of aliphatic C-H bonds and insight into the reactivity of oxoiron species
Selective oxidation of C-H bonds is an important reaction, as it can disclose novel synthetic strategies to get functionalized products through efficient paths. Nonetheless, due to the inert character of C-H bonds, the use of powerful oxidants is needed. In addition, achieving selectivity in such re...
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| Tipo de recurso: | tesis doctoral |
| Estado: | Versión publicada |
| Fecha de publicación: | 2020 |
| País: | España |
| Institución: | CBUC, CESCA |
| Repositorio: | TDR. Tesis Doctorales en Red |
| OAI Identifier: | oai:www.tdx.cat:10803/671447 |
| Acceso en línea: | http://hdl.handle.net/10803/671447 |
| Access Level: | acceso abierto |
| Palabra clave: | Enllaç C-H Enlace C-H C-H bond Oxidació selectiva Oxidación selectiva Selective oxidation Complexos bioinspirats Complejos bioinspirados Bioinspired complexes Oxoiron species Hidroxilació Hidroxilación Hydroxylation Catalitzadors Catalizadores Catalysts 546 |
| Sumario: | Selective oxidation of C-H bonds is an important reaction, as it can disclose novel synthetic strategies to get functionalized products through efficient paths. Nonetheless, due to the inert character of C-H bonds, the use of powerful oxidants is needed. In addition, achieving selectivity in such reactions is difficult. In that regard, nature can be taken as inspiration, since oxidation reactions are efficiently and selectively performed by iron-dependent oxygenases. Thus, in order to develop novel methodologies, bioinspired complexes have been explored as oxidation catalysts. In this line, in this thesis hydroxylation of C-H bonds catalyzed by bioinspired iron and manganese complexes has been first investigated. Subsequently, being mechanistic understanding important for the design of efficient catalysts, high-valent oxoiron compounds have been investigated to deeper comprehend how to modulate their oxidative ability |
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