Application of NMR techniques to the study of molecular recognition of carbohydrates by immune system proteins and proteins of viral origin

Carbohydrates play an important role in both everyday life and health-related situations. They are found in a wide variety of significant biological processes and play an essential role in molecular recognition in physiological and pathological events. Understanding the interactions in which carbohy...

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Detalles Bibliográficos
Autor: Pereda Hernández, Amaia
Tipo de recurso: tesis doctoral
Fecha de publicación:2025
País:España
Institución:Universidad Complutense de Madrid (UCM)
Repositorio:Docta Complutense
Idioma:inglés
OAI Identifier:oai:docta.ucm.es:20.500.14352/117896
Acceso en línea:https://hdl.handle.net/20.500.14352/117896
Access Level:acceso abierto
Palabra clave:612.396(043.2)
Carbohidratos
Resonancia magnética nuclear
Nuclear magnetic resonance
Carbohydrate
Bioquímica (Farmacia)
Biología molecular (Farmacia)
2403 Bioquímica
2415 Biología Molecular
Descripción
Sumario:Carbohydrates play an important role in both everyday life and health-related situations. They are found in a wide variety of significant biological processes and play an essential role in molecular recognition in physiological and pathological events. Understanding the interactions in which carbohydrates are involved is therefore crucial for gaining insight into these connections. In order to monitor these interactions, it is essential to know the possible carbohydrate-protein molecular recognition processes.Therefore, the main objective of this thesis has been to apply and develop strategies based on nuclear magnetic resonance (NMR) to elucidate the interactions of the target systems in which carbohydrates are involved...