Capsule switching among C:2b:P1.2,5 meningococcal epidemic strains after mass immunization campaign, Spain
A mass immunization campaign for 18-month to 19-year-olds was undertaken in Spain in 1996-1997 because of an epidemic of serogroup C meningococcal disease associated with a C:2b:P1.2,5 strain belonging to the A4 lineage. Surveillance for the "capsule-switching" phenomenon producing B:2b:P1...
| Autores: | , , , , , |
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| Tipo de recurso: | artículo |
| Fecha de publicación: | 2002 |
| País: | España |
| Institución: | Instituto de Salud Carlos III (ISCIII) |
| Repositorio: | Repisalud |
| Idioma: | inglés |
| OAI Identifier: | oai:repisalud.isciii.es:20.500.12105/6993 |
| Acceso en línea: | http://hdl.handle.net/20.500.12105/6993 |
| Access Level: | acceso abierto |
| Palabra clave: | Adolescent Adult Bacterial Capsules Child Child, Preschool Electrophoresis, Gel, Pulsed-Field Humans Infant Mass Vaccination Meningitis, Meningococcal Polysaccharides, Bacterial Spain |
| Sumario: | A mass immunization campaign for 18-month to 19-year-olds was undertaken in Spain in 1996-1997 because of an epidemic of serogroup C meningococcal disease associated with a C:2b:P1.2,5 strain belonging to the A4 lineage. Surveillance for the "capsule-switching" phenomenon producing B:2b:P1.2,5 isolates was undertaken. Of 2,975 meningococci characterized, B:2b:P1.2,5 and B:2b:P1.2 antigenic combinations were found in 18 isolates; 15 meningococci were defined as serogroup B belonging to the A4 lineage. |
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