Improving Mycoplasma hyopneumoniae diagnostic capabilities by harnessing the infection dynamics

Mycoplasma hyopneumoniae remains one of the most problematic bacterial pathogens for pig production. Despite an abundance of observational and laboratory testing capabilities for this organism, diagnostic interpretation of test results can be challenging and ambiguous. This is partly explained by th...

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Detalhes bibliográficos
Autores: Garcia Morante, Beatriz, Maes, Dominiek, Sibila, Marina, Betlach, Alyssa M., Sponheim, Amanda Amanda, Canturri, Albert, Pieters, Maria
Tipo de documento: artigo
Data de publicação:2022
País:España
Recursos:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositório:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:20.500.12327/1952
Acesso em linha:http://hdl.handle.net/20.500.12327/1952
https://doi.org/10.1016/j.tvjl.2022.105877
Access Level:Acceso aberto
Palavra-chave:619
Descrição
Resumo:Mycoplasma hyopneumoniae remains one of the most problematic bacterial pathogens for pig production. Despite an abundance of observational and laboratory testing capabilities for this organism, diagnostic interpretation of test results can be challenging and ambiguous. This is partly explained by the chronic nature of M. hyopneumoniae infection and its tropism for lower respiratory tract epithelium, which affects diagnostic sensitivities associated with sampling location and stage of infection. A thorough knowledge of the available tools for routine M. hyopneumoniae diagnostic testing, together with a detailed understanding of infection dynamics, are essential for optimizing sampling strategies and providing confidence in the diagnostic process. This study reviewed known information on sampling and diagnostic tools for M. hyopneumoniae and summarized literature reports of the dynamics of key infection outcomes, including clinical signs, lung lesions, pathogen detection, and humoral immune responses. Such knowledge could facilitate better understanding of the performance of different diagnostic approaches at various stages of infection.