Rgf1p (Rho1p GEF) is required for double-strand break repair in fission yeast [Dataset]
[EN]The dataset includes seven Supplementary Figure Legends about the exchange factor Rgf1p is involved in the repair of DNA double-strand breaks induced by Phl treatment. In S. pombe, the DNA damage checkpoint is activated by Rad3p (ATR homolog), which in turn activates its downstream protein kinas...
| Autores: | , , , |
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| Tipo de recurso: | conjunto de datos |
| Estado: | Versión publicada |
| Fecha de publicación: | 2017 |
| País: | España |
| Institución: | Universidad de Salamanca (USAL) |
| Repositorio: | GREDOS. Repositorio Institucional de la Universidad de Salamanca |
| OAI Identifier: | oai:gredos.usal.es:10366/146284 |
| Acceso en línea: | http://hdl.handle.net/10366/146284 |
| Access Level: | acceso abierto |
| Palabra clave: | Fission Yeast DNA damage Rho1p GEF 2414.10 Micología (Levaduras) 2415.01 Biología Molecular de Microorganismos |
| Sumario: | [EN]The dataset includes seven Supplementary Figure Legends about the exchange factor Rgf1p is involved in the repair of DNA double-strand breaks induced by Phl treatment. In S. pombe, the DNA damage checkpoint is activated by Rad3p (ATR homolog), which in turn activates its downstream protein kinase, Chk1p (67). The rgf1Δ cells are sensitive to CPT and highly sensitive to Phl, both drugs trigger a strong checkpoint response. |
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